[an error occurred while processing this directive]

Journal of Integrative Medicine ›› 2014, Vol. 12 ›› Issue (3): 131-134.doi: 10.1016/S2095-4964(14)60024-8

• Review •     Next Articles

Can moxibustion, an ancient treatment modality, be evaluated in a double-blind randomized controlled trial? — A narrative review

Bai-xiao Zhaoa, Hai-Yong Chenb, Xue-yong Shenc, Lixing Laoa,b,d   

  1. School of Acupuncture, Beijing University of Chinese Medicine, Beijing 100029, China
    School of Chinese Medicine, The University of Hong Kong, Hong Kong, China
    College of Acupuncture-Moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    Center for Integrative Medicine, School of Medicine, University of Maryland, Baltimore, Maryland 21201, USA
  • Received:2014-04-04 Accepted:2014-04-15 Online:2014-05-10 Published:2014-05-15

For thousands of years, moxibustion has been used for various diseases in China and other Asian countries. Despite the recent surge in Chinese herbal studies, few randomized controlled trials have been conducted on this modality, possibly due to the lacking of suitable double blinding methodology. This is a review of extant sham moxa devices and an introduction to a recently developed device that needs further validation.

Key words: Moxibustion, Direct moxibustion, Indirect moxibustion, Randomized controlled trial, Reviews

Figure 1

Real and sham moxa devices by Zhao et al[13]The sham device has a thermal-insulating plate."

"

Figure 2

Zhao’s modified moxa device and proposed sham moxa device(A) The new moxa device developed by Professor Zhao. (B) The proposed sham moxa device with smaller air-pores to lower therapeutic temperature."

[1] Wu JN. Ling shu or the spiritual pivot[M]. Honolulu: University of Hawaii Press, 1993: 234-237
[2] Lao L . Acupuncture techniques and devices[J]. J Altern Complement Med, 1996,2(1):23-25
doi: 10.1089/acm.1996.2.23
[3] Cheng CW, Fu SF, Zhou QH, Wu TX, Shang HC, Tang XD, Liu ZS, Liu J, Lin ZX, Lao L, Lü AP, Zhang BL, Liu BY, Bian ZX . Extending the CONSORT Statement to moxibustion[J]. J Integr Med, 2013,11(1):54-63
doi: 10.3736/jintegrmed2013009
[4] Cheng X. Chinese acupuncture and moxibustion.3rd ed[M]. Beijing: Foreign Languages Press, 2010: 361-370
[5] Cardini F, Weixin H . Moxibustion for correction of breech presentation: a randomized controlled trial[J]. JAMA, 1998,280(18):1580-1584
doi: 10.1001/jama.280.18.1580
[6] Guittier MJ, Pichon M, Dong H, Irion O, Boulvain M . Moxibustion for breech version: a randomized controlled trial[J]. Obstet Gynecol, 2009,114(5):1034-1440
doi: 10.1097/AOG.0b013e3181bc707a
[7] Do CK, Smith CA, Dahlen H, Bisits A, Schmied V . Moxibustion for cephalic version: a feasibility randomised controlled trial[J]. BMC Complement Altern Med, 2011,11:81
doi: 10.1186/1472-6882-11-81
[8] Vas J, Aranda-Regules JM, Modesto M, Ramos-Monserrat M, Barón M, Aguilar I, Benítez-Parejo N, Ramírez-Carmona C, Rivas-Ruiz F . Using moxibustion in primary healthcare to correct non-vertex presentation: a multicentre randomised controlled trial[J]. Acupunct Med, 2013,31(1):31-38
doi: 10.1136/acupmed-2012-010261
[9] Park JE, Lee MS, Jung S, Kim A, Kang K, Choi J, Park J, Choi SM . Moxibustion for treating menopausal hot flashes: a randomized clinical trial[J]. Menopause, 2009,16(4):660-665
doi: 10.1097/gme.0b013e318198cdf7
[10] Park JE, Sul JU, Kang K, Shin BC, Hong KE, Choi SM . The effectiveness of moxibustion for the treatment of functional constipation: a randomized, sham-controlled, patient blinded, pilot clinical trial[J]. BMC Complement Altern Med, 2011,11:124
doi: 10.1186/1472-6882-11-124
[11] Kim HG, Yoo SR, Park HJ, Son CG . Indirect moxibustion(CV4 and CV8) ameliorates chronic fatigue: a randomized, double-blind, controlled study[J]. J Altern Complement Med, 2013,19(2):134-140
doi: 10.1089/acm.2011.0503
[12] Chen M, Chen R, Xiong J, Chi Z, Sun J, Su T, Zhou M, Yi F, Zhang B . Evaluation of different moxibustion doses for lumbar disc herniation: multicentre randomised controlled trial of heat-sensitive moxibustion therapy[J]. Acupunct Med, 2012,30(4):266-272
doi: 10.1136/acupmed-2012-010142
[13] Zhao B, Wang X, Lin Z, Liu R, Lao L . A novel sham moxibustion device: a randomized, placebo-controlled trial[J]. Complement Ther Med, 2006,14(1):53-60
doi: 10.1016/j.ctim.2005.06.003
[14] Ren XM, Cao JJ, Shen XY, Wang LZ, Zhao L, Wu F, Zhang HM . Preliminary clinical randomized controlled trial on knee osteoarthritis treated with moxibustion[J]. World J Acupunct Moxib, 2012,22(2):28-33
doi: 10.1016/S1003-5257(12)60024-5
[15] Kim SY, Yi SH, Cho JH, Yin CS, Lee H, Park HJ. Heat stimulation on the skin for medical treatment: can it be controlled? JTHER].Kim SY, Yi SH, Cho JH, Yin CS, Lee H, Park HJ. Heat stimulation on the skin for medical treatment: can it be controlled?[J] Altern Complement Med. 2011; 17(6):497-504.
doi: 10.1089/acm.2010.0072
[16] Wang T, Zhang Q, Xue X, Yeung A . A systematic review of acupuncture and moxibustion treatment for chronic fatigue syndrome in China[J]. Am J Chin Med, 2008,36(1):1-24
doi: 10.1142/S0192415X08005540
[17] Guo J . Chronic fatigue syndrome treated by acupuncture and moxibustion in combination with psychological approaches in 310 cases[J]. J Tradit Chin Med, 2007,27(2):92-95
[1] Chiung-Hui Huang, Mei-Ling Yeh, Fang-Pey Chen, Daphne Wu. Low-level laser acupuncture reduces postoperative pain and morphine consumption in older patients with total knee arthroplasty: A randomized placebo-controlled trial. Journal of Integrative Medicine, 2022, 20(4): 321-328.
[2] Keat Lam Ho, Phaik Har Yong, Chee Woon Wang, Umah Rani Kuppusamy, Chek Tung Ngo, Festo Massawe, Zhi Xiang Ng. Peperomia pellucida (L.) Kunth and eye diseases: A review on phytochemistry, pharmacology and toxicology. Journal of Integrative Medicine, 2022, 20(4): 292-304.
[3] Lu Yin, Yun An, Xiao Chen, Hui-xin Yan, Tao Zhang, Xin-gang Lu, Jun-tao Yan. Local vibration therapy promotes the recovery of nerve function in rats with sciatic nerve injury. Journal of Integrative Medicine, 2022, 20(3): 265-273.
[4] Maryam Azimi, Hanieh Niayesh, Mahboobeh Raeiszadeh, Sedigheh Khodabandeh-shahraki. Efficacy of the herbal formula of Foeniculum vulgare and Rosa damascena on elderly patients with functional constipation: A double-blind randomized controlled tria. Journal of Integrative Medicine, 2022, 20(3): 230-236.
[5] Ubiratan Cardinalli Adler, Maristela Schiabel Adler, Ana Elisa Madureira Padula, Livia Mitchiguian Hotta, Amarilysde Toledo Cesar, José Nelson Martins Diniz, Helen de Freitas Santos, Edson Zangiacomi Martinez. Homeopathy for COVID-19 in primary care: A randomized, double-blind, placebo-controlled trial (COVID-Simile study). Journal of Integrative Medicine, 2022, 20(3): 221-229.
[6] Zeinab Vafaeipour, Bibi Marjan Razavi, Hossein Hosseinzadeh. Effects of turmeric (Curcuma longa) and its constituent (curcumin) on the metabolic syndrome: An updated review. Journal of Integrative Medicine, 2022, 20(3): 193-203.
[7] Jia-yi Zhao, Jin Pu, Jian Fan, Xin-yu Feng, Jian-wen Xu, Rong Zhang, Yan Shang. Tanshinone IIA prevents acute lung injury by regulating macrophage polarization. Journal of Integrative Medicine, 2022, 20(3): 274-280.
[8] Marisa Casal. Improving the health and treatment success rates of in vitro fertilization patients with traditional chinese medicine: need for more robust evidence and innovative approaches. Journal of Integrative Medicine, 2022, 20(3): 187-192.
[9] Ning Guo, Fei Wu, Mei Wu, Yuan Wang, Qing Lang, Xiao Lin, Yi Feng. Progress in the design and quality control of placeboes for clinical trials of traditional Chinese medicine . Journal of Integrative Medicine, 2022, 20(3): 204-212.
[10] Xin Wang, Wen-juan Song, Yi Ruan, Bing-chu Li, Can Lü, Nian Huang, Fan-fu Fang, Wei Gu. Core muscle functional strength training for reducing the risk of low-back pain in military recruits: An open-label randomized controlled trial. Journal of Integrative Medicine, 2022, 20(2): 145-152.
[11] Yan-jun Lin, Kun-li Jiao, Bo Liu, Lu Fang, Shu Meng. Antiplatelet and myocardial protective effect of shexiang tongxin dropping pill in patients undergoing percutaneous coronary intervention: A randomized controlled trial. Journal of Integrative Medicine, 2022, 20(2): 126-134.
[12] Hong-xiao Li, Ling Shi, Shang-jie Liang Chen-chen Fang, Qian-qian Xu, Ge Lu, Qian Wang, Jie Cheng, Jie Shen, Mei-hong Shen. Moxibustion alleviates decreased ovarian reserve in rats by restoring the PI3K/AKT signaling pathway. Journal of Integrative Medicine, 2022, 20(2): 163-172.
[13] Peter Bablis, Henry Pollard, Anthony L. Rosner. Stress reduction via neuro-emotional technique to achieve the simultaneous resolution of chronic low back pain with multiple inflammatory and biobehavioural indicators: A randomized, double-blinded, placebo-controlled trial. Journal of Integrative Medicine, 2022, 20(2): 135-144.
[14] Ye-juan Jia, Tian-yu Li, Peng Han, Yu Chen, Li-jia Pan, Chun-sheng Jia. Effects of different courses of moxibustion treatment on intestinal flora and inflammation of a rat model of knee osteoarthritis. Journal of Integrative Medicine, 2022, 20(2): 173-181.
[15] Jose Antonio Castilla-Jimena, Isabel Ruiz-Pérez, Jesús Henares-Montiel. Impact of socioeconomic and health-related factors on consumption of homeopathic and natural remedies in Spain in 2006, 2011 and 2017. Journal of Integrative Medicine, 2022, 20(1): 52-56.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Jin-rong Fu. Establishment of multivariate diagnosis and treatment system of modern gynecology of traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 22-24
[2] Hao Li, Ming-jiang Yao, Wen-ming Zhao, Jie Guan, Lin-lin Cai, Ling Cui. A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment. Journal of Chinese Integrative Medicine, 2008, 6(1): 25-31
[3] Zhi-chun Jin. Problems in establishing clinical guideline for integrated traditional Chinese and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 5-8
[4] SUN Ming-yu, ZUO Jian, DUAN Ji-feng, HAN Jun, FAN Shi-ming, ZHANG Wei, ZHU Li-fang, YAO Ming-hui. Antitumor activities of kushen flavonoids in vivo and in vitro. Journal of Chinese Integrative Medicine, 2008, 6(1): 51-59
[5] Min Cheng, Qiong Feng, Shu-wen Qian, Hui Gao, Cui-qing Zhu. Preliminary assay of p-amyloid binding elements in heart-beneficial recipe. Journal of Chinese Integrative Medicine, 2008, 6(1): 68-72
[6] Ning-qun Wang, Liang-duo Jiang, Zong-xing Li. Research progress in asthma-related quality of life. Journal of Chinese Integrative Medicine, 2008, 6(1): 93-97
[7] Jing-yuan Mao, Chang-xiao Liu, Heng-he Wang, Guang-li Wei , Zhen-peng Zhang, Jie Xing, Wang Xian liang , Ying-fei Bi . Effects of Shenmai Injection on serum concentration and pharmacokinetics of digoxin in dogs with heart failure. Journal of Chinese Integrative Medicine, 2010, 8(11): 1070-1074
[8] Zhi-mei Wang, Bin Zhang. A study on translation of ellipses in Huangdi Neijing from perspective of hermeneutic theory. Journal of Chinese Integrative Medicine, 2010, 8(11): 1097-1100
[9] Gui Yu, Jie Wang. Thinking on building the network cardiovasology of Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(11): 1206-1210
[10] Pedro Saganha João, Doenitz Christoph, Greten Tobias, Efferth Thomas, J. Greten Henry. Qigong therapy for physiotherapists suffering from burnout: a preliminary study. Journal of Chinese Integrative Medicine, 2012, 10(11): 1233-1239
[an error occurred while processing this directive]