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Journal of Chinese Integrative Medicine: Volume 10, 2012   Issue 2,  Pages: 117-127

DOI: 10.3736/jcim20120201
Review Article
A recent update in research on the antihepatotoxic potential of medicinal plants
1. Anju Dhiman (Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, Haryana, India E-mail: ad_mdu@rediffmail.com)
2. Arun Nanda (Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, Haryana, India )
3. Sayeed Ahmad (Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India )
ABSTRACT: Hepatic damage is a global metabolic and epidemic disease, affecting essential biochemical activities in almost every age group. Conventional drugs used in the treatment of liver disorders are often inadequate. Also, the spectrum of liver abnormalities caused by allopathic drugs is found to be broad. In view of severely undesirable side effects of synthetic agents, it is necessary to search for alternative drugs for the treatment of liver diseases to replace the currently used drugs, which are of doubtful efficacy and safety. Therefore, there is growing focus to follow systematic research methodology and to evaluate scientific basis for the traditional herbal medicines that are claimed to possess hepatoprotective activities. Use of herbal drugs in the treatment of liver diseases has a long tradition, especially in Eastern medicine and can be traced back as far as 2100 B.C. in ancient China (Xia Dynasty) and India (Vedic period), but evidence for efficacy is sparse. The current study is aimed at providing an overview of clinical and experimental studies carried out on the most effective and commonly used hepatoprotective plants and their beneficial aspects.
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Dhiman A, Nanda A, Ahmad S. A recent update in research on the antihepatotoxic potential of medicinal plants. J Chin Integr Med / Zhong Xi Yi Jie He Xue Bao. 2012; 10(2): 117-127.
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