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Original Clinical Research
Journal of Chinese Integrative Medicine: Volume 10, 2012   Issue 4
Weighting coefficients of symptoms and signs in the diagnosis of corresponding TCM syndrome elements of ulcerative colitis based on expert questionnaire investigation
1. Jia-jia Wang (Department of Diagnostics of Traditional Chinese Medicine, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China )
2. Tian-fang Wang (Department of Diagnostics of Traditional Chinese Medicine, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China E-mail: E-mail: tianfangwang2000@yahoo.com.cn)
3. Xiu-yan Wu (Department of Diagnostics of Traditional Chinese Medicine, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China )
4. Yan Zhao (Department of Diagnostics of Traditional Chinese Medicine, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China )
5. Xiao-lin Xue (Department of Diagnostics of Traditional Chinese Medicine, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China )
6. Qing-guo Wang (Department of Clinical Basic Medicine of Traditional Chinese Medicine, School of Preclinical Medicine, Beijing University of Chinese Medicine, Beijing 100029, China )
OBJECTIVE: To define the weighting coefficients of the symptoms and signs in the diagnosis of corresponding traditional Chinese medicine (TCM) syndrome elements of ulcerative colitis based on expert questionnaire investigation.
METHODS: The questionnaire included eight syndrome elements of location and 11 syndrome elements relating to disease characteristics. Experts who answered the questionnaire were titled as associate chief physician or above, and had been practicing as professionals in general practice of medicine of digestive system for a long time. They came from 15 third-grade class-A hospitals (6 provinces and Beijing) in China. The weighting coefficients of the symptoms and signs in the diagnosis of corresponding TCM syndrome elements of ulcerative colitis were identified preliminarily based on consent degree of the experts (mean value and variation coefficient).
RESULTS: There were 9, 6, 14, 5, 9, 8, 12 and 2 symptoms and signs corresponding to 8 TCM syndrome elements related to disease location and the ranges of weighting coefficients were listed as follows: liver, from 7.49 to 4.18; heart, from 6.90 to 5.51; spleen, from 7.96 to 5.55; lung, from 6.30 to 5.27; kidney, from 7.82 to 5.71; stomach, from 7.53 to 6.15; large intestine, from 8.40 to 6.70; bowel collaterals, from 8.49 to 6.41. Numbers of symptoms and signs corresponding to 11 TCM syndrome elements related to disease nature were 13, 8, 17, 18, 17, 18, 6, 11, 2, 10 and 11 and the ranges of weighting coefficients were listed as follows: qi deficiency, from 7.44 to 5.60; blood deficiency, from 7.90 to 5.59; yin deficiency, from 6.88 to 4.91; yang deficiency, from 7.54 to 5.57; dampness, from 7.91 to 4.96; excess heat (fire), from 7.13 to 5.69; excess cold, from 7.51 to 6.14; qi stagnation, from 7.38 to 5.88; qi sinking, from 7.65 to 7.43; blood stasis, from 7.60 to 5.79; fluid retention, from 7.08 to 4.46.
CONCLUSION: On the basis of previous document research and clinical research in ulcerative colitis, the expert questionnaire can collect consensus opinions of experts. The weighting coefficients of the symptoms and signs in the diagnosis of corresponding TCM syndrome elements of ulcerative colitis are defined preliminarily. Thereby it will lay the foundation for establishing differentiation criteria of ulcerative colitis based on TCM syndrome elements.

Received August 23, 2011; accepted December 8, 2011; published online April 15, 2012.
Full-text LinkOut at PubMed. Journal title in PubMed: Zhong Xi Yi Jie He Xue Bao.

基金项目:国家重点基础研究发展计划(973计划)资助项目(No. 2003CB517101); 北京中医药大学基本科研业务费资助项目(No. 2011-CXTD-08); 北京中医药大学科研基金资助项目
Correspondence: Tian-fang Wang, MD, Professor; Tel: 010-64286661; E-mail: tianfangwang2000@yahoo.com.cn

Full text of this article is in Chinese

  
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