[an error occurred while processing this directive]

Journal of Chinese Integrative Medicine ›› 2005, Vol. 3 ›› Issue (3): 203-206.doi: 10.3736/jcim20050311

• Original Clinical Research • Previous Articles     Next Articles

Color Doppler ultrasound study on pathological changes of lower extremity arteries in patients with metabolic syndrome

Hao-qiang Yin,Xin Peng,Hu-sheng Xiao   

  1. Department of Function, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
  • Received:2005-04-01 Online:2005-05-20 Published:2005-05-20
  • Contact: Hu-sheng Xiao E-mail:xhsx@sina.com

RichHTML

2

PDF (PC)

64

Like

Objective

To explore the pathological changes of lower extremity arteries of patients with metabolic syndrome.

Methods

Fifty patients with metabolic syndrome (MS) and 30 normal volunteers were included in this study. The inner diameters, peak systolic velocities and intima-media thicknesses of the lower extremity arteries, and the sizes and numbers of the plaques in the lower extremity arteries were obtained with color Doppler ultrasound (CDU). 

Results

In the fifty MS patients, the intima-media thicknesses of forty-one were thicker than 1.1 mm and thirty-three had plaques which had brought stenosis in different degrees. The intima-media thicknesses of the common femoral, popliteal and posterior tibial arteries in the MS patients were significantly thicker than those in the normal volunteers (P<0.01 or P<0.05), and a greater number of plaques in the lower extremity arteries were observed in the patients, as compared with the normal volunteers (P<0.01).

Conclusion

Various pathological changes had taken place in the lower extremity arteries of the MS patients. The sites and degrees of the lower extremity arterial diseases in MS patients can be definitely detected with CDU.

Key words: Metabolic syndrome, Arteries, Lower extremity, Ultrasonography, Doppler, Color

CLC Number: 

  • R589

Tab 1

Ultrasonic characteristics of common femoral arteries in two groups ($\bar{x}$±s)"

Group n Diameter (mm) Vmax (cm/s) IMT (mm) Number of plaques
MS group
Left 50 7.64±1.07 87.01±3.12 1.27±0.05** 2.43±1.68**
Right 50 7.91±1.18 85.45±13.11 1.29±0.17** 2.55±1.10**
Control group
Left 30 8.10±1.23 82.35±9.41 0.73±0.07 0.23±0.50
Right 30 8.05±1.14 86.41±5.13 0.78±0.35 0.21±0.41

Tab 2

Ultrasonic characteristics of popliteal arteries in two groups ($\bar{x}$±s)"

Group n Diameter (mm) Vmax(cm/s) IMT (mm) Number of plaques
MS group
Left 50 5.14±0.11* 55.31±2.17 0.59±0.07** 2.32±1.55**
Right 50 5.23±0.22* 54.11±2.08 0.58±0.11* 2.51±1.14**
Control group
Left 30 5.53±0.31 55.13±3.25 0.41±0.05 0.28±0.47
Right 30 5.70±0.32 55.46±1.98 0.45±0.12 0.31±0.44

Tab 3

Ultrasonic characteristics of posterior tibial arteries in two groups ($\bar{x}$±s)"

Group n Diameter (mm) Vmax (cm/s) IMT (mm) Number of plaques
MS group
Left 50 1.33±0.28* 33.51±2.41** 0.53±0.21** 3.23±0.21**
Right 50 1.21±0.17* 31.40±3.11** 0.54±0.15** 3.15±0.17**
Control group
Left 30 1.93±0.25 45.50±3.29 0.34±0.17 0.38±0.14
Right 30 2.14±0.34 48.91±2.60 0.35±0.23 0.36±0.13
[1] 刘芳, 张红叶, 刘晓宁 , 等. 代谢综合征与动脉粥样硬化的关系[J]. 中华医学杂志, 2003,83(15):1317-1320
[2] 赵志钢, 祝之明, 李彦社 . 代谢综合征的颈动脉粥样硬化特征[J]. 中华内科杂志, 2003,42(9):625-627
[3] 李荆, 王贤金, 何小乔 . 多普勒频谱在下肢动脉疾病检查中的价值[J]. 中国超声诊断杂志, 2004,5(2):103-105
[4] 马文青, 纪东露, 孙勇 . 超声诊断在下肢动脉病变中的应用[J]. 中国超声诊断杂志, 2003,4(9):662-664
[5] 张琦, 赵宝珍, 翁三川 . 下肢动脉病变的二维彩色多普勒血流图检查[J]. 中国医学影像技术, 1999,15(11):854-855
[6] 齐春英, 崔广和 . 彩色多普勒超声在下肢动脉疾病诊断中的价值[J]. 中国超声医学杂志, 2001,17(7):549-551
doi: 10.3969/j.issn.1002-0101.2001.07.021
[7] 李建卫 .彩色多普勒超声对预防老年糖尿病下肢动脉病变的应用[J].海峡预防医学杂志, 2002, 8(4): 86, 89
doi: 10.3969/j.issn.1007-2705.2002.04.059
[8] 荆芜 . 代谢综合征及其诊断标准[J]. 辽宁实用糖尿病杂志, 2004,12(2):60
[9] Jia WP, Xiang KS, Chen L , et al. Epidemiological study on obesity and its comorbidities in urban Chinese older than 20 years of age in Shanghai, China[J]. Obes Rev, 2002,3(3):157-165
doi: 10.1046/j.1467-789X.2002.00071.x
[10] Ford ES, Giles WH, Dietz WH . Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey[J]. JAMA, 2002,287(3):356-359
doi: 10.1001/jama.287.3.356
[11] Resnick HE , Strong Heart Study Investigators.Metabolic syndrome in American Indians[J]. Diabetes Care, 2002,25(7):1246-1247
doi: 10.2337/diacare.25.7.1246 pmid: 12087031
[12] DeFronzo RA, Ferrannini E . Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease[J]. Diabetes Care, 1991,14(3):173-194
[1] Gerhard Litscher. High-tech acupuncture made in Austria — cerebral circulation. Journal of Chinese Integrative Medicine, 2012, 10(4): 362-368.
[2] Hsin Hsiu, Wei-Chen Hsu, Shih-Ming Huang, Chia-Ching Lin, Hung-Wen Lin. Assessing the microcirculatory response following oral administration of Liuwei Dihuang formula by spectral analysis of skin-surface laser Doppler signals. Journal of Chinese Integrative Medicine, 2011, 9(10): 1101-1109.
[3] Yi Chen, Wen-jian Wang. Relationships between insulin resistant and hypertension and traditional Chinese medicine intervention. Journal of Chinese Integrative Medicine, 2010, 8(12): 1114-1118.
[4] Xian-jun Tong, Xiao-yu Xiang, Zun-hua Cheng, Li Chen, Xian-chuan Chen, Jing-xian Chen. Color Doppler ultrasound evaluation of a Chinese herbal formula in treating lower limb arteriosclerosis: A randomized controlled trial. Journal of Chinese Integrative Medicine, 2009, 7(6): 518-521.
[5] Xin Peng , Hao-qiang Yin, Rong-juan Xu, Hu-sheng Xiao. Correlative analysis of the parameters of eTRACKING detection of femoral artery and the syndrome types of traditional Chinese medicine in type 2 diabetic patients. Journal of Chinese Integrative Medicine, 2009, 7(10): 929-933.
[6] Lian-qing Sun, Yan Yang, Wei Zheng. Relationship between syndrome differentiation of traditional Chinese medicine and vascular endothelial function in patients with diabetic arterial occlusion of lower extremities. Journal of Chinese Integrative Medicine, 2007, 5(6): 621-624.
[7] Chun-yan He, Wen-jian Wang, Bin Li, De-sheng Xu, Wei-hua Chen, Jiang Ying, Yan-ming He. Clinical research of Yiqi Sanju Formula in treating central obese men at high risk of metabolic syndrome. Journal of Chinese Integrative Medicine, 2007, 5(3): 263-267.
[8] Wen-jian Wang. Foundation and application of aggregation syndrome theory in traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2007, 5(2): 111-114.
[9] Wen-jian Wang. Prevention and treatment of metabolic syndrome with integrated traditional Chinese and Western medicine. Journal of Chinese Integrative Medicine, 2004, 2(5): 390-395.
[10] Zheng He, Yue Wu, Mei-xian Jiang, Rong-qi Cheng, Rui Shen. Observation by color Doppler ultrasound on endothelium-dependent dilation of congestive heart failure treated with Kanli Decoction. Journal of Chinese Integrative Medicine, 2004, 2(5): 268-270.
[11] Xu-min Hou, Huan-chun Ni, Xin-ping Luo, Hai-ming Shi, Wei-hu Fan. Effect of Zhenju Jiangya Tablet on the endothelial function of hyperlipidemic rabbits. Journal of Chinese Integrative Medicine, 2004, 2(2): 111-114.
[12] Cun-jun Zhang, Song-po Wang, Hong Yang, Jie Chi, Yong Jiang, Zheng-ming Jiang. A study on relationship of purple tongue and its regional blood flow. Journal of Chinese Integrative Medicine, 2004, 2(1): 27-29.
[13] Li Chen, Hong-sheng Zhan. An transcranial Doppler ultrasonography and X-ray study of cervical vertigo patients treated by manipulation in supine position. Journal of Chinese Integrative Medicine, 2003, 1(4): 262-264.
Viewed
Full text


Abstract

Cited
  Shared   
  Discussed   
[1] Jin-zhou Tian, Jing Shi, Xin-qing Zhang, Qi Bi, Xin Ma, Zhi-liang Wang, Xiao-bin Li, Shu-li Shen, Lin Li, Zhen-yun Wu, Li-yan Fang, Xiao-dong Zhao, Ying-chun Miao, Peng-wen Wang, Ying Ren, Jun-xiang Yin, Yong-yan Wang, Beijing United Study Group on MCI of the Capital Foundation of Medical Developments. An explanation on "guiding principles of clinical research on mild cognitive impairment (protocol)". Journal of Chinese Integrative Medicine, 2008, 6(1): 15-21
[2] Yi-ting He, Qing-lin Zha, Jian-ping Yu, Yong Tan, Cheng Lu, Ai-ping Lv. Principal factor analysis of symptoms of rheumatoid arthritis and their correlations with efficacy of traditional Chinese medicine and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 32-36
[3] Jun Cai, Hua Wang, Sheng Zhou, Bin Wu, Hua-rong Song, Zheng-rong Xuan. Effect of Sijunzi Decoction and enteral nutrition on T-cell subsets and nutritional status in patients with gastric cancer after operation: A randomized controlled trial. Journal of Chinese Integrative Medicine, 2008, 6(1): 37-40
[4] Wei Zhang, Xiang-feng Lu, Xiao-mei Zhang, Jian-jun Wu, Liang-duo Jiang. A rat model of pulmonary fibrosis induced by infusing bleomycin quickly through tracheal intubation. Journal of Chinese Integrative Medicine, 2008, 6(1): 60-67
[5] A-gao Zhou, Yong Zhang, Gang Kui, De-Yun Kong, Hai-liang Ge, Qiu-hua Ren, Jia-rong Dong, Sheng Hong, Xu-ming Mao, Yin Wang, Hui-zheng Zhang, Shu-jun Wang. Influence of traditional Chinese compound recipes with different efficacy on body weight, tumor weight and immune function in H22 cancer-bearing mice. Journal of Chinese Integrative Medicine, 2008, 6(1): 77-82
[6] Guo-hong Yuan, Xiao-jing Pang, He-chao Ma. Synergic effects of Danggui Buxue Decoction in reducing toxicity of cytoxan in tumor-bearing mice. Journal of Chinese Integrative Medicine, 2008, 6(1): 83-88
[7] Li Zhou, Hong-xing Zhang, Ling-guang Liu, Wen-jun Wan. Effect of electro-acupuncture at Fenglong (GV 16) on nitric oxide and endothelin in rats with hyperlipidemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 89-92
[8] Jin-zhou Tian, Jing Shi, Xin-qing Zhang, Qi Bi, Xin Ma, Zhi-liang Wang, Xiao-bin Li, Shu-li Shen, Lin Li, Zhen-yun Wu, Li-yan Fang, Xiao-dong Zhao, Ying-chun Miao, Peng-wen Wang, Ying Ren, Jun-xiang Yin, Yong-yan Wang, Beijing United Study Group on MCI of the Capital Foundation of Medical Developments. Guiding principles of clinical research on mild cognitive impairment (protocol). Journal of Chinese Integrative Medicine, 2008, 6(1): 9-14
[9] Xin-jun Wang, Ling-ling Wang . A mechanism of endogenous opioid peptides for rapid onset of acupuncture effect in treatment of depression. Journal of Chinese Integrative Medicine, 2010, 8(11): 1014-1017
[10] Bo Wang , Wei Yan , Li-hui Hou, Xiao-ke Wu. Disorder of Tiangui (kidney essence) and reproductive dysfunction in patients with polycystic ovary syndrome. Journal of Chinese Integrative Medicine, 2010, 8(11): 1018-1022
[an error occurred while processing this directive]