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Journal of Chinese Integrative Medicine ›› 2009, Vol. 7 ›› Issue (3): 218-222.doi: 10.3736/jcim20090304

• Original Clinical Research • Previous Articles     Next Articles

Changes of tongue and pulse parameters in 50 lung cancer patients treated with integrated traditional Chinese and Western medicine

 Hai-xia Yana, Yi-qin Wanga, Hui-rong Zhub, Li-hong Zhaoc, Ci-bin Lina, Qi-miao Gonga,Peng-nian Liua   

  1. a School of Basic Medical Sciences, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    b Department of Oncology, Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    c Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
  • Received:2008-09-22 Accepted:2008-12-12 Online:2009-03-20 Published:2009-03-15

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Objective

To observe the changes of tongue and pulse parameters in lung cancer patients after combined treatment with integrated traditional Chinese and Western medicine, and to probe into the application of the tongue and pulse parameters in evaluation of integrated traditional Chinese and Western medicine therapy on lung cancer patients.
Methods

Electropulsograms and tongue pictures of 50 lung cancer patients were examined by TP-Ⅰ digital electropulsography. The tongue and pulse parameters of the patients, including the indexes of moistness and dryness, thinness and thickness, fissure, swollenness and emaciation, greasiness and likeness of curd, and power spectral ratios (PSRs) 1, 2, 3, 4 and cepstrum spectral ratios (CSRs) 1, 2, 3, 4, were observed after 1- and 2-month treatment with Yifei Kangliu Oral Liquid (a compound traditional Chinese herbal medicine) plus chemotherapy, respectively. The above parameters of the lung cancer patients were compared before and after the treatment.
Results

PSR1 increased, while PSR2 decreased significantly after 1- and 2-month treatment as compared with before treatment (P<0.05). PSR1 decreased, while PSR2 increased after 2-month treatment as compared with after 1-month treatment (P<0.05). PSR4 after 1-month treatment was lower than before treatment (P<0.05). The tongue parameters including the indexes of moistness and dryness, and greasiness and likeness of curd increased significantly after 1- and 2-month treatment as compared with before treatment (P<0.05). The index of thinness and thickness decreased, while the index of fissure increased significantly after 1-month treatment as compared with before treatment (P<0.05).
Conclusion

Tongue and pulse parameters can be regarded as one of reference indexes in evaluation of integrated traditional Chinese and Western medicine therapy on lung cancer patients.

Key words: Tongue color, Tongue coating, Sphygmogram, Lung cancer, Treatment outcome, Outcome assessment

Table 1

Power spectral ratios of the lung cancer patients before and after treatment (x±s)"

Observation time n PSR1 PSR2 PSR3 PSR4
Before treatment 50 0.49±0.05 0.31±0.04 0.11±0.02 0.10±0.02
After 1-month treatment 50 0.58±0.06* 0.23±0.05* 0.10±0.03 0.08±0.02*
After 2-month treatment 50 0.54±0.07*△ 0.26±0.06*△ 0.26±0.06 0.09±0.03*

Table 2

Cepstrum spectral ratios of the lung cancer patients before and after treatment (x±s)"

Observation time n CSR1 CSR2 CSR3 CSR4
Before treatment 50 0.208±0.010 0.199±0.004 0.198±0.005 0.396±0.005
After 1-month treatment 50 0.211±0.016 0.198±0.005 0.197±0.006 0.395±0.007
After 2-month treatment 50 0.207±0.007 0.200±0.002 0.200±0.003 0.397±0.005

Table 3

Tongue parameters of the lung cancer patients before and after treatment (x±s)"

Observation time n Moistness
and dryness		 Fissure Thinness and
thickness		 Swollenness
and emaciation		 Greasiness and
likeness of curd
Before treatment 50 0.77±0.36 0.47±0.26 0.34±0.32 0.82±0.16 0.54±0.26
After 1-month treatment 50 0.96±0.20* 0.52±0.22* 0.21±0.30* 0.84±0.12 0.67±0.22*
After 2-month treatment 50 0.92±0.27* 0.47±0.23 0.28±0.26 0.83±0.15 0.67±0.24*
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