Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2007, Vol. 5 ›› Issue (6): 707-711.doi: 10.3736/jcim20070622

• Medical Statistics • Previous Articles     Next Articles

Discrimination and interpretation of errors of experimental designs in medical papers

Liang-ping Hu1, Hui-gang Liu2   

  1. 1. Consulting Center of Biomedical Statistics,Academy of Military Medical Sciences,Beijing 100850,China
    2. College of Basic Medical Sciences,Capital University of Medical Sciences,Beijing 100069,China
  • Online:2007-11-20 Published:2007-11-15

Key words: medicine, dissertation, statistical analysis, experimental design

CLC Number: 

  • O212


组别 例数 TNF-α (μg/L) MPO (U/g)
假手术组 6 0.601±0.089 0.026±0.008
模型组 6 1.576±0.153** 0.409±0.044**
川芎嗪组 6 1.035±0.092**△△ 0.293±0.039**△△


是否制备局灶性脑缺血再灌注模型 例数 TNF-α (μg/L) MPO (U/g)
6 1.035±0.092 1.576±0.153 0.293±0.039 0.409±0.044
6 ? 0.601±0.089 ? 0.026±0.008


组别 例数 时间 hsCRP (mg/L) IL-6 (ng/L) TNF-α (ng/L) WBC (×109/L)
非CAD组 20 1.13±0.73 2.87±1.45 5.84±1.96 5.37±1.30
对照组 20 治疗前 2.74±1.07 7.33±2.15 12.10±4.14 7.58±3.01
治疗后 2.45±0.96 6.80±1.58 10.28±5.74 7.04±3.20
用药组 20 治疗前 2.68±0.94 7.04±2.10 12.35±5.36 7.60±2.92
治疗后 1.85±0.66 5.71±1.01 7.72±3.10 5.86±1.42


组别 例数 时间 hsCRP (mg/L) IL-6 (ng/L) TNF-α (ng/L) WBC (×109/L)
非CAD组 20 1.13±0.73 2.87±1.45 5.84±1.96 5.37±1.30
CAD组 40 治疗前 ? ? ? ?


组别 例数 时间 hsCRP (mg/L) IL-6 (ng/L) TNF-α (ng/L) WBC (×109/L)
对照组 20 治疗前 2.74±1.07 7.33±2.15 12.10±4.14 7.58±3.01
治疗后 2.45±0.96 6.80±1.58 10.28±5.74 7.04±3.20
治疗组 20 治疗前 2.68±0.94 7.04±2.10 12.35±5.36 7.60±2.92
治疗后 1.85±0.66 5.71±1.01 7.72±3.10 5.86±1.42
[1] 胡良平 . 医学统计实用手册[M]. 北京: 人民卫生出版社, 2004: 1-76
Hu LP. Practical handbook of medical statistics[M]. Beijing: People's Medical Publishing House, 2004: 1-76
[2] 胡良平, 李子建 . 医学统计学基础与典型错误辨析[M]. 北京: 军事医学科学出版社, 2003: 242-259
Hu LP, Li ZJ. Fundamental of medical statistics and discrimination of typical misuse[M]. Beijing: Press of Military, 2003: 242-259
[3] 胡良平 . 统计学三型理论在实验设计中的应用[M]. 北京: 人民军医出版社, 2006: 139-165
Hu LP . Application of triple-type theory of statistics in[M]. Beijing: People' s Military Medical, 2006: 139-165
[1] Tara Rajendran. Addressing the need for personalizing music therapy in integrative oncology. Journal of Integrative Medicine, 2022, 20(4): 281-283.
[2] Wan-jun Guo, Yi Wang, Yu Deng, Lin-yan Cheng, Xin Liu, Ruo-fan Xi, Sheng-jie Zhu, Xin-yi Feng, Liang Hua, Kan Ze, Jian-yong Zhu, Dong-jie Guo, Fu-lun Li. Therapeutic effects of the extract of Sancao Formula, a Chinese herbal compound, on imiquimod-induced psoriasis via cysteine-rich protein 61. Journal of Integrative Medicine, 2022, 20(4): 376-384.
[3] Cai-lian Fana, Wan-jun Caib, Meng-nan Ye, Miao Chen, Yi Dai. Qili Qiangxin, a compound herbal medicine formula, alleviates hypoxia-reoxygenation-induced apoptotic and autophagic cell death via suppression of ROS/AMPK/mTOR pathway in vitro. Journal of Integrative Medicine, 2022, 20(4): 365-375.
[4] Shang-jin Song, Xuan Liu, Qing Ji, Da-zhi Sun, Li-juan Xiu, Jing-yu Xu, Xiao-qiang Yue. Ziyin Huatan Recipe, a Chinese herbal compound, inhibits migration and invasion of gastric cancer by upregulating RUNX3 expression. Journal of Integrative Medicine, 2022, 20(4): 355-364.
[5] Vibha Malhotra, Joanna Harnett, Erica McIntyre, Amie Steel, Keith Wong, Bandana Saini. To “tell or not to tell”—Exploring disclosure about medicine use by people living with sleep disorders. Journal of Integrative Medicine, 2022, 20(4): 338-347.
[6] Maryam Azimi, Hanieh Niayesh, Mahboobeh Raeiszadeh, Sedigheh Khodabandeh-shahraki. Efficacy of the herbal formula of Foeniculum vulgare and Rosa damascena on elderly patients with functional constipation: A double-blind randomized controlled tria. Journal of Integrative Medicine, 2022, 20(3): 230-236.
[7] Marisa Casal. Improving the health and treatment success rates of in vitro fertilization patients with traditional chinese medicine: need for more robust evidence and innovative approaches. Journal of Integrative Medicine, 2022, 20(3): 187-192.
[8] Ning Guo, Fei Wu, Mei Wu, Yuan Wang, Qing Lang, Xiao Lin, Yi Feng. Progress in the design and quality control of placeboes for clinical trials of traditional Chinese medicine . Journal of Integrative Medicine, 2022, 20(3): 204-212.
[9] Tareq A. Wani, Zahoor A. Kaloo, Nisar A. Dangroo. Aconitum heterophyllum Wall. ex Royle: A critically endangered medicinal herb with rich potential for use in medicine. Journal of Integrative Medicine, 2022, 20(2): 104-113.
[10] Mohammad Fazil, Sadia Nikhat. Why the “sugars” in traditional Unani formulations are a pivotal component: A viewpoint perspective. Journal of Integrative Medicine, 2022, 20(2): 91-95.
[11] Yan-jun Lin, Kun-li Jiao, Bo Liu, Lu Fang, Shu Meng. Antiplatelet and myocardial protective effect of shexiang tongxin dropping pill in patients undergoing percutaneous coronary intervention: A randomized controlled trial. Journal of Integrative Medicine, 2022, 20(2): 126-134.
[12] Deng-chao Wang, Miao Yu, Wen-xian Xie, Li-yan Huang, Jian Wei, Yue-hua Lei. Meta-analysis on the effect of combining Lianhua Qingwen with Western medicine to treat coronavirus disease 2019. Journal of Integrative Medicine, 2022, 20(1): 26-33.
[13] Mahlagha Dehghan, Alireza Ghanbari, Fatemeh Ghaedi Heidari, Parvin Mangalian, Mohammad Ali Zakerid. Use of complementary and alternative medicine in general population during COVID-19 outbreak: A survey in Iran. Journal of Integrative Medicine, 2022, 20(1): 45-51.
[14] Jose Antonio Castilla-Jimena, Isabel Ruiz-Pérez, Jesús Henares-Montiel. Impact of socioeconomic and health-related factors on consumption of homeopathic and natural remedies in Spain in 2006, 2011 and 2017. Journal of Integrative Medicine, 2022, 20(1): 52-56.
[15] Ofer Baranovitch, Meirav Wolff-Bar, Meora Feinmesser, Chen Sade-Zaltz, Ilan Tsarfaty, Victoria Neiman. Searching for the emotional roots of breast cancer: A cross-disciplinary analysis integrating psychology, Chinese medicine, and oncology biomarkers. Journal of Integrative Medicine, 2022, 20(1): 57-64.
Full text



[1] Dong Yang, Yong-ping Du, Qing Shen, Wei Chen, Yan Yu, Guang-lei Chen. Expression of alpha-smooth muscle actin in renal tubulointerstitium in patients with kidney collateral stasis. Journal of Chinese Integrative Medicine, 2008, 6(1): 41-44
[2] Hai-feng Wei, Bai-liu Ya, Ling Zhao, Cui-fei Ye, Li Zhang, Lin Li. Evaluation of tongue manifestation of blood stasis syndrome and its relationship with blood rheological disorder in a rat model of transient brain ischemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 73-76
[3] Xi Lin, Jian-ping Liu. Herbal medicines for viral myocarditis. Journal of Chinese Integrative Medicine, 2008, 6(1): 76
[4] Xi Lin, Jian-ping Liu. Tai chi for treating rheumatoid arthritis. Journal of Chinese Integrative Medicine, 2008, 6(1): 82
[5] Liang-ping Hu, Hui Gao. Discrimination of errors in statistical analysis of medical papers published in the first issue of 2006 in Journal of Chinese Integrative Medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 98-106
[6] Yan-bo Zhu , Qi Wang, Cheng-yu Wu, Guo-ming Pang, Jian-xiong Zhao, Shi-lin Shen, Zhong-yuan Xia , Xue Yan . Logistic regression analysis on relationships between traditional Chinese medicine constitutional types and overweight or obesity. Journal of Chinese Integrative Medicine, 2010, 8(11): 1023-1035
[7] Wei Xu, Meng Shi, Jian-gang Liu, Cheng-long Wang . Collagen protein expressions in ischemic myocardium of rats with acute myocardial infarction and effects of qi-tonifying, yin-tonifying and blood-activating herbs and detoxifying and blood-activating herbs. Journal of Chinese Integrative Medicine, 2010, 8(11): 1041-1047
[8] Tao Wang , Feng Qin. Effects of Chinese herbal medicine Xiaoyao Powder on monoamine neurotransmitters in hippocampus of rats with postpartum depression. Journal of Chinese Integrative Medicine, 2010, 8(11): 1075-1079
[9] Ying Xu , Chang-chun Zeng , Xiu-yu Cai , Rong-ping Guo , Guang Nie , Ying Jin. Chromaticity and optical spectrum colorimetry of the tongue color in different syndromes of primary hepatic carcinoma. Journal of Chinese Integrative Medicine, 2012, 10(11): 1263-1271
[10] Xiang-ying Mao , Qin Bian , Zi-yin Shen. Analysis of the osteogenetic effects exerted on mesenchymal stem cell strain C3H10T1/2 by icariin via MAPK signaling pathway in vitro. Journal of Chinese Integrative Medicine, 2012, 10(11): 1272-1278