[an error occurred while processing this directive]

Journal of Chinese Integrative Medicine ›› 2004, Vol. 2 ›› Issue (3): 172-174.doi: 10.3736/jcim20040305

• Youth Forum • Previous Articles     Next Articles

Relationship between glucocorticoid receptor and deficiency-syndrome and the regulation of traditional Chinese medicine

Yong Li   

  1. Department of Traditional Chinese Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, China
  • Online:2004-06-20 Published:2018-10-25

The glucocorticoid receptor (GR) is a ligand-dependent transcription factor belonging to the nuclear hormone receptor superfamily. Due to its almost ubiquitous expression, GR plays an important role in many physiological and pathological processes. These include regulation of homeostasis, adaptation to stress, and modulation of central nervous system. In addition, GR is a major modulator of the immune system due to its proficient anti-inflammatory and immunosuppressive activity; and its function is important for proper regulation of many physiological processes. The exploration on the regulation of traditional Chinese medicine on GR has established a modern physiological and pathological foundation for research of traditional Chinese medicine.

Key words: glucocorticoid receptors, traditional Chinese medicine, deficiency syndrome, targetings

CLC Number: 

  • R392.11
[1] 徐克川, 张善徵 . 甲亢类阴虚大鼠肝胞液糖皮质激素受体的实验研究[J]. 广州中医学院学报, 1990,7(3):145-149
[2] 凌昌全, 李敏, 朱德增 , 等. 阴阳虚证与糖皮质激素受体关系的临床与实验研究[J]. 浙江中西医结合杂志, 2001,11(9):532-533
[3] 凌昌全, 陈喆, 俞超芹 , 等. 52例阴虚阳虚患者外周血混合白细胞糖皮质激素受体的实验观察[J]. 中医杂志, 1998,39(10):619-620
[4] 刘福春, 翟美芙 . 老年及老年虚证病人周围血白细胞糖皮质激素受体的研究[J]. 中医杂志, 1989,30(7):40-42
[5] 张广宇, 谢竹藩 . 虚寒及虚热证患者血浆皮质醇及其受体观察[J]. 中西医结合杂志, 1991,11(11):664-665
[6] 凌昌全, 李敏, 谭金兴 , 等. 中药对糖皮质激素受体保护作用的实验研究[J]. 中国中西医结合杂志, 1999,19(5):302-303
doi: 10.7661/CJIM.1999.5.302
[7] 张家庆, 刘志民 . 阳虚患者单个核及多形核白细胞糖皮质激素受体改变[J]. 中西医结合杂志, 1990,10(4):215-216
doi: 10.7661/CJIM.1990.4.215
[8] 姚连初 . 肾气丸对原发肾病综合征患者外周血糖皮质激素受体水平的影响[J]. 中成药, 2000,22(10):704-705
doi: 10.3969/j.issn.1001-1528.2000.10.014
[9] 马以泉 . 六味地黄丸对肾病综合征患儿外周血糖皮质激素受体水平的影响[J]. 浙江中医学院学报, 2000,24(3):49
[10] 李曙光, 杨柳松, 王浩丹 , 等. 小柴胡汤治疗肾病综合征机理的探讨[J]. 山东医科大学学报, 1998,36(4):286-288
[11] 张玲娟, 沈自尹, 王文健 , 等. 补肾益气法对淋巴细胞糖皮质激素受体老年性改变的影响[J]. 中西医结合杂志, 1990,10(10):583-585
[12] 凌昌全, 李敏, 苏永华 , 等. 人参茎叶皂苷对失血性休克大鼠糖皮质激素受体的影响[J]. 中草药, 2003,34(5):433-436
[13] 李敏, 凌昌全, 沈志雷 , 等. 人参茎叶皂苷对热损伤大鼠糖皮质激素受体的影响[J]. 第二军医大学学报, 2003,24(8):S16-F3
[14] 奚蓓莉, 吴敦序 , 包照日格图, 等.补肾定喘汤对哮喘大鼠肺组织糖皮质激素受体的影响[J]. 标记免疫分析与临床, 1997,4(4):217-220
[15] 赵伟康, 金国琴, 王润平 , 等. 固真方对老年大鼠下丘脑-垂体-甲状腺-胸腺轴作用的研究[J]. 中医杂志, 1997,38(6):363-365
[16] 王光利 . 小青龙汤治疗哮喘药理机制探讨[J]. 临床急诊杂志, 2001,2(2):56-58
[17] 包照日格图, 吴敦序, 陈淑俊 , 等. 龟芪散对哮喘大鼠糖皮质激素受体及皮质酮的影响[J]. 中成药, 1998,20(2):25-28
[18] 杨霞, 王浩丹, 侯桂华 , 等. 小柴胡汤对糖皮质激素受体及其mRNA的调节作用[J]. 中国病理生理杂志, 2000,16(12):1304-1306
[19] 刘毅, 叶松柏, 金彰红 . 雷公藤多苷对糖皮质激素受体的影响[J]. 川北医学院学报, 2000,15(2):4-6
[20] Chung E, Lee KY, Lee YJ , et al. Ginsenoside Rg1 down-regulates glucocorticoid receptor and displays synergistic effects with cAMP[J]. Steroids, 1998,63(7-8):421-424
[21] 步世忠, 许金廉, 孙继虎 , 等. 柴胡皂苷d上调HL-60细胞糖皮质激素受体mRNA并诱导细胞凋亡[J]. 中华血液学杂志, 1999,20(7):354-356
[22] 赵晓山, 罗仁 . 肾虚证相关基因的研究[J]. 中西医结合学报, 2003,1(1):18-20
Zhao XS, Luo R . Study of genes related with kidney deficiency syndrome[J]. Zhong Xi Yi Jie He Xue Bao, 2003,1(1):18-20
[1] Wei-Jun Zhang, Da-Ming Su , Ka-Kit Hui. The development and current status of integrative medicine at UCLA. Journal of Chinese Integrative Medicine, 2012, 10(9): 953-960.
[2] Liang-ping Hu, Xiao-lei Bao, Chen-long Lv. Two-factor designs unable to examine the interactions (Part 2). Journal of Chinese Integrative Medicine, 2012, 10(9): 966-969.
[3] Ming T. Tan , Jian-ping Liu , Lixing Lao. Adequate application of quantitative and qualitative statistic analytic methods in acupuncture clinical trials. Journal of Chinese Integrative Medicine, 2012, 10(8): 847-852.
[4] Fan Yin, Ziyi Fan. Dr. Wu: A beautiful, moving and meditative song — In memory of Dr. Jing Nuan Wu, a pioneer of acupuncture and a Chinese medicine doctor in the United States. Journal of Chinese Integrative Medicine, 2012, 10(8): 837-840.
[5] Liang-ping Hu, Xiao-lei Bao, Chen-yi Guo . Two-factor designs unable to examine the interactions (Part 1). Journal of Chinese Integrative Medicine, 2012, 10(8): 853-857.
[6] Claudia Maria Sous, Mario Goncalves, Jorge Machado, Thomas Efferth, Tobias Greten , Petra Froeschen , Henry J. Greten. Effects of qigong on performance-related anxiety and physiological stress functions in transverse flute music schoolchildren: A feasibility study. Journal of Chinese Integrative Medicine, 2012, 10(8): 858-865.
[7] Liang-ping Hu , Xiao-lei Bao, Chen-long Lü . How to choose an appropriate experimental design type (Part 2). Journal of Chinese Integrative Medicine, 2012, 10(7): 738-742.
[8] David Sibbritt, Pamela van der Riet, Saowapa Dedkhard, Kannapatch Srithong. Rehabilitation of stroke patients using traditional Thai massage, herbal treatments and physical therapies. Journal of Chinese Integrative Medicine, 2012, 10(7): 743-750.
[9] C. Matos Luís, J. Goncalves Mário, R. Silva António, G. Mendes Joaquim, P. Machado Jorge, J. Greten Henry. Assessment of Qigong-related effects by infrared thermography: A case study. Journal of Chinese Integrative Medicine, 2012, 10(6): 663-666.
[10] Liang-ping Hu, Xiao-lei Bao. How to choose an appropriate experimental design type (Part 1). Journal of Chinese Integrative Medicine, 2012, 10(6): 615-618.
[11] Qing-hui Zhou . Assessment of research papers in medical university staff evaluation. Journal of Chinese Integrative Medicine, 2012, 10(6): 707-711.
[12] Yathiraj Ashwini, Mohamed Rafiq, Gollapalle L. Viswanatha, Subbanna Rajesh, Selvam Senthilraja, Mohammed Azeemuddin, Suryakanth D. Anturlikar, Paramesh Rangesh, Pralhad S. Patki . Polyherbal formulation Bresol® protects the mast cells against compound 48/80-induced disruption and histamine release: A non-immunological mechanism of mast cell stabilization. Journal of Chinese Integrative Medicine, 2012, 10(6): 690-694.
[13] Liang-ping Hu, Xiao-lei Bao, Qi Wang . The balance principle in scientific research. Journal of Chinese Integrative Medicine, 2012, 10(5): 504-507.
[14] Fan Yin . The first acupuncture center in the United States: An interview with Dr. Yao Wu Lee, Washington Acupuncture Center. Journal of Chinese Integrative Medicine, 2012, 10(5): 481-492.
[15] Qin-hui Fu, Jian Pei, Qi Jia, Yi Song, Yue-hua Gu, Xiao-xin You . Acupuncture treatment programs for post-stroke motor rehabilitation in community hospitals: Study protocol of a multicenter, randomized, controlled trial. Journal of Chinese Integrative Medicine, 2012, 10(5): 516-524.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Wei-xiong Liang. Problems-solving strategies in clinical treatment guideline for traditional Chinese medicine and integrative medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 1-4
[2] Zhao-guo Li. Discussion on English translation of commonly used sentences in traditional Chinese medicine: part one. Journal of Chinese Integrative Medicine, 2008, 6(1): 107-110
[3] Jun Hu, Jian-ping Liu. Non-invasive physical treatments for chronic/recurrent headache. Journal of Chinese Integrative Medicine, 2008, 6(1): 31
[4] Xue-mei Liu, Qi-fu Huang, Yun-ling Zhang, Jin-li Lou, Hong-sheng Liu, Hong Zheng. Effects of Tribulus terrestris L. saponion on apoptosis of cortical neurons induced by hypoxia-reoxygenation in rats. Journal of Chinese Integrative Medicine, 2008, 6(1): 45-50
[5] . Uniform requirements for manuscripts submitted to biomedical journals: Writing and editing for biomedical publication (Chinese version, part two). Journal of Chinese Integrative Medicine, 2010, 8(11): 1001-1005
[6] Daniel Weber, Janelle M Wheat, Geoffrey M Currie. Inflammation and cancer: Tumor initiation, progression and metastasis,and Chinese botanical medicines. Journal of Chinese Integrative Medicine, 2010, 8(11): 1006-1013
[7] Hong Liu , Guo-liang Zhang, Li Shen , Zhen Zeng, Bao-luo Zhou, Cheng-hai Liu, Guang Nie . Application and evaluation of a pseudotyped virus assay for screening herbs for anti-H5Nl avian influenza virus. Journal of Chinese Integrative Medicine, 2010, 8(11): 1036-1040
[8] Zhao-guo Li . A discussion of English translation of 1995 and 1997 Chinese National Standards of Traditional Chinese Medical Terminologies for Clinical Diagnosis and Treatment. Journal of Chinese Integrative Medicine, 2010, 8(11): 1090-1096
[9] Rui Jin, Bing Zhang. A complexity analysis of Chinese herbal property theory: the multiple formations of herbal property (Part 1). Journal of Chinese Integrative Medicine, 2012, 10(11): 1198-1205
[10] Hui-min Liu, Xian-bo Wang, Yu-juan Chang, Li-li Gu. Systematic review and meta-analysis of randomized controlled trials of integrative medicine therapy for treatment of chronic severe hepatitis. Journal of Chinese Integrative Medicine, 2012, 10(11): 1211-1228
[an error occurred while processing this directive]