%A Jian-cheng He, Can-xing Yuan, Hong-chang Wei, Ru-xing Chen %T Effect of Chinese and western medicine integration on spinning behavior of rats with Parkinson disease %0 Journal Article %D 2003 %J Journal of Integrative Medicine %R 10.3736/jcim20030419 %P 293-295 %V 1 %N 4 %U {http://www.jcimjournal.com/CN/abstract/article_272.shtml} %8 2003-12-20 %X

Objective

To observe the effect of Chinese and western medicine integration on the spinning behavior of rats with Parkinson disease.


Methods

Model of the lateral Parkinson disease was made with injection of 6-hydroxydopamine (6-OHDA) into the black substance of the right side of the brain, and the model rats were treated with madopar and Chinese herbs for nourishing the liver and kidney, clearing collaterals and detoxification. The rat's spinning behavior was observed, and was compared with the normal control group, madopar group and sham-operation group at the same time.


Results

Chinese and western medicine integration could obviously reduce the spinning circles of the rats.


Conclusion

Chinese and western medicine integration can significantly improve the spinning behavior of the model rats.