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Original Clinical Research
Journal of Chinese Integrative Medicine: Volume 9, 2011   Issue 7
Clinical characteristics of patients with reflux esophagitis exhibiting gallbladder heat attacking the stomach or stagnant heat of the liver and stomach syndrome
1. Ji Sun (Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China E-mail: thebest911@hotmail.com)
2. Sheng-liang Zhu (Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China )
3. Shu-ying Ma (Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China )
4. Xiao-su Wang (Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China )
5. Jing Kong (Department of Gastroenterology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China )

Objective: To compare the characteristics of the traditional Chinese medicine (TCM) syndromes of gallbladder heat attacking the stomach and stagnant heat of the liver and stomach in patients with reflux esophagitis (RE), in terms of clinical symptoms, combination of gallbladder conditions, esophageal mucosal inflammation, gastric bile reflux under endoscopy and helicobacter pylori (HP) infection.
Methods: Patients with RE were enrolled from Yueyang Hospital of Integrated Traditional Chinese and Western Medicine from June 2007 to December 2009 and patients exhibiting the syndrome of gallbladder heat attacking the stomach or stagnant heat of the liver and stomach were collected. The patients were requested to complete clinical questionnaires. The general data, characteristics of clinical symptoms, combination of gallbladder conditions, esophageal mucosal inflammation, gastric bile reflux under endoscopy and HP infection of the two patterns were compared.
Results: The average age of the selected patients with gallbladder heat attacking the stomach was older than that of the patients with stagnant heat of the liver and stomach (P<0.01) and the accompanying clinical signs and symptoms were more severe (P<0.01). The incidence of gallbladder diseases in patients with gallbladder heat attacking the stomach was higher than that of the patients with stagnant heat of the liver and stomach (P<0.01). The extent of the esophageal mucosal inflammation under endoscopy as well as the gastric bile reflux and the incidence of HP infection was also more severe (P<0.01).
Conclusion: There are significant differences in several regards between the syndromes of gallbladder heat attacking the stomach and stagnant heat of the liver and stomach in patients with RE. These characteristics may provide sound evidence for differentiation of signs and symptoms for this disease.

Received January 26, 2011; accepted April 23, 2011; published online July 15, 2011.
Full-text LinkOut at PubMed. Journal title in PubMed: Zhong Xi Yi Jie He Xue Bao.
    
Correspondence: Ji Sun; Tel: 025-85811625; E-mail: thebest911@hotmail.com

 

Full text of this article is in Chinese

  
References
1. Chen HZ. Practical internal medicine[M]. 11th ed. Beijing: People’s Medical Publishing House, 2001. 1726. Chinese.
2. Zhu SL, Li Y, Zhu XY, Ma SY. Study into syndrome of gastroesophageal reflux disorders[J]. Shanghai Zhong Yi Yao Za Zhi, 2002, 36(12) : 12-13. Chinese with abstract in English.
  
3. Lundell LR, Dent J, Bennett JR, Blum AL, Armstrong D, Galmiche JP, Johnson F, Hongo M, Richter JE, Spechler SJ, Tytgat GN, Wallin L. Endoscopic assessment of oesophagitis: clinical and functional correlates and further validation of the Los Angeles classification[J]. Gut, 1999, 45(2) : 172-180.
  
4. Chen YB, Pan XQ, Jin LS, Zhang RH, Mao SS, Zhang Q, Yang QJ, Shao QH, Duan XZ, Wen JH, Shen SW. Classification and codes of diseases and Zheng of traditional Chinese medicine[M]. Beijing: Standards Press of China, 1995. 1-3. Chinese.
5. Chen XJ. Internal medicine of traditional Chinese medicine[M]. Shanghai: Shanghai Scientific and Technical Publishers, 2004. 165-168. Chinese.
6. Committee of Chinese Consensus on Gastroesophageal Reflux Disease. Chinese consensus on gastroesophageal reflux disease (2006·10 Sanya)[J]. Zhonghua Nei Ke Za Zhi, 2007, 46(2) : 170-173. Chinese.
  
7. Zheng XY. Guidelines for clinical research on Chinese new herbal medicines (trial implementation)[M]. Beijing: China Medical Science and Technology Press, 2002. 124-129. Chinese.
8. Zhu SL, Ma SY, Cheng YM, Sun J, Sun YS, Li L, Wang XS, Fang SQ. Clinical research of relationships between traditional Chinese medicine syndrome types of gastroesophageal reflux disease and type of reflux[J]. Jiangsu Zhong Yi Yao, 2008, 40(11) : 41-42. Chinese.
  
9. Wang W, Xu GM, Li ZS, Zou DW, Zhu AY, Yu FH. Effects of gastroesophageal reflux and duodenoesophageal reflux on esophageal mucosa[J]. Zhonghua Xiao Hua Za Zhi, 2000, 20(4) : 240-242. Chinese with abstract in English.
  
10. Huang YD, Tu XA. Relationships between bile reflux gastritis and esophagitis and Helicobacter pylori[J]. Shi Yong Lin Chuang Yi Xue, 2004, 5(5) : 12-14. Chinese with abstract in English.
  
11. Sun YS, Zhu SL, Ma SY, Deng YH. Characteristics of the traditional Chinese medicine syndromes of gastroesophageal reflux disease: a report of 260 cases[J]. Jiangsu Zhong Yi Yao, 2004, 25(12) : 41-42. Chinese.
  
12. Zhu SL, Sun YS, Ma SY, Wang XS. Multianalysis of Chinese medical syndromes of gastroesophageal regurgitation[J]. Shanghai Zhong Yi Yao Za Zhi, 2006, 40(10) : 28-29. Chinese with abstract in English.
  
13. Zhu XY, Zhu SL. Relationships between traditional Chinese medicine syndrome types of reflux esophagitis and expression under endoscopy, bile reflux gastritis and Helicobacter pylori[J]. Beijing Zhong Yi, 2004, 23(6) : 323-325. Chinese.
  
  
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