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Clinical practice guidelines for the diagnosis and treatment of atopic dermatitis with integrative traditional Chinese and Western medicine

Xin-ran Du a, Meng-yi Wu a, Mao-can Tao b, Ying Lin c, Chao-ying Gu d, Min-feng Wu e, Yi Cao b, Da-can Chen c, Wei Li d, Hong-wei Wang e, Ying Wang f, Yi Wang a, Han-zhi Lu a, Xin Liu a, Xiang-fei Su g, Fu-lun Li a   

  1. a Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
    b Department of Dermatology, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou 310060 Zhejiang Province, China
    c Department of Dermatology, Guangdong Provincial Hospital of Chinese Medicine, Guangzhou 510120 Guangdong Province, China
    d Department of Dermatology, Huashan Hospital, Fudan University, Shanghai 200040, China
    e Department of Dermatology, Huadong Hospital, Fudan University, Shanghai 200040, China
    f School of Public Health, Fudan University, Shanghai 200032, China
    g Standardisation Office, China Association of Chinese Medicine, Beijing 100029, China
  • Received:2025-05-24 Accepted:2025-07-30 Published:2025-08-23
  • Contact: Fu-lun Li, PhD; E-mail address: drlifulun@163.com. Xiang-fei Su, PhD; E-mail address: suxiangfei2011@163.com

Traditional Chinese medicine (TCM) is a well-accepted therapy for atopic dermatitis (AD). However, there are currently no evidence-based guidelines integrating TCM and Western medicine for the treatment of AD, limiting the clinical application of such combined approaches. Therefore, the China Association of Chinese Medicine initiated the development of the current guideline, focusing on key issues related to the use of TCM in the treatment of AD. This guideline was developed in accordance with the principles of the guideline formulation manual published by the World Health Organization. A comprehensive review of the literature on the combined use of TCM and Western medicine to treat AD was conducted. The findings were extensively discussed by experts in dermatology and pharmacy with expertise in both TCM and Western medicine. This guideline comprises 23 recommendations across seven major areas, including TCM syndrome differentiation and classification of AD, principles and application scenarios of TCM combined with Western medicine for treating AD, outcome indicators for evaluating clinical efficacy of AD treatment, integration of TCM pattern classification and Western medicine across disease stages, daily management of AD, the use of internal TCM therapies and proprietary Chinese medicines, and TCM external treatments.

Key words: Atopic dermatitis, Clinical practice guidelines, Integrative medicine, Traditional Chinese medicine, Evidence-based medicine

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