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Journal of Chinese Integrative Medicine: Volume 9, 2011   Issue 7,  Pages: 752-760

DOI: 10.3736/jcim20110709
Original Experimental Research
Potentized homeopathic drug Arsenicum Album 30C positively modulates protein biomarkers and gene expressions in Saccharomyces cerevisae exposed to arsenate
1. Durba Das (Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India )
2. Arnab De (Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India )
3. Suman Dutta (Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India )
4. Raktim Biswas (Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India )
5. Naoual Boujedaini (Boiron Laboratory, Lyon, France )
6. Anisur Rahman Khuda-Bukhsh (Cytogenetics and Molecular Biology Laboratory, Department of Zoology, University of Kalyani, Kalyani 741235, India E-mail: prof_arkb@yahoo.co.in, khudabukhsh_48@rediffmail.com)
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Please cite this article as:
Das D, De A, Dutta S, Biswas R, Boujedaini N, Khuda-Bukhsh AR. Potentized homeopathic drug Arsenicum Album 30C positively modulates protein biomarkers and gene expressions in Saccharomyces cerevisae exposed to arsenate. J Chin Integr Med / Zhong Xi Yi Jie He Xue Bao. 2011; 9(7): 752-760.
References:
1Khuda-Bukhsh AR, Pathak S. Homeopathic drug discovery: theory update and methodological aspect[J].Expert Opin Drug Discov, 2008, 3(8): 979-990.  
2Khuda-Bukhsh AR. Laboratory research in homeopathy: pro[J].Integr Cancer Ther, 2006, 5(4): 320-332.  
3Belon P, Banerjee A, Karmakar SR, Biswas SJ, Choudhury SC, Banerjee P, Das JK, Pathak S, Guha B, Paul S, Bhattacharjee N, Khuda-Bukhsh AR. Homeopathic remedy for arsenic toxicity?: Evidence-based findings from a randomized placebo-controlled double blind human trial[J].Sci Total Environ, 2007, 384(1-3): 141-150.  
4Barchowsky A, Roussel RR, Klei LR, James PE, Ganju N, Smith KR, Dudek EJ. Low levels of arsenic trioxide stimulate proliferative signals in primary vascular cells without activating stress effector pathways[J].Toxicol Appl Pharmacol, 1999, 159(1): 65-75.  
5Chen YC, Lin-Shiau SY, Lin JK. Involvement of reactive oxygen species and caspase 3 activation in arsenite-induced apoptosis[J].J Cell Physiol, 1998, 177(2): 324-333.  
6Wang TS, Kuo CF, Jan KY, Huang H. Arsenite induces apoptosis in Chinese hamster ovary cells by generation of reactive oxygen species[J].J Cell Physiol, 1996, 169(2): 256-268.  
7Banerjee P, Biswas SJ, Belon P, Khuda-Bukhsh AR. A potentized homeopathic drug, Arsenicum Album 200, can ameliorate genotoxicity induced by repeated injections of arsenic trioxide in mice[J].J Vet Med A Physiol Pathol Clin Med, 2007, 54(7): 370-376.  
8Datta S, Mallick P, Bukhsh AR. Efficacy of a potentized homoeopathic drug (Arsenicum Album-30) in reducing genotoxic effects produced by arsenic trioxide in mice: comparative studies of pre-, post- and combined pre- and post-oral administration and comparative efficacy of two microdoses[J].Complement Ther Med, 1999, 7(2): 62-75.  
9Banerjee P, Bhattacharyya SS, Bhattacharjee N, Pathak S, Boujedaini N, Belon P, Khuda-Bukhsh AR. Ascorbic acid combats arsenic-induced oxidative stress in mice liver[J].Ecotoxicol Environ Saf, 2009, 72(2): 639-649.  
10Mouriquand G, Cier A, Boiron J, Edel V, Chighizola R. Mobilization of fixed arsenic by the effect of infinitesimal doses & changes of the vestibular chronological index[J].C R Hebd Seances Acad Sci, 1959, 249(1): 18-20. French with abstract in English
11Chikramane PS, Suresh AK, Bellare JR, Kane SG. Extreme homeopathic dilutions retain starting materials: a nanoparticulate perspective[J].Homeopathy, 2010, 99(4): 231-242.  
12Boiron J, Abecassis J, Belon P. A pharmacological study of the retention and mobilization of arsenic, as caused by Hahnemanian potencies of Arsenicum Album. In: Boiron J, Abecassis J, Belon P. Aspects of research in homeopathy[M]. Vol 1. Lyon: Boiron, 1983.  
13Betti L, Brizzi M, Nani D, Peruzzi M. A pilot statistical study with homoeopathic potencies of arsenicum album in wheat germination as a simple model[J].Br Homeopath J, 1994, 83(4): 195-201.  
14Lahnstein L, Binder M, Thurneysen A, Frei-Erb M, Betti L, Peruzzi M, Heusser P, Baumgartner S. Isopathic treatment effects of Arsenicum album 45× on wheat seedling growth — further reproduction trials[J].Homeopathy, 2009, 98(4): 198-207.  
15Jger T, Scherr C, Wolf U, Simon M, Heusser P, Baumgartner S. Investigation of arsenic-stressed yeast (Saccharomyces cerevisiae) as a bioassay in homeopathic basic research[J].ScientificWorldJournal, 2011, 11: 568-583.  
16Tepari R, Stuparevi I, Mrsa V. Increased mortality of Saccharomyces cerevisiae cell wall protein mutants[J].Microbiology, 2004, 150(Pt 10): 3145-3150.  
17Aust SD. Thiobarbituric acid assay reactants. In: Tyson CA, Frazier ZM. Methods in toxicology. Vol 1B: In vitro toxity indicators[M]. New York: Academic Press, 1994. 367-376.  
18Lushchak V, Semchyshyn H, Mandryk S, Lushchak O. Possible role of superoxide dismutases in the yeast Saccharomyces cerevisiae under respiratory conditions[J].Arch Biochem Biophys, 2005, 441(1): 35-40.  
19Ellman GL. Tissue sulfhydryl groups.[J].Arch Biochem Biophys, 1959, 82(1): 70-77.  
20Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding[J].Anal Biochem, 1976, 72: 248-254.  
21Maehly AC, Chance B. Assay of catalases and peroxidases. In: Colowick SP, Kaplan NO. Methods in enzymology. Vol 2: Preparation and assay of enzymes[M]. New York: Academic Press, 1955. 764-774.  
22Nishikimi M, Appaji N, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen[J].Biochem Biophys Res Commun, 1972, 46(2): 849-854.  
23Miloshev G, Mihaylov I, Anachkova B. Application of the single cell gel electrophoresis on yeast cells[J].Mutat Res, 2002, 513(1-2): 69-74.  
24Linde K, Jonas WB, Melchart D, Worku F, Wagner H, Eitel F. Critical review and meta-analysis of serial agitated dilutions in experimental toxicology[J].Hum Exp Toxicol, 1994, 13(7): 481-492.  
25Scherr C, Baumgartner S, Spranger J, Simon M. Effects of potentised substances on growth kinetics of Saccharomyces cerevisiae and Schizosaccharomyces pombe[J].Forsch Komplementmed, 2006, 13(5): 298-306.  
26Nystrm T. Role of oxidative carbonylation in protein quality control and senescence[J].EMBO J, 2005, 24(7): 1311-1317.  
27Imlay JA, Linn S. DNA damage and oxygen radical toxicity[J].Science, 1988, 240(4857): 1302-1309.  
28Panda SK. Advances in stress physiology of plants[M]. Jodhpur: Scientific Publishers, 2002. 1-13.  
29Kuge S, Jones N, Nomoto A. Regulation of yAP-1 nuclear localization in response to oxidative stress[J].EMBO J, 1997, 16(7): 1710-1720.  
30Lee RE, Puente LG, Kaern M, Megeney LA. A non-death role of the yeast metacaspase: Yca1p alters cell cycle dynamics[J].PLoS One, 2008, 3(8): e2956.  
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