Table 1

Body weight of rats at each time point [$\bar{x}$±s (n), g]"

Table 2

Lung quotient of rats [$\bar{x}$±s (n)]"

Table 3

Content of serum TGF-β1 in rats ($\bar{x}$±s, ng/L)"

Table 4

Content of serum PDGF in rats ($\bar{x}$±s, ng/L)"

Figure 1

Lung tissue pathology in sham-operated group (HE staining, ×100) The structure of lung was clear. There were no inflammatory cells in alveolar septum, and there were no inflammatory exudates in bronchial lumen and alveolar space."

Figure 2

Lung tissue pathology in sham-operated group (Masson staining, ×100) No pulmonary fibrosis was found."

Figure 3

Lung tissue pathology in BLM-treated group at 24 h of experiment (HE staining, ×100)"

Figure 4

Lung tissue pathology in BLM-treated group at 48 h of experiment (Masson staining, ×100)"

Figure 5

Lung tissue pathology in BLM-treated group on the 7th day of experiment (HE staining, ×100) The inflammation and fibroblast focuses were formed."

Figure 6

Lung tissue pathology in BLM-treated group on the 8th day of experiment (Masson staining, ×100) Deposit of collagen fibers could be seen."

Figure 7

Lung tissue pathology in BLM-treated group on the 14th day of experiment (HE staining, ×100) A great quantity of inflammatory cells could be seen in parts of the lung, and most of them were lymphocytes and eosinophile granulocytes."

Figure 8

Lung tissue pathology in BLM-treated group on the 14th day of experiment (HE staining, ×40) Inequality of cyst-like fiber air space could be seen in parts of the lung, i.e. the formation of honeycomb lung."

Figure 9

Lung tissue pathology in BLM-treated group on the 14th day of experiment (HE staining, ×100) Unequal deposit of collagen fibers in fibrosis area."

Figure 10

Lung tissue pathology in BLM-treated group on the 14th day of experiment (HE staining, ×200) Small amount of inflammatory cells in fibrosis area, and proliferation of typeⅡ alveolar epithelium could be seen."

Figure 11

Lung tissue pathology in BLM-treated group on the 28th day of experiment (HE staining, ×100) Obvious aggregation of macrophages in alveoli."

Figure 12

Lung tissue pathology in BLM-treated group on the 28th day of experiment (HE staining, ×100) Compared with lung tissue pathology on the 14th day of experiment, there were more cyst-like fiber air spaces."

Figure 13

Lung tissue pathology in BLM-treated group on the 14th day of experiment (Masson staining, ×100) Obvious fibrosis could be seen in parts of the lung."

Figure 14

Lung tissue pathology in BLM-treated group on the 28th day of experiment (Masson staining, ×100) The pulmonary fibrosis was more serious than that on the 14th day of experiment."

Figure 15

Lung tissue pathology in BLM-treated group on the 45th day of experiment (HE staining, ×200) Less inflammatory cells in fibrosis area and quantity of fibroblasts and collagen fibers could be seen."

Figure 16

Lung tissue pathology in BLM-treated group on the 45th day of experiment (Masson staining, ×200) The fibrosis was more serious than that on the 28th day of the experiment."