Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2008, Vol. 6 ›› Issue (9): 971-974.doi: 10.3736/jcim20080920

• Literature Review • Previous Articles     Next Articles

Conception of inner ear blood labyrinth barrier and progress in research of traditional Chinese medicine

Ming Ge1(), Tian-shu Xu1, Xia Gao2   

  1. 1. Department of Traditional Chinese Medicine, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiang¬su Province 210008, China;
    2. Department of Otolaryngology, Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu Province 210008, China
  • Received:2008-02-27 Online:2008-09-20 Published:2008-09-15

Key words: blood labyrinth barrier, Xuan-fu theory, therapy of traditional Chinese medicine

CLC Number: 

  • R322.9+23
[1] Juhn SK, Hunter BA, Odland RM . Blood-labyrinth barrier and fluid dynamics of the inner ear[J]. Int Tinnitus J, 2001,7(2):72-83
pmid: 14689642
[2] Sakagami M, Matsunaga T, Hashimito PH , et al. Fine structure and permeability of capillaries in the stria vascular and spiral ligament of the inner ear of the guinea pig[J]. Cell Tissue Res, 1982,226(3):511-522
[3] Kroll RA, Neuwelt EA . Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means[J]. Neurosurgery, 1998,42(5):1083-1099
doi: 10.1097/00006123-199805000-00082 pmid: 9588554
[4] Sakagami M, Sano M, Matsunaga T . Ultrastructural study of the effect of acute hypertension on the stria vascularis and spiral ligament[J]. Acta Otolaryngol, 1984,97(1-2):53-61
[5] Luciano L, Reiss G, Iurato S , et al. The junctions of the spindle-shaped cells of the stria vascularis: a link that completes the barrier between perilymph and endolymph[J]. Hear Res, 1995,85(1-2):199-209
doi: 10.1016/0378-5955(95)00047-8
[6] Juhn SK, Rybak LP, Prado S . Nature of blood-labyrinth barrier in experimental conditions[J]. Ann Otol Rhinol Laryngol, 1981,90(2 Pt 1):135-141
doi: 10.1177/000348948109000208 pmid: 7224511
[7] Zhang ZJ, Saito T, Kimura Y , et al. Disruption of mdr1a p-glycoprotein gene results in dysfunction of blood-inner ear barrier in mice[J]. Brain Res, 2000,852(1):116-126
doi: 10.1016/S0006-8993(99)02223-4
[8] Liu WS. Su wen xuan ji yuan bing shi. In: Song NG. All medical books of Liu wan-su[M]. Beijing: China Press of Traditional Chinese Medicine,2006: 99-102
刘完素 . 素问玄机原病式. 见: 宋乃光. 刘完素医学全书[M]. 北京: 中国中医药出版社,2006: 99-102
[9] Zheng GQ, Huang PX . Xuanfu theory on microcirculation and channel of ion[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 2003,9(4):13-14
郑国庆, 黄培新 . 玄府与微循环和离子通道[J]. 中国中医基础医学杂志, 2003,9(4):13-14
[10] Zhang XY, Wang JB . The effect of obstruction with microcirculation in inner ear of mice to the permeability of blood labyrinth barrier[J]. Zhonghua Er Bi Yan Hou Ke Za Zhi, 2000,35(5):339-341
doi: 10.3760/j.issn:1673-0860.2000.05.005
张学渊, 汪吉宝 . 豚鼠内耳微循环障碍对血迷路屏障通透性的影响[J]. 中华耳鼻咽喉科杂志, 2000,35(5):339-341
doi: 10.3760/j.issn:1673-0860.2000.05.005
[11] Murphy TP . Microvascular sensorineural hearing loss[J]. Am J Otol, 1991,12(2):88-92
[12] Su ZL . The theory of channel of ion and clinical practice of otolaryngology—cephalothorax surgery[J]. Zhonghua Er Bi Yan Hou Ke Za Zhi, 2000,35(4):310-312
doi: 10.3760/j.issn:1673-0860.2000.04.035
苏振伦 . 离子通道理论与耳鼻咽喉——头颈外科临床实践[J]. 中华耳鼻咽喉科杂志, 2000,35(4):310-312
doi: 10.3760/j.issn:1673-0860.2000.04.035
[13] Yu H . The experiment study of effect to inner ear of mice by Salvia miktiorrhiza and glycerin[J]. Kunming Yi Xue Yuan Xue Bao, 1994,15(4):12
余宏 . 丹参加甘油对豚鼠内耳作用的实验研究[J]. 昆明医学院学报, 1994,15(4):12
[14] Zheng GQ . The microcirculation mechanism of Xuanfu theory and Jia Wei Tong Qi San in removing obstacles from Xuanfu—the academic experience of Professor Zhang Zhiyuan(1)[J]. Zhong Yi Yao Xue Kan, 2006,24(1):18-20
doi: 10.3969/j.issn.1673-7717.2006.01.008
郑国庆 . 耳科玄府说及加味通气散开通玄府的微循环机制——张志远学术经验系列(一)[J]. 中医药学刊, 2006,24(1):18-20
doi: 10.3969/j.issn.1673-7717.2006.01.008
[15] Ge YH . The discussion of syndrome differentiation treatment of hearing loss by nine methods[J]. Beijing Zhong Yi Yao Da Xue Xue Bao, 1994,17(5):53-55
葛英华 . 浅谈耳聋证治九法[J]. 北京中医药大学学报, 1994,17(5):53-55
[16] Ge H . Exploration of the connection between audition loss degree of sudden deafness and syndrome differentiation[J]. Nantong Yi Xue Yuan Xue Bao, 1999,19(2):231
葛灏 . 突发性耳聋听力损失程度与中医辨证分型关系初探[J]. 南通医学院学报, 1999,19(2):231
[17] Fu XD, Ge H . Approach on relationship of syndrome differentiation typing with microcirculation of nailfold and hearing in sudden deafness[J]. Zhongguo Zhong Xi Yi Jie He Er Bi Yan Hou Ke Za Zhi, 2000,8(4):170-172
傅晓东, 葛灏 . 突发性耳聋听力、甲襞微循环与中医辨证关系初探[J]. 中国中西医结合耳鼻咽喉科杂志, 2000,8(4):170-172
[1] Xing-jiang Xiong, Jie Wang. Experience of diagnosis and treatment of exogenous high-grade fever. Journal of Chinese Integrative Medicine, 2011, 9(6): 681-687.
Full text



[1] Wei-xiong Liang. Problems-solving strategies in clinical treatment guideline for traditional Chinese medicine and integrative medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 1-4
[2] Zhao-guo Li. Discussion on English translation of commonly used sentences in traditional Chinese medicine: part one. Journal of Chinese Integrative Medicine, 2008, 6(1): 107-110
[3] Jun Hu, Jian-ping Liu. Non-invasive physical treatments for chronic/recurrent headache. Journal of Chinese Integrative Medicine, 2008, 6(1): 31
[4] Xue-mei Liu, Qi-fu Huang, Yun-ling Zhang, Jin-li Lou, Hong-sheng Liu, Hong Zheng. Effects of Tribulus terrestris L. saponion on apoptosis of cortical neurons induced by hypoxia-reoxygenation in rats. Journal of Chinese Integrative Medicine, 2008, 6(1): 45-50
[5] . Uniform requirements for manuscripts submitted to biomedical journals: Writing and editing for biomedical publication (Chinese version, part two). Journal of Chinese Integrative Medicine, 2010, 8(11): 1001-1005
[6] Daniel Weber, Janelle M Wheat, Geoffrey M Currie. Inflammation and cancer: Tumor initiation, progression and metastasis,and Chinese botanical medicines. Journal of Chinese Integrative Medicine, 2010, 8(11): 1006-1013
[7] Hong Liu , Guo-liang Zhang, Li Shen , Zhen Zeng, Bao-luo Zhou, Cheng-hai Liu, Guang Nie . Application and evaluation of a pseudotyped virus assay for screening herbs for anti-H5Nl avian influenza virus. Journal of Chinese Integrative Medicine, 2010, 8(11): 1036-1040
[8] Zhao-guo Li . A discussion of English translation of 1995 and 1997 Chinese National Standards of Traditional Chinese Medical Terminologies for Clinical Diagnosis and Treatment. Journal of Chinese Integrative Medicine, 2010, 8(11): 1090-1096
[9] Rui Jin, Bing Zhang. A complexity analysis of Chinese herbal property theory: the multiple formations of herbal property (Part 1). Journal of Chinese Integrative Medicine, 2012, 10(11): 1198-1205
[10] Hui-min Liu, Xian-bo Wang, Yu-juan Chang, Li-li Gu. Systematic review and meta-analysis of randomized controlled trials of integrative medicine therapy for treatment of chronic severe hepatitis. Journal of Chinese Integrative Medicine, 2012, 10(11): 1211-1228