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Journal of Chinese Integrative Medicine ›› 2010, Vol. 8 ›› Issue (7): 641-644.doi: 10.3736/jcim20100707

Special Issue: Acupuncture & Moxibustion

• Original Clinical Research • Previous Articles     Next Articles

Acupuncture versus metoclopramide in treatment of postoperative gastroparesis syndrome in abdominal surgical patients: A randomized controlled trial

Bao-mu Sun,Ming Luo,Sheng-bing Wu, Xiao-xia Chen, Meng-chao Wu   

  1. Department of Integrated Traditional Chinese and Western Medicine, Eastern Hepatobiliary Surgical Hospital, Second Military Medical University, Shanghai 200438, China
  • Received:2009-11-12 Online:2010-07-20 Published:2010-07-15
  • Contact: Ming Luo E-mail:luoming6425@sohu.com

Background

Postoperative gastroparesis syndrome (PGS) is a common complication after abdominal surgery in patients with primary liver cancer. However, surgeons usually do not have effective treatment for them.
Objective

To explore the effects of acupuncture applied to Zusanli and other acupoints on PGS in patients after abdominal surgery.
Design, setting, participants and interventions

Sixty-three PGS patients of abdominal surgery, from Eastern Hepatobiliary Surgical Hospital, were randomized into acupuncture group (32 cases) and metoclopramide group (31 cases). The patients in acupuncture group were treated with acupuncture applied to Zusanli and other acupoints once a day, while the patients in metoclopramide group were intramuscularly injected 20 mg metoclopramide three times a day.
Main outcome measures

 Volume of gastric drainage, number of treatment and cure rate in the two groups were measured and evaluated.
Results

Acupuncture and metoclopramide could significantly reduce gastric drainage volume. In acupuncture group, the cure rate was 90.6% and the number of treatment was 6.58±4.26, while in metoclopramide group, the cure rate and the number of treatment were 32.3% and 10.13±3.60 respectively. There were significant differences in gastric drainage volume, cure rate and number of treatment between the two groups (P<0.05, P<0.01).
Conclusion

Acupuncture is a good treatment for PGS, with fewer treatments, high cure rate and rapid effect.

Key words: Acupuncture therapy, Abdominal neoplasms, Gastroparesis, Randomized controlled trial

Figure 1

Flow diagram of this randomized trial"

[1] Liu W . Experience of diagnosis and treatment of gastric atony after gastric operations[J]. Shanxi Yi Ke Da Xue Xue Bao, 2001,32(5):448-449
doi: 10.3969/j.issn.1007-6611.2001.05.037
刘玮 . 胃手术后胃无力症诊治体会[J]. 山西医科大学学报, 2001,32(5):448-449
doi: 10.3969/j.issn.1007-6611.2001.05.037
[2] Yang WL, Zhao G, Zhang XC, Li G . Clinical analysis of postsurgical gastroparesis syndrome after gastrectomy[J]. Zhonghua Wei Chang Wai Ke Za Zhi, 2002,5(4):249-251
杨维良, 赵刚, 张新晨, 李刚 . 胃切除术后残胃胃轻瘫综合征的临床总结[J]. 中华胃肠外科杂志, 2002,5(4):249-251
[3] Wu JP, Qiu FZ. Huang Jiasi surgery(Sixth ed)[M]. Beijing: People’s Medical Publishing House, 2005,( Sixth ed)
吴阶平, 裘法祖 . 黄家驷外科学(第6版)[M]. 北京: 人民卫生出版社, 2005,( 第6版)
[4] Qin XY . Gastrointestinal motility disorders after subtotal gastrectomy[J]. Zhongguo Shi Yong Wai Ke Za Zhi, 1999,19(6):325-326
秦新裕 . 胃大部切除术后胃肠动力紊乱[J]. 中国实用外科杂志, 1999,19(6):325-326
[5] Ren JJ, Li TP, Wang HL, Zhang JY . Clinical analysis of postsurgical gastroparesis syndrome after cholecystectomy: a report of 16 cases[J]. Fu Bu Wai Ke, 2003,16(4):238
任建军, 李太品, 王弘略, 张金银 . 胆囊切除术后胃轻瘫综合征的诊治(附16例报告)[J]. 腹部外科, 2003,16(4):238
[6] Tang WL, Bai P . Diagnosis and treatment of postsurgical gastroparesis syndrome after subtotal gastrectomy[J]. Shaanxi Yi Xue Za Zhi, 2005,34(6):673-674
doi: 10.3969/j.issn.1000-7377.2005.06.011
唐文龙, 白鹏 . 胃大部切除术后残胃排空障碍的诊断和治疗[J]. 陕西医学杂志, 2005,34(6):673-674
doi: 10.3969/j.issn.1000-7377.2005.06.011
[7] Qin XY . Study progress on postsurgical gastroparesis syndrome[J]. Zhonghua Wei Chang Wai Ke Za Zhi, 2002,5(4):243-244
秦新裕 . 手术后胃轻瘫综合征的研究进展[J]. 中华胃肠外科杂志, 2002,5(4):243-244
[8] Liu H, Huang TC, Cai YK, Zhang HK . Gastroparesis after abdominal operation: a clinical analysis of 16 cases[J]. Zhongguo Lin Chuang Yi Xue, 2003,10(3):297-298
刘辉, 黄陶承, 蔡元坤, 张厚康 . 腹部手术后胃轻瘫的原因及诊治(附16例报告)[J]. 中国临床医学, 2003,10(3):297-298
[9] Liu FL, Qin XY . Clinical analysis of 20 cases with postsurgical gastroparesis syndrome after radical subtotal gastrectomy[J]. Zhonghua Wei Chang Wai Ke Za Zhi, 2002,5(4):245-248
刘风林, 秦新裕 . 根治性胃大部切除术后胃轻瘫综合征的回顾性研究[J]. 中华胃肠外科杂志, 2002,5(4):245-248
[10] Yang CM, Zhang XR, Mao GP . Gastric electrogram activity after medium frequency electric stimulation at Zusanli acupoint on healthy volunteers[J]. Zhonghua Li Liao Za Zhi, 2001,24(1):33
杨春敏, 张秀荣, 毛高平 . 足三里穴中频电刺激对健康人胃电活动的影响[J]. 中华理疗杂志, 2001,24(1):33
[11] Yang GX, Yang JZ, Wu DY . Diagnosis and treatment of functional delayed gastric emptying after subtotal gastrectomy[J]. Luzhou Yi Xue Yuan Xue Bao, 2007,30(3):195-197
doi: 10.3969/j.issn.1000-2669.2007.03.009
杨贵祥, 杨静兆, 吴大勇 . 胃大部切除术后残胃功能性排空障碍的诊断和治疗[J]. 泸州医学院学报, 2007,30(3):195-197
doi: 10.3969/j.issn.1000-2669.2007.03.009
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