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Journal of Chinese Integrative Medicine ›› 2009, Vol. 7 ›› Issue (12): 1130-1133.doi: 10.3736/jcim20091207

• Original Clinical Research • Previous Articles     Next Articles

Kneading and dispersing manipulation in treatment of early-stage acute mastitis: A randomized controlled trial

Min Zhoua,Xin Lia,Yi-qin Chengb,Rong Shenc, Ying Zhaoa,Huai-zhi Zhaoa,Juan Wanga,Dong-mei Shia   

  1. a Department of Chinese Traditional Surgery, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China
    b Department of Chinese Traditional Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    c Department of Maternity, Shanghai Yangpu Maternity and Child Health Hospital, Shanghai 200082, China
  • Received:2009-09-09 Accepted:2009-11-12 Online:2009-12-20 Published:2009-12-15
  • Contact: Min Zhou


Acute mastitis is an acute infectious disease of breast. Antibiotic treatment is often unable to obtain a good effect, and we should actively look for a safe and effective non-drug therapy.

To validate the clinical efficacy of kneading and dispersing manipulation in treatment of early-stage acute mastitis.Design, setting, participants and interventions: According to the multicenter randomized controlled trial design, 198 cases of acute mastitis from Yueyang Hospital of Integrated Traditional Chinese Medicine, Longhua Hospital, and Shanghai Yangpu Maternity and Child Health Hospital were randomly divided into treatment group and control group. There were 99 cases in each group. Patients in the treatment group were only treated with manipulation, and cefradine was orally administered to patients in the control group.Main outcome measures: The local breast lump size, clinical symptoms and the adverse reactions in the two groups were observed before and after the treatment.

The total response rates in the treatment and control group were 95.92% (94/98) and 80% (76/95) respectively. There was a significant difference in the total response rate between the two groups (P<0.05). There were significant differences in the score of breast lump size, and the score of signs and symptoms between the two groups (P<0.05).

Kneading and dispersing manipulation has certain effects on early-stage acute mastitis, and the therapy is safe and repeatable.

Key words: Acute mastitis, Kneading and dispersing manipulation, Treatment effectiveness, Multicenter studies, Randomized control trial

Figure 1

Flow diagram of this randomized trial"

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