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Journal of Chinese Integrative Medicine ›› 2013, Vol. 11 ›› Issue (3): 168-174.doi: 10.3736/jintegrmed2013030

Special Issue: Acupuncture & Moxibustion

• Research Article • Previous Articles     Next Articles

Introduction of two novel devices for investigating the influence of non-mechanical components such as therapeutic qi in acupuncture

Raphael J. Hochstrassera,bP. Christian Endlera, Klein D. Sabinec,d()   

  1. a. Interuniversity College for Health and Development Graz, Castle of Seggau, 8042 Graz, Austria
    b. TCM Practice Aarau, Ochsengässli 7, 5000 Aarau, Switzerland
    c. Institute of Complementary Medicine KIKOM, University of Bern, 3010 Bern, Switzerland
    d. Research Working Group, Swiss Professional Organization for Traditional Chinese Medicine SBO-TCM, 9113 Degersheim, Switzerland
  • Received:2013-02-13 Accepted:2013-03-26 Online:2013-05-10 Published:2013-05-15

Objective

Acupuncture is a complex intervention consisting of specific and non-specific components. Acupuncture studies more frequently focus on collecting data from the patients’ perspective and response, but the acupuncturist’s role remains relatively unclear. In order to investigate potential non-mechanical active factors originating from the acupuncturist and transmitted to the patient during treatment, two novel devices for basic research in acupuncture were designed. The Acuplicator allows the researcher to insert needles without touching the needles themselves, while the Veliusator locks the needle in its place so that no mechanical movement can be transferred.


Methods

The Acuplicator was used to insert needles at Neiguan (PC6) on the right forearm of 23 volunteers. The insertion depth was measured using a depth gauge. The transfer of mechanical movements from the handle to the tip was detected with a precision length gauge with a motoric-tactile sensor.


Results

The mean insertion depth was (12.3 ± 1.5) mm (range 9.5 to 15.0 mm). Even with intense manipulation of the needle handle, no movements within ± 1 μm could be detected at the tip when the needle was locked.


Conclusion

With these two devices it will be possible to investigate the influence of non-mechanical components such as therapeutic qi in acupuncture.

Key words: Acupuncture, Needling sensation response, Acupuncture sensation

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Figure 1

Construction plan of the AcuplicatorNumbers represent distances in mm. A, B and C are corresponding sections on the different views of the device."

Figure 2

Construction plan of the VeliusatorNumbers represent distances in mm. A, B and C are corresponding sections on the different views of the device."

Figure 3

Acuplicator in use."

Figure 4

Veliusator in use(a) With open slides. (b) With locked slides. The wooden boards above the volunteer’s hand serve as insulation, so that the volunteer does not feel the warmth of the acupuncturist’s hand."

[1] Hao XA, Xue CC, Dong L, Zheng Z. Factors associated with conflicting findings on acupuncture for tension-type headache: qualitative and quantitative analyses. J Altern Complement Med. 2012 Oct 17. [Epub ahead of print]
[2] Sun S, Dai J, Wang W, Cao H, Fang J, Hu YY, Su S, Zhang Y . Metabonomic evaluation of ZHENG differentiation and treatment by Fuzhenghuayu Tablet in hepatitis-B-caused cirrhosis[J]. Evid Based Complement Alternat Med, 2012,2012:453503
[3] Wei H, Pasman W, Rubingh C, Wopereis S, Tienstra M, Schroen J, Wang M , Verheij E, van der Greef J.Urine metabolomics combined with the personalized diagnosis guided by Chinese medicine reveals subtypes of pre-diabetes[J]. Mol Biosyst, 2012,8(5):1482-1491
doi: 10.1039/c2mb05445k
[4] Ahn AC, Colbert AP, Anderson BJ, Martinsen OG, Hammerschlag R, Cina S, Wayne PM, Langevin HM . Lectrical properties of acupuncture points and meridians: a systematic review[J]. Bioelectromagnetics, 2008,29(4):245-256
doi: 10.1002/(ISSN)1521-186X
[5] Ahn AC, Park M, Shaw JR , McManus CA, Kaptchuk TJ, Langevin HM.Electrical impedance of acupuncture meridians: the relevance of subcutaneous collagenous bands[J]. PLoS One, 2010,5(7):e11907
doi: 10.1371/journal.pone.0011907
[6] Li Y, Zheng H, Witt CM, Roll S, Yu SG, Yan J, Sun GJ, Zhao L, Huang WJ, Chang XR, Zhang HX, Wang DJ, Lan L, Zou R, Liang FR . Acupuncture for migraine prophylaxis: a randomized controlled trial[J]. CMAJ, 2012,184(4):401-410
doi: 10.1503/cmaj.110551
[7] Langevin HM, Yandow JA . Relationship of acupuncture points and meridians to connective tissue planes[J]. Anat Rec, 2002,269(6):257-265
doi: 10.1002/(ISSN)1097-0185
[8] Streitberger K, Kleinhenz J . Introducing a placebo needle into acupuncture research[J]. Lancet, 1998,352(9125):364-365
doi: 10.1016/S0140-6736(97)10471-8
[9] Lee S, Lim N, Choi SM, Kim S . Validation study of Kim’s sham needle by measuring facial temperature: An N-of-1 randomized double-blind placebo-controlled clinical trial[J]. Evid Based Complement Alternat Med, 2012,2012:507937
[10] Langevin HM, Churchill DL, Cipolla MJ . Mechanical signaling through connective tissue: a mechanism for the therapeutic effect of acupuncture[J]. FASEB J, 2001,15(12):2275-2282
doi: 10.1096/fj.01-0015hyp
[11] Langevin HM, Churchill DL, Fox JR, Badger GJ, Garra BS, Krag MH . Biomechanical response to acupuncture needling in humans[J]. J Appl Physiol, 2001,91(6):2471-2478
doi: 10.1152/jappl.2001.91.6.2471
[12] Davis RT, Churchill DL, Badger GJ, Dunn J, Langevin HM . A new method for quantifying the needling component of acupuncture treatments[J]. Acupunct Med, 2012,30(2):113-119
doi: 10.1136/acupmed-2011-010111
[13] Kong J, Gollub R, Huang T, Polich G, Napadow V, Hui K, Vangel M, Rosen B, Kaptchuk TJ . Acupuncture de qi, from qualitative history to quantitative measurement[J]. J Altern Complement Med, 2007,13(10):1059-1070
doi: 10.1089/acm.2007.0524
[14] Shi GX, Yang XM, Liu CZ, Wang LP . Factors contributing to therapeutic effects evaluated in acupuncture clinical trials[J]. Trials, 2012,13:42
doi: 10.1186/1745-6215-13-42
[15] Xiong J, Liu F, Zhang MM, Wang W, Huang GY . De-qi, not psychological factors, determines the therapeutic efficacy of acupuncture treatment for primary dysmenorrhea[J]. Chin J Integr Med, 2012,18(1):7-15
doi: 10.1007/s11655-011-0857-1
[16] Asghar AU, Green G, Lythgoe MF, Lewith G , MacPherson H.Acupuncture needling sensation: the neural correlates of deqi using fMRI[J]. Brain Res, 2010,1315:111-118
doi: 10.1016/j.brainres.2009.12.019
[17] Ceccherelli F, Gioioso L, Casale R, Gagliardi G, Ori C . Neck pain treatment with acupuncture: does the number of needles matter? Clin[J] Pain. 2010; 26(9):807-812.
[18] White P, Bishop FL, Prescott P, Scott C, Little P, Lewith G . Practice, practitioner, or placebo? A multifactorial, mixed-methods randomized controlled trial of acupuncture[J]. Pain, 2012,153(2):455-462
[19] Colagiuri B, Smith CA . A systematic review of the effect of expectancy on treatment responses to acupuncture[J]. Evid Based Complement Alternat Med, 2012,2012:857804
[20] Witt CM, Martins F, Willich SN, Schützler L . Can I help you? Physicians’ expectations as predictor for treatment outcome[J]. Eur J Pain, 2012,16(10):1455-1466
doi: 10.1002/ejp.2012.16.issue-10
[21] Greenwood MT . Acupuncture and intention: needling without needles[J]. Med Acupunct, 1999,11(1):17-24
[22] MacPherson H, Thorpe L, Thomas K . Beyond needling - therapeutic process in acupuncture care: a qualitative study nested within a low-back pain trial[J]. J Altern Complement Med, 2006,12(9):873-880
doi: 10.1089/acm.2006.12.873
[23] Liu T . Role of acupuncturists in acupuncture treatment[J]. Evid Based Complement Alternat Med, 2007,4(1):3-6
[24] Street RL Jr, Cox V, Kallen MA, Suarez-Almazor ME . Exploring communication pathways to better health: Clinician communication of expectations for acupuncture effectiveness[J]. Patient Educ Couns, 2012,89(2):245-251
doi: 10.1016/j.pec.2012.06.032
[25] Chung VC, Ma PH, Lau CH, Wong SY, Yeoh EK, Griffiths SM . Views on traditional Chinese medicine amongst Chinese population: a systematic review of qualitative and quantitative studies. Health Expect. 2012 May 31. [Epub ahead of print]
[26] Kamper SJ, Williams CM . The placebo effect: powerful, powerless or redundant? Br[J] Sports Med. 2013; 47(1):6-9.
[27] Moerman DE . Meaningful placebos - controlling the uncontrollable[J]. N Engl J Med, 2011,365(2):171-172
doi: 10.1056/NEJMe1104010
[28] Takakura N, Yajima H . A double-blind placebo needle for acupuncture research[J]. BMC Complement Altern Med, 2007,7:31
doi: 10.1186/1472-6882-7-31
[29] Haake M, Müller HH, Schade-Brittinger C, Basler HD , Schfer H, Maier C, Endres HG, Trampisch HJ, Molsberger A.German Acupuncture Trials(GERAC) for chronic low back pain: randomized, multicenter, blinded, parallel-group trial with 3 groups[J]. Arch Intern Med, 2007,167(17):1892-1898
doi: 10.1001/Archinte.167.17.1892
[30] Vickers AJ, Cronin AM, Maschino AC, Lewith G , MacPherson H, Foster NE, Sherman KJ, Witt CM, Linde K; Acupuncture Trialists’ Collaboration.Acupuncture for chronic pain: Individual patient data meta-analysis[J]. Arch Intern Med, 2012,172(19):1444-1453
doi: 10.1001/archinternmed.2012.3654
[31] Ezzo J, Vickers A, Richardson MA, Allen C, Dibble SL, Issell B, Lao L, Pearl M, Ramirez G, Roscoe JA, Shen J, Shivnan J, Streitberger K, Treish I, Zhang G . Acupuncture-point stimulation for chemotherapy-induced nausea and vomiting[J]. J Clin Oncol, 2005,23(28):7188-7198
doi: 10.1200/JCO.2005.06.028
[32] Streitberger K, Eichenberger U, Schneider A, Witte S, Greher M . Ultrasound measurements of the distance between acupuncture needle tip at P6 and the median nerve[J]. J Altern Complement Med, 2007,13(5):585-591
doi: 10.1089/acm.2007.6247
[33] Park J, White A, Stevinson C, Ernst E, James M . Validating a new non-penetrating sham acupuncture device: two randomised controlled trials[J]. Acupunct Med, 2002,20(4):168-174
doi: 10.1136/aim.20.4.168
[34] Takakura N, Takayama M, Kawase A, Kaptchuk TJ, Yajima H . Double blinding with a new placebo needle: a further validation study[J]. Acupunct Med, 2010,28(3):144-148
doi: 10.1136/aim.2009.001230
[35] Takakura N, Takayama M, Kawase A, Yajima H . Double blinding with a new placebo needle: a validation study on participant blinding[J]. Acupunct Med, 2011,29(3):203-207
doi: 10.1136/aim.2010.002857
[36] Takakura N, Takayama M, Kawase A, Yajima H. Tapping-in method (skin penetration technique) with a placebo needle for double-blind acupuncture trials. J Altern Complement Med. 2012 Oct 25. [Epub ahead of print]
[37] Anderson B, Nielsen A , McKee D, Jeffres A, Kligler B.Acupuncture and heart rate variability: a systems level approach to understanding mechanism[J]. Explore (NY), 2012,8(2):99-106
doi: 10.1016/j.explore.2011.12.002
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