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Journal of Chinese Integrative Medicine ›› 2009, Vol. 7 ›› Issue (11): 1096-1099.doi: 10.3736/jcim20091115

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Ayurvedic medicines in treatment of cancer

Sunyana Jaina,Vikrant Gillb,Neeru Vasudevac,Neelam Singlaa   

  1. a Department of Pharmacy, Advance Institute of Technology, Dehli-Mathura Road, Dist. Palwal 121102，Haryana, India
    b Ranbaxy Laboratories Ltd, Clinical Pharmacology and Pharmacokinetic Department, Gurgaon 122001, Haryana, India
    c Department of Pharmaceutical Sciences，Guru Jambheshwar University of Science and Technology, Hissar 125001， Haryana, India
  • Received:2009-07-09 Accepted:2009-08-27 Online:2009-11-20 Published:2009-11-15
  • Contact: Sunyana Jain E-mail:sunyanajain@rediffmail.com
  • Supported by:
    Paste of Capparis spinosa, Capparis sepiari, Agati grandiflora and Lagenaria vulgaris is applied locally for treatment of Kapaja granthi [25].;Paste of Glycyrrhiza glabra, Eugenia jambolana, Terminalia arjuna and Calamus rotang isapplied externally for the treatment of Paittika granthi [25].;This drug is prescribed in treatment of granthi [12].;Mixture of Helloborus niger, Tinospora cordifolia, Clerodendron serratum, Aegle marmelos, Hoya viridiflora and Elephantopus scber is applied locally for the treatment of vatika granthi [25].

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Key words: Medicine, Ayurvedic, Neoplasma, Phytotherapy

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No. Name of herb Method and use Common name
1 Allium sativum Linn.
(Liliaceae)		 Solid extract is given and oil is applied on infected area. Water soluble compounds present are mainly responsible for anticancer activity. Useful in human breast, colon and prostrate cancers[15]. Lahsun
2 Abrus precatorius Linn.
(Fabaceae)		 Leaf decoction and root powder are applied. It is useful for the treatment of Yoshida sarcoma, fibrosarcoma and ascites tumor cells[16]. Indian liquorice
3 Alstonia scholaris R. Brown.
(Apocyanaceae)		 Leaf extract is given. It is useful in the treatment of HIS human sarcoma and benzopyrene-induced stomach carcinoma[17]. Chatiun
4 Asparagus racemosus Willd.
(Liliaceae)		 Powder is given and is used in treatment of human epidermoid
carcinoma[18].		 Shatavari
5 Andrographis paniculata Nees.
(Acanthaceae)		 Powder or juice of leaf or stem is given and useful in treatment of various cancers[19]. Kalmegh
6 Amorphopallus campanulatus
Roxb. (Araceae)		 The mature tuber is first burnt and then mixed with butter and jaggary and applied externally for tumour destruction[20]. Konyaku
7 Berberis aristata DC.
(Berberidaceae)		 Powder is given and useful in the treatment of human epidermal carci-noma of the nasopharynx and N-nitrosodiethlyamine-induced carcinogenesis[21]. Chitra
8 Barleria prionitis Linn.
(Acanthaceae)		 The oil prepared with whole plant is applied externally during acute
stages of cysts in blood vessels[22].
9 Basella rubra Linn.
(Chenopodiaceae)		 The leaves are ground with sour buttermilk. Add some salt and indicated for Abruda[23]. Pothi, Valchibhagi
10 Baliospermum montanumWilld.
(Euphorbiaceae)		 The paste consisting of Baliospermum montanum, Plumbago zeylanica, Euphorbia neriifolia, Calotropis procera, Semecarpus anacardium and jaggery applied to tumors[12]. Jamalgota
11 Boswellia serrata Roxb.
(Burseraceae)		 Bark decoction, gum resins are given internally and oil is applied externally on tumor. It is useful in the treatment of human epidermal carci-noma of nasophyranx, leukemia and brain tumors[18, 24]. Kundur
12 Curcuma domestica Val.
(Zingiberaceae)		 The Curcuma domestica powder in combination with Symplocos racemosa and Soymida febrifuga are mixed with honey and used exter-nally[12, 20]. Haladi
13 Capparis spinosa Linn.
(Caparidaceae)		 Paste of Capparis spinosa, Capparis sepiari, Agati grandiflora and Lagenaria vulgaris is applied locally for treatment of Kapaja granthi[25]. Ber
14 Euphoria hirta Linn.
(Euphorbiaceae)		 Powder and liquid extracts are given. Used to cure Freund virus leuke-mia[26]. Nahanidudheli
15 Eugenia jambolana Lamk. (Myrtaceae) Paste of Glycyrrhiza glabra, Eugenia jambolana, Terminalia arjuna and Calamus rotang isapplied externally for the treatment of Paittika granthi[25]. Jamun
16 Elephantopus scaber Linn.
(Compositae)		 Fine paste of leaves of Ficus glomerata, Tectona grandis and Elephantopus scaber mixed with honey is applied locally for treatment of pittaja arbuda[25]. Gobhi
17 Ficus bengalensis Linn.
(Urticaceae)		 Ficus bengalensis and Sausserea lappa mixture is applied to decrease tumor growth on bones[26]. Phagwari
18 Flacourtia romantchi L’ Her.
(Flacourtiaceae)		 The paste of Flacourtia romantchi, Cassia fistula and Capparis sepiaria is recommended for kaphaja tumours[12]. Bhanber
19 Hygrophila spinosa Linn.
(Acanthaceae)		 Seed powder and liquid extract are given to cure Daltons lymphoma and Ehrich ascites carcinoma of the nasophyranx[27, 28].
20 Madhuca indica Gmel.
(Sapotaceae)		 The paste is prepared from bark of Madhuca indica, Syzygium cumini and Salix caperaand prescribed for local application[12].
21 Moringa oleifera Lam.
(Moringaceae)		 The paste of Moringa olifera seeds, Solanum xanthocarpum, Sinapis dichotoma, Holarrhena antidysentrica and Nerium odorum roots prepared with butter milk is used for arbudatumors[29, 30]. Mungna
22 Oxoxylum indicum Linn.
(Bignoniaceae)		 This drug is prescribed in treatment of granthi[12]. Podaval, Tetu
23 Proscopis cineraria Linn.
(Mimosaceae)		 The paste made of Proscopis cineraria seeds, Raphanus sativa, Moringa oleifera, barley and mustard with buttermilk are applied locally to disintegrate cysts[22]. Chhikura
24 Pandanus odoratissimum Lem.
(Pandanaceae)		 A paste of Pandanus odoratissimum and sugar are applied externally on tumors[12]. Kewoda.
25 Pterospermum acerifolium
Willd. (Sterculiaceae)		 The flowers of Pterospermum acerifolium are mixed with sugar and applied externally[22]. Kanakchamka
26 Phyllanthus niruri Linn.
(Euphorbiaceae)		 Aqueous extract of Phyllanthus niruri is applied locally for the treatment of cancer[25]. Buinowala.
27 Raphanus sativus Linn.
(Brassicaceae)		 Local application of Raphanus sativus paste with radish ash is effective in Kaphaja arbuda[22] Black radish
28 Ricinus communis Linn.
(Euphorbiaceae)		 Paste of Ricinus communis, Benincase cerifera, Cucumis memordica, Cocus nucifera and Eranda beeja along with buttermilk or milk is applied externally for the treatment of Vataja arbuda[31]. Castor oil
29 Tinospora cordifolia Miers.
(Menispermaceae)		 Mixture of Helloborus niger, Tinospora cordifolia, Clerodendron serratum, Aegle marmelos, Hoya viridiflora and Elephantopus scber is applied locally for the treatment of vatika granthi[25]. Gulvel
30 Terminalia arjuna W & Arn.
(Combretaceae)		 Bark powder is effective in kappha and pita[20]. Arjun
31 Vitis vinifera Linn.
(Vitaceae)		 The mixture of Terminalia chebula, grape juice and sugarcane juice is used for the treatment of cancer[32]. Vine
32 Zingiber officinalis Rosc.
(Zingiberaceae)		 Rhizome powder is given to cure cancer. Pungent principles present are responsible for anticancer activity[22]. Sunth
[1] Reddy L, Odhav B, Bhoola KD . Natural products for cancer prevention: a global perspective[J]. Pharmacol Ther, 2003,99(1):1-13
doi: 10.1016/S0163-7258(03)00042-1 pmid: 12804695
[2] Hartwell L . Plants used against cancer. A survey[J]. Lloydia, 1971,32(1):78-107
doi: 10.1016/0024-3205(69)90192-1 pmid: 5788771
[3] Srivastava V, Negi AS, Kumar JK, Gupta MM, Khanuja SP . Plant-based anticancer molecules: a chemical and biological profile of some important leads[J]. Bioorg Med Chem, 2005,13(21):5892-5908
doi: 10.1016/j.bmc.2005.05.066 pmid: 16129603
[4] Boik J. Conducting research on natural agents. In: Boik J. Cancer and natural medicine: A textbook of basic science and clinical research. Minnesota: Oregon Medical Press. 1996: 176-187.
[5] Farnsworth NR, Akerele O, Bingel AS, Soejarto DD, Guo Z . Medicinal plants in therapy[J]. Bull World Health Organ, 1985,63(6):965-981
[6] Cragg GM, Newman DJ, Snader KM . Natural products in drug discovery and development[J]. J Nat Prod, 1997,60(1):52-60
doi: 10.1021/np9604893
[7] Sastry JLN . Introduction to oncology(cancer) in Ayurveda[M]. Varanasi: Chaukhambha Orientalia, 2001: 1
[8] Balachandran P, Govindarajan R . Cancer an Ayurvedic perspective[J]. Pharmacol Res, 2005,51(1):19-30
doi: 10.1016/j.phrs.2004.04.010 pmid: 15519531
[9] Pandey G . Anticancer herbal drugs of India: with special reference to Ayurveda[M]. New Delhi: Sri Satguru Publications, 2002: 18-121
[10] Treadway S . An Ayurvedic herbal approach to a healthy liver[J]. Clin Nutr Insights, 1998,6(16):1-3
[11] Sharma PV . Caraka samhita. Including critical notes(Vol 1-4)[M]. Varanasi: Chaukhambha Orientalia, 1981,( Vol 1-4):544
[12] Bhishagratna KL.Sushruta Samhita , English translation, Nidana-sthana, Sarira-sthana, Chikitsa-sthana and Kalpa-sthana(Vol 2)[M]. Varanasi: Chowkhamba Sanskrit Series Office, 1991,( Vol 2):571
[13] Acharaya PK.Encyclopedia of Hindu architecture[M].New Dehli: Oriental Book Reprints Co, 1979:
[14] Badmaev V, Majeed M . Effects of Ayurvedic herbs. Health Supplement Retailer Magazine. 1995: 22-25.
[15] Hu X, Cao BN, Hu G, He J, Yang DQ, Wan YS . Attenuation of cell migration and induction of cell death by aged garlic extract in rat sarcoma cells[J]. Int J Mol Med, 2002,9(6):641-643
[16] Subba Reddy VV, Sirsi M . Effect of Abrus precatorius Linn. on experimental tumours[J]. Cancer Res, 1969,29(7):1447-1451
doi: 10.1002/1097-0142(196906)23:6<1436::AID-CNCR2820230627>3.0.CO;2-6 pmid: 5799161
[17] Jagetia GC, Baliga MS, Venkatesh P . Effect of Sapthaparna(Alstonia scholaris Linn) in modulating the benzo(a)pyrene-induced forestomach carcinogenesis in mice[J]. Toxicol Lett, 2003,144(2):183-193
doi: 10.1016/S0378-4274(03)00205-4
[18] Dhar ML, Dhar MM, Dhawan BN, Mehrotra B, Ray C . Screening of Indian plants for biological activity[J]. Indian J Exp Biol, 1968,( 6):232
[19] Trivedi NP, Rawal UM . Hepatoprotective and antioxidant property of Andrographis paniculata(Nees) in BHC-induced liver damage in mice[J]. Indian J Exp Biol, 2001,39(1):41-46
[20] Prasad GC . Studies on cancer in Ayurveda and its management[J]. J Res Ayur Sid, 1987,3(4):146-167
[21] Anis KV, Rajeshkumar NV, Kuttan R . Inhibition of chemical carcinogenesis by berberine in rats and mice[J]. J Pharm Pharmacol, 2001,53(5):763-768
doi: 10.1211/0022357011775901 pmid: 11370717
[22] Kinjavadekara RS. Astanga sangraha[M]. New Delhi: Uppal Publishing House,1998:
[23] Singh RH . An assessment of Ayurvedic concept of cancer and a new paradigm of anticancer treatment in Ayurveda[J]. J Altern Complemen Med, 2002,8(5):609-614
doi: 10.1089/107555302320825129
[24] Hostanska K, Daum G, Saller R . Cytostatic and apoptosis-inducing activity of boswellic acids toward malignant cell lines in vitro[J]. Anticancer Res, 2002,22(5):2853-2862
[25] 25Dash B, Kashyap L . Diagnosis and treatment of galaganda, gandamala, apaci, granthi and arbuda. In: Dash B, Kashyap L. Diagnosis and treatment of diseases in Ayurveda. New Delhi: Concept Publishing Company. 1987: 437.
[26] Murthy KRS.Bhavaprakasa of bhavamisra, Madhya and Uttara Khanda[M].Varanasi: Krishnadas Academy , 2001: Vol II
[27] Maiti B . Antineoplastic effects of the root extract of Hygrophila spinosa. Calcutta: Proceedings of the International Conference on Current Progress in Medicinal and Aromatic Plant Research. 1994: 135-140.
[28] Mazumdar UK, Gupta M, Maiti S, Mukherjee D . Antitumour activity of Hygrophila spinosa on Ehrlich ascites carcinoma and sarcoma-180 induced mice[J]. Indian J Exp Biol, 1997,35(5):473-477
[29] Dhawan BN, Dubey MP, Mehrotra BN, Rastogi RP, Tandon JS . Screening of Indian plants for biological activity: part Ⅸ.[J]. Indian J Exp Biol, 1980,18(6):594-606
doi: 10.1016/0019-2791(71)90395-8 pmid: 914326
[30] Bharali R, Tabassum J, Azad MR . Chemomodulatory effect of Moringa oleifera Lam. on hepatic carcinogen metabolising enzymes, antioxidant parameters and skin papillomagenesis in mice[J]. Asian Pac J Cancer Prev, 2003,4(2):131-139
[31] 31Singhal GD, Singh LM . The management of glandular swellings, cervical lymphadenopathy, tumours and goiters. In: Singhal GD, Singh LM. Operative considerations in ancient Indian surgery based on Susruta Samhita, Cikitsa sthana. Varanasi: Singhal Publications. 1982: 339-356.
[32] Jang M, Cai L, Udeani GO, Slowing KV, Thomas CF, Beecher CW, Fong HH, Farnsworth NR, Kinghorn AD, Mehta RG, Moon RC, Pezzuto JM . Cancer chemopreventive activity of resveratrol, a natural product derived from Grapes[J]. Science, 1997,275(5297):218-220
doi: 10.1126/science.275.5297.218 pmid: 8985016
[33] Office of Alternative Medicine.Office of alternative medicine workshop on the collection of clinical research data relevant to alternative medicine and cancer[M].Bethesda: Office of Alternative Medicine, 1994:
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