乳癌术后方对乳腺癌术后5年复发转移率的影响

doi:10.3736/jcim20081003

Abstract

Objective: To observe the effects of Ru'ai Shuhou Recipe (RSR), a compound traditional Chinese herbal medicine, on 5-year recurrence rate after mastectomy in breast cancer.
Methods: A total of 300 patients with breast cancer were divided into two groups: treatment group and control group. The patients in the treatment group were treated with Western medicine and RSR, and the patients in the control group were treated only with Western medicine (the same as the treatment group). In the two groups, the 5-year recurrence rates after mastectomy in breast cancer were investigated.
Results: Thirty-four breast cancer patients were lost to five-year follow-up during the course of investigation, and 266 breast cancer patients went through the evaluation. The 5-year recurrence rate after mastectomy in the treatment group was significantly lower than that in the control group (P<0.05). The recurrence rate after mastectomy was influenced by positive lymph node, primary breast tumor size, clinical stage, and patients' health status. There was significant difference in the 5-year recurrence rates between the two groups (P<0.05) under the following conditions, such as the positive lymph nodes more than four, the primary breast tumor larger than two centimeters, and in the clinical stage Ⅱ and Ⅲ, estrogen receptor (ER)-positive/progesterone receptor (PR)-positive and ER-negative/PR-negative. The recurrence rate was not associated with the operation method and age distribution.
Conclusion: RSR can reduce the 5-year recurrence rate after mastectomy in breast cancer.

Key words: breast cancer, recurrence, metastasis, Ruai Shuhou Recipe, traditional Chinese medicine

CLC Number:

R737.9

Sheng Liu, Jing Zhao, Jia Liu, Zhen-ping Sun, Yong-qiang Hua, De-ming Lu, Han-jun Tang. Effects of Ru'ai Shuhou Recipe on 5-year recurrence rate after mastectomy in breast cancer. Journal of Chinese Integrative Medicine, 2008, 6(10): 1000-1004.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20081003

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Effects of Ru'ai Shuhou Recipe on 5-year recurrence rate after mastectomy in breast cancer

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