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Journal of Chinese Integrative Medicine ›› 2003, Vol. 1 ›› Issue (1): 5-8.doi: 10.3736/jcim20030103

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Towards Integrative postmodern individualized medicine in terms of hierarchic emergence

Can Hou()   

  1. Zhongshan Medical College, Zhongshan University, Guangzhou, Guangdong Province 510089, China
  • Received:2003-03-11 Online:2003-03-20 Published:2018-10-19

The paper discusses the possibility and necessity for establishing a postmodern individualized medicine in terms of hierarchic emergence,a basic concept of contemporary system science. Through analysis of the strong and weak points of modern individualized medicine, personalized medicine and genomic medicine, the author found that Chinese traditional individualized medicine has its strong points in implementing whole (holistic) emergence and weak points in lower hierarchic emergence compared with the other three modern medical disciplines.Thus the author concluded that there are possibility and necessity to integrate the strong points of these medical systems for establishing a holistic and deepgoing patient-centered postmodern individualized medicine.

Key words: postmodern individualized medicine, Integrated TCM-WM, system theory

CLC Number: 

  • R2031
[1] 许国志 . 系统科学(第1版)[M]. 上海: 上海科技教育出版社, 2000,( 第1版):20-34
[2] Holland JH .Emergence--From chaos to order[M]. Oxford: Oxford Univ Pr, 1998: 1-9
[3] Williams RJ .Biochemical individuality--The basis for the genetotrophic concept[M]. New York: John Wiley & Sons, Inc, 1956: 195
[4] Hafter E . Gastroenterology yesterday and today[J]. Schweiz Med Wochenschr, 1976,106(9):262-266
[5] Miyachi H . Expanding scope and impact of services provided by clinical laboratory practice through molecular diagnostics[J]. Rinsho Byori, 1999,47(10):919-925
[6] Fischel-Ghodsian N . Mitochondrial DNA mutations and diabetes: another step toward individualized medicine[J]. Ann Intern Med, 2001,134(9):777-779
doi: 10.7326/0003-4819-134-9_Part_1-200105010-00014 pmid: 11329235
[7] Miyachi H . The present status and future prospect of the molecular diagnostic test[J]. Rinsho byori, 2001,49(2):139-149
pmid: 11307306
[8] Peltonen L, Mchusick VA . Dissecting human disease in postgenomic era[J]. Science, 2001,291(5507):1224-1229
doi: 10.1126/science.291.5507.1224
[9] Arnold RM, Forrow L . Rewarding medicine:good doctors and good behavior[J]. Ann Intern Med, 1990,113(10):794-798
doi: 10.1007/BF01798067 pmid: 2240883
[10] March R . Pharmacogenomics: the genomics of drug response[J]. Yeast, 2000,17(1):16-21
[11] Stephens JC . Single nucleotide polymorphisms, haplotypes, and their relevance to pharmacogenetics[J]. Mol Dign, 1999,4(4):309-317
doi: 10.154/MODI00400309 pmid: 10671641
[12] Bottles K . A revolution in genetics: changing medicine, changing lives[J]. Physician Exec, 2001,27(2):58-63
pmid: 11291222
[13] Yano K, Miki Y . Perspectives on postgenome medicine: Cancer[J]. Nippon Rinsho, 2001,59(1):31-37
pmid: 11197858
[14] Doyle DJ, Quackenbush J . Symposium on genomic medicine,University of Maryland[J]. Micro Comp Genomics, 1997,2(2):99-102
doi: 10.1089/omi.1.1997.2.99
[15] Beaudet AL . 1998 ASHG presidential address. Making genomic medicine a reality[J]. Am J Hum Genet, 1999,64(1):1-13
doi: 10.1086/302217
[16] Sander C . Genomic medicine and the future of health care[J]. Science, 2000,287(5460):1977-1978
doi: 10.1126/science.287.5460.1977 pmid: 10755952
[17] Collins FS, McKuisk VA . Implication of the Human Genome Project for medical science[J]. JAMA, 2001,285(5):540-544
doi: 10.1001/jama.285.5.540
[18] Coulter I . Genomic medicine: the sorcerer's new broom?The limitations of the human genome project[J]. West J Med, 2001,175(6):424-426
doi: 10.1136/ewjm.175.6.424
[19] 侯灿 . 后基因组时代的统一医药学——展望21世纪复杂性科学的一个新前沿(二)[J]. 中国中西医结合杂志, 2002,22(2):84-87
[20] Hartwell LH, Hopfield JJ, Leibler S , et al. From molecular to modular cell biology[J]. Nature, 1999,402(6761 Suppl):C47-C52
doi: 10.1038/35011540
[21] Gerstein M, Lan N, Jansen R . Integrating interactomes[J]. Science, 2002,295(5553):284-287
doi: 10.1126/science.1068664
[22] Hunter PJ, Borg TK . Integration from proteins to organs: The Physiome Project[J]. Nature Rev Molec Cell Biol, 2003,4(3):237-243
doi: 10.1016/j.mad.2004.09.025 pmid: 15610778
[23] Kitano H . Systems Biology: A brief overview[J]. Science, 2002,295(5560):1662-1664
doi: 10.1126/science.1069492 pmid: 11872829
[24] Noble D . Modeling the heart--from genes to cells to the whole organ[J]. Science, 2002,295(5560):1678-1682
doi: 10.1126/science.1069881
[25] Kiberstis P, Roberts L . It's not just the genes[J]. Science, 2002,296(5568):685
doi: 10.1126/science.296.5568.685
[26] Bianchi G, Muraglia A, Daga A , et al. Microenviroment and stem properties of bone marrow-derived mesenchymal cells[J]. Wound Repair Regen, 2001,9(6):460-466
doi: 10.1046/j.1524-475x.2001.00460.x pmid: 11896988
[27] Murdoch B, Gallacher L, Chadwick K , et al. Human embryonic-derived hematopoietic repopulating cells require distinct factors to sustain in vivo repopulating function[J]. Exp Hematol, 2002,30(6):598-605
doi: 10.1016/S0301-472X(02)00793-2
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