Updated Monday, September 25, 2017
 Journal Tools
RSS Feed
Sample Copy
Submit a Manuscript
Contact Us
Subscription
Advertising
Thanking Peer Reviewers
 Language Polishing
Journal of Chinese Integrative Medicine: Volume 10, 2012   Issue 4,  Pages: 357-361

DOI: 10.3736/jcim20120401
Global Views
The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies?
1. Thomas Efferth (Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, Johannes Gutenberg University, Staudinger Weg 5, 55128 Mainz, Germany E-mail: E-mail: efferth@uni-mainz.de)
2. Henry Johannes Greten (Heidelberg School of Chinese Medicine, Karlsruher Straβe 12, 69126 Heidelberg, Germany )
Welcome to JIM! You are the number 10406 reader of this article!
Download Article:
[Full Text]      [PDF]      [Next]      [This Issue]
Please cite this article as:
Efferth T, Greten HJ. The European directive on traditional herbal medicinal products: friend or foe for plant-based therapies?. J Chin Integr Med / Zhong Xi Yi Jie He Xue Bao. 2012; 10(4): 357-361.
References:
1The European Parliament and the Council of the European Union. Directive 2004/24/EC of the European Parliament and of the Council of 31 March 2004 amending, as regards traditional herbal medicinal products, Directive 2001/83/EC on the Community code relating to medicinal products for human use. (2004-04-30) [2012-02-17]. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:32004L0024:EN:NOT.
2The European Parliament and the Council of the European Union. Directive 2001/83/EC of the European Parliament and of the Council of 6 November 2001 on the Community code relating to medicinal products for human use. (2001-11-28) [2012-02-17]. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:32001L0083:EN:NOT.
3Medicines and Healthcare products Regulatory Agency, UK. Guidance for Retailers, Wholesalers, Importers and Manufacturers on the Requirements of the THMRS. (2007-03) [2012-02-17]. http://www.mhra.gov.uk/home/groups/pl-p/documents/websiteresources/con2030651.pdf.
4Medicines and Healthcare products Regulatory Agency, UK. Guidance on Use of HMPC Monographs to Demonstrate Safety and Traditional Use. (2007-12) [2012-02-17]. http://www.mhra.gov.uk/home/groups/es-herbal/documents/websiteresources/con2033554.pdf.
5Medicines and Healthcare products Regulatory Agency, UK. Organic Herbal Ingredients and Labelling under the Traditional Herbal Medicines Registration (THR) Scheme: Guidance for Applicants/Registration Holders. [2012-02-17]. http://www.mhra.gov.uk/home/groups/es-herbal/documents/websiteresources/con114427.pdf.
6Medicines and Healthcare products Regulatory Agency, UK. Guidance on Transitional Arrangements for the Directive on Traditional Herbal Medicinal Products (Directive 2004/24/EC, amending Directive 2001/83/EC). (2010-08) [2012-02-17]. http://www.mhra.gov.uk/home/groups/es-herbal/documents/websiteresources/con090969.pdf.
7Medicines and Healthcare products Regulatory Agency, UK. Registered Traditional Herbal Medicines: Guidance on Consumer Advertising. (2009-10) [2012-02-17]. http://www.mhra.gov.uk/home/groups/comms-ic/documents/websiteresources/con063043.pdf.
8Medicines and Healthcare products Regulatory Agency, UK. Guidance on Arrangements for the Transfer of Certain Herbal Products with a Marketing Authorisation to Traditional Herbal Registration Status. (2009-01) [2012-02-17]. http://www.mhra.gov.uk/home/groups/es-herbal/documents/websiteresources/con038614.pdf.
9Medicines and Healthcare products Regulatory Agency, UK. Public Perceptions of Herbal Medicines: General Public Qualitative and Quantitative Research. (2008-11) [2012-02-17]. http://www.mhra.gov.uk/home/groups/comms-po/documents/news/con036073.pdf.
10Encyclopedia Britannica. Food. [2012-02-17]. http://www.britannica.com/EBchecked/topic/212568/food.
11Wikipedia. Dietary supplements. [2012-02-17]. http://en.wikipedia.org/wiki/Dietary_supplement.
12European Commission. Health and Nutritional Claims. (2009-11-20) [2012-02-17]. http://ec.europa.eu/food/food/labellingnutrition/claims/index_en.htm.
13Encyclopedia Britannica. Medicine. [2012-02-17]. http://www.britannica.com/EBchecked/topic/372431/medicine.
14The European Parliament and the Council of the European Union. Regulation (EC) No. 178/2002 of the European Parliament and of the Council of 28 January 2002 laying down the general principles and requirements of food law, establishing the European Food Safety Authority laying down procedures in matters of food safety. (2002-02-01) [2012-02-17]. http://www.food.gov.uk/multimedia/pdfs/1782002ecregulation.pdf.
15The European Parliament and the Council of the European Union. Regulation (EC) No 258/97 of the European Parliament and of the Council of 27 January 1997 concerning novel foods and novel food ingredients. (1997-02-14) [2012-02-17]. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:31997R0258:EN:NOT.
16The European Parliament and the Council of the European Union. Directive 2002/46/EC of the European Parliament and of the Council of 10 June 2002 on the approximation of the laws of the Member States relating to food supplements. (2002-07-12) [2012-02-17]. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=CELEX:32002L0046:EN:NOT.
17EFSA Scientific Committee. Guidance on Safety assessment of botanicals and botanical preparations intended for use as ingredients in food supplements[J].EFSA J, 2009, 7(9): 1249-1273.  
18Efferth T, Kaina B. Toxicities by herbal medicines with emphasis to traditional Chinese medicine[J].Curr Drug Metab, 2011, 12(10): 989-996.  
19Youns M, Hoheisel JD, Efferth T. Toxicogenomics for the prediction of toxicity related to herbs from traditional Chinese medicine[J].Planta Med, 2010, 76(17): 2019-2025.  
20Eichhorn T, Greten HJ, Efferth T. Self-medication with nutritional supplements and herbal over-the-counter products[J].Nat Products Bioprospect, 2011, 1(2): 62-70.  
21Kober M, Pohl K, Efferth T. Molecular mechanisms underlying St. John’s wort drug interactions[J].Curr Drug Metab, 2008, 9(10): 1027-1037.  
22Efferth T, Koch E. Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy[J].Curr Drug Targets, 2011, 12(1): 122-132.  
23Jia H. Traditional Chinese medicines hampered by EU regulations. (2011-06-10) [2012-02-17]. http://www.rsc.org/chemistryworld/News/2011/June/10061102.asp.
24Lewith G, Barlow F, Eyles C, Flower A, Hall S, Hopwood V, Walker J. The context and meaning of placebos for complementary medicine[J].Forsch Komplementmed, 2009, 16(6): 404-412.  
25Staud R. Effectiveness of CAM therapy: understanding the evidence[J].Rheum Dis Clin North Am, 2011, 37(1): 9-17.  
26Lincoln T. Toxicology: danger in the diet[J].Nature, 2007, 448(7150): 148.  
27Konkimalla VB, Efferth T. Evidence-based Chinese medicine for cancer therapy[J].J Ethnopharmacol, 2008, 116(2): 207-210.  
28Efferth T, Li PC, Konkimalla VS, Kaina B. From traditional Chinese medicine to rational cancer therapy[J].Trends Mol Med, 2007, 13(8): 353-361.  
29Efferth T, Fu YJ, Zu YG, Schwarz G, Konkimalla VS, Wink M. Molecular target-guided tumor therapy with natural products derived from traditional Chinese medicine[J].Curr Med Chem, 2007, 14(19): 2024-2032.  
30Abdel-Rahman A, Anyangwe N, Carlacci L, Casper S, Danam RP, Enongene E, Erives G, Fabricant D, Gudi R, Hilmas CJ, Hines F, Howard P, Levy D, Lin Y, Moore RJ, Pfeiler E, Thurmond TS, Turujman S, Walker NJ. The safety and regulation of natural products used as foods and food ingredients[J].Toxicol Sci, 2011, 123(2): 333-348.  
31Gao H, Wang Z, Li Y, Qian Z. Overview of the quality standard research of traditional Chinese medicine[J].Front Med, 2011, 5(2): 195-202.  
32Ruparel P, Lockwood B. The quality of commercially available herbal products[J].Nat Prod Commun, 2011, 6(5): 733-744.  
33Li SP, Zhao J, Yang B. Strategies for quality control of Chinese medicines[J].J Pharm Biomed Anal, 2011, 55(4): 802-809.  
34Cosyns JP. Aristolochic acid and “Chinese herbs nephropathy”: a review of the evidence to date[J].Drug Saf, 2003, 26(1): 33-48.  
35Nortier JL, Vanherweghem JL. Renal interstitial fibrosis and urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). Toxicology. 2002; 181-182: 577-580.
36Debelle FD, Vanherweghem JL, Nortier JL. Aristolochic acid nephropathy: a worldwide problem[J].Kidney Int, 2008, 74(2): 158-169.  
 Home | Current Issue | Past Issues | SearchRSS
Copyright © 2013-2018 by JIM Editorial Office. All rights reserved. ISSN 2095-4964; CN 31-2083/R. 沪ICP备110264号