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Journal of Integrative Medicine ›› 2014, Vol. 12 ›› Issue (1): 52-58.doi: 10.1016/S2095-4964(14)60005-4

• Research Article • Previous Articles     Next Articles

In-house preparation and characterization of an Ayurvedic bhasma: Praval bhasma

Amrita Mishraa,b, Arun K. Mishraa, Om Prakash Tiwaria, Shivesh Jhab   

  1. a School of Pharmaceutical Sciences, IFTM University, Moradabad 244001, India
    b Department of Pharmaceutical Sciences, Birla Institute of Technology, Ranchi 835215, India
  • Received:2013-08-25 Accepted:2013-10-15 Online:2014-01-10 Published:2014-01-15

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Objective

To prepare the Praval bhasma (PB) and to perform its characterization. 

Methods

The preparation was performed strictly as per method prescribed in Ayurvedic formulary of India followed by preliminary tests including Nischandratva, Rekhapurnatvam, Varitaramtavm, Nisvadutvam and Amla pariksha. The physicochemical characterization was done with the use of instrumental techniques such as Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X ray diffraction (XRD), and energy dispersive X-ray (EDAX). 

Results

The FTIR bands appearing in final product spectra showed a significant shift in infrared vibration frequency as well as intensity when compared with the raw material, which was indicative of formulation of bhasma. The XRD analysis revealed that raw material contained CaCO3 whereas in case of final product of bhasma, CaO was identified. SEM analysis revealed the difference in particles size of bhasma (10-15 μm) and raw material (100-150 μm). The EDAX analysis showed presence of different concentration of carbon in both the samples. 

Conclusion

It may be concluded that modern analytical techniques may be involved to evaluate the quality aspects of PB. The findings of the present research work may be helpful for further formulation and standardization of PB in routine analysis.

Key words: Praval bhasma, Characterization, Ayurveda, Preparation process

Figure 1

Praval (red coral)"

Figure 2

Flow chart of this processFTIR: Fourier transform infrared."

Figure 3

Image of A: Dola yantra, B: sealed sarava samputa and C: sealed sarava samputa in Gajaputa"

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Figure 4

The X-ray diffraction peaks of raw Praval (B-1) and Praval bhasma (B-2) Y axis represents relative intensity and X axis represents 2θ values."

Figure 5

FTIR spectra of raw Praval (B-1) and Praval bhasma (B-2)"

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Figure 6

Scanning electron micrograph of raw Praval (B1) and Praval bhasma (B2)"

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