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Journal of Chinese Integrative Medicine ›› 2010, Vol. 8 ›› Issue (6): 510-524.doi: 10.3736/jcim20100602

• Review • Previous Articles     Next Articles

Comprehensive review of Clerodendrum phlomidis: A traditionally used bitter

Muthu Kumaradoss MOHAN MARUGA RAJA,Shri Hari MISHRA   

  1. Herbal Drug Technology Laboratory, Pharmacy Department, The Maharaja Sayajirao University of Baroda, Vadodara-390002, Gujarat, India
  • Received:2010-03-12 Accepted:2010-04-28 Online:2010-06-20 Published:2010-06-15

Clerodendrum phlomidis Linn. f., (syn. Clerodendrum multiflorum (Burm.f) O. Kuntze, Volkameria multiflorum Burm. f.) (Lamiaceae) is an important and well known medicinal plant extensively used in Ayurveda and Siddha system of medicine for treatment of various ailments. The popular therapies include on inflammation, diabetes, nervous disorder, asthma, rheumatism, digestive disorders, and urinary disorders as well as a bitter tonic. It was reported that pectolinaringenin, scutellarein, clerodin, clerodendrin, clerosterol, 24β-ethylcholesta-5,22E,25-triene-3β-ol, lup-20(29)-en-3-triacontanoate, 4,2′,4′-trihydroxy-6′-methoxychalcone-4,4′α-D-diglucoside, 7-hydroxyflavone, 7-hydroxyflavanone-7-O-glucoside and α-L-rhamnopyranosyl-(1→2)α-D-glucopyranosyl-7-O-naringin-4′-O-α-D-glucopyranoside-5-methyl ether had been isolated from this plant. The alcoholic and aqueous extracts were reported active as analgesic, antidiarrhoeal, antiplasmodial, hypoglycemic, minor tranquilizers, anti-asthmatic, antifungal, nematicidal, anti-amnestic and anti-arthritic. There are coincidences between some of the traditional usages of this plant and experimentally observed effects of the extracts but very few biological studies available on bioactive fractions and/or pure compounds. This review is an attempt to compile the exhaustive literature on Clerodendrum phlomidis, to highlight, analyze and critically assess the pharmaceutical potential of this underestimated plant in a systematic way.

Key words: Clerodendrum phlomidis , Bitters, Review literature, Medicine, Ayurvedic





Figure 1

Chemical structures of some isolated compounds from C. phlomidis (Ⅰ)"

Figure 2

Chemical structures of some isolated compounds from C. phlomidis (Ⅱ)"

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