健脾补肾中药联合氯沙坦治疗慢性肾功能不全

doi:10.3736/jcim20060423

Abstract

CLC Number:

R563.9

Wei Deng, Hao-gu Ding, Jing Chen. Treatment of chronic renal insufficiency with losartan and traditional Chinese drug for invigorating spleen and kidney. Journal of Chinese Integrative Medicine, 2006, 4(4): 425-426.

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[1]	崔彤霞, 汪涛 . 血管紧张素转化酶抑制剂和血管紧张素Ⅱ受体拮抗剂在肾脏病的应用[J]. 中国中西医结合肾病杂志, 2000,1(1):62-64 doi: 10.3969/j.issn.1009-587X.2000.01.026
[2]	王丽 . AT-Ⅱ受体及其拮抗剂对人肾功能的保护作用[J]. 国外医学·泌尿系统分册, 1997,17(3):106-107

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组别	n	sCr（mmol/L）	BUN（mmol/L）	UA（mmol/L）	24h尿蛋白定量（g）
中药加氯沙坦组
治疗前	45	237.90±70.02	13.10±5.40	510.20±90.40	1.90±0.92
治疗后	45	166.12±36.40**	7.40±3.60**	312.60±83.20**	1.03±0.18**
氯沙坦组
治疗前	41	238.70±66.75	12.45±5.21	535.30± 84.10	1.92±0.94
治疗后	41	173.20±35.25**	8.50±2.30**	389.80±80.40**	1.37±0.29*
硝苯地平组
治疗前	44	236.90±72.20	13.28±5.90	518.50±80.60	1.91±0.91
治疗后	44	214.50±55.60	10.90±3.00	511.70±78.50	1.76±0.32

组别	n	收缩压	舒张压
中药加氯沙坦组
治疗前	45	167.5±11.1	101.1±7.8
治疗2周后	45	148.4±10.2	94.2±6.8
治疗4周后	45	138.9±10.5*	89.2±6.5*
治疗8周后	45	128.0±9.7**	82.0±4.1**
氯沙坦组
治疗前	41	168.2±12.1	101.2±7.8
治疗2周后	41	150.7±12.2	94.2±6.5
治疗4周后	41	141.3±9.2*	88.6±6.4*
治疗8周后	41	128.8±12.4**	82.2±4.4**
硝苯地平组
治疗前	44	167.1±9.7	99.8±7.1
治疗2周后	44	152.4±8.7	94.0±6.3
治疗4周后	44	140.0±11.5*	94.2±4.6
治疗8周后	44	138.2±11.4*	89.4±6.0*

Treatment of chronic renal insufficiency with losartan and traditional Chinese drug for invigorating spleen and kidney

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