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Journal of Chinese Integrative Medicine ›› 2011, Vol. 9 ›› Issue (10): 1088-1093.doi: 10.3736/jcim20111009

• Original Clinical Research • Previous Articles     Next Articles

Effects of Tuina and Chinese patent drug Shuxuetong injection on deep venous thrombosis and functional rehabilitation after total knee arthroplasty

Jun-lin Hu, Gui-lin Ouyang, Da-peng Han(), Qing Xia, Yong He, Zheng Huang, Fei Zhu, Song-tao Sun   

  1. Department of Orthopaedic Surgery, Guanghua Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 200052, China
  • Received:2011-01-25 Accepted:2011-07-31 Online:2011-10-20 Published:2011-10-15
  • Contact: Han Da-peng E-mail:han_dp@126.com

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Objective: To evaluate the efficacy of Tuina and Chinese patent drug Shuxuetong injection in preventing patients undergoing total knee arthroplasty from deep venous thrombosis and in functional rehabilitation.

Methods: A total of 120 patients with diagnosed rheumatoid arthritis in the Department of Orthopaedic Surgery, Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine in China were enrolled for this study. The patients underwent total knee arthroplasty and were divided into treatment group (n=60) and control group (n=60) after surgery. Patients in the control group received conventional rehabilitation training, including using a continuous passive motion machine and training of muscle contractions of the lower limb. Patients in the treatment group were administered Shuxuetong injection and Tuina based on the conventional rehabilitation training. The course of treatment lasted for 2 weeks. Hospital for Special Surgery (HSS) knee score, rate of deep venous thrombosis and range of motion of the knee joint were evaluated before and after treatment.

Results: There was no significant difference in HSS knee score and range of motion as compared before and after treatment in two group (P>0.05). The rate of deep venous thrombosis of the treatment group was 13.33%, which was lower than 20% of the control group (P<0.05).

Conclusion: Tuina combined with Shuxuetong injection treatment can prevent deep venous thrombosis in patients with rheumatoid arthritis after total knee arthroplasty.

Key words: venous thrombosis, arthroplasty, replacement, knee, Tuina, arthritis, rheumatoid, Chinese patent drugs, controlled clinical trial

Table 1

Basic condition ($\overline{x}$±s)"

Bisic condition Treatment group (n=60) Control group (n=60)
Gender
Male (case) 14 16
Female (case) 46 44
Age ($\overline{x}$±s, years) 49.6±3.5 50.7±2.7
Weight ($\overline{x}$±s, kg) 55.6±1.9 55.8±2.6
Operation time ($\overline{x}$±s, min) 63±7 62±8
Amount of bleeding ($\overline{x}$±s, mL) 415±115 405±120

Figure 1

Flow chart of this trial"

Table 2

Range of motion and HSS knee score of patients in two group ($\overline{x}$±s)"

Group n HSS knee score Range of motion (°)
Before operation After operation Before operation After operation
Treatment 60 61.79±7.48 61.93±7.89 64.09±6.13 110.25±15.79
Control 60 87.45±4.81 83.23±6.92 63.97±5.44 100.16±14.76
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