Journal of Chinese Integrative Medicine ›› 2008, Vol. 6 ›› Issue (11): 1170-1173.doi: 10.3736/jcim20081112
• Original Experimental Research • Previous Articles Next Articles
Possible role of GABAA-benzodiazepine receptor in anticonvulsant effects of Pasipay in rats
Nassiri-Asl Marjan1(
), Zamansolt Farzaneh2, Shariati-R Schwann3
- 1. Department of Pharmacology, School of Medical Sciences, Qazvin University, Qazvin, Iran
2. Department of Anatomy, School of Medical Sciences, Qazvin University, Qazvin, Iran
3. School of Medical Sciences, Qazvin University, Qazvin, Iran
CLC Number:
- R971.6
| [1] |
Carlini EA . Plants and the central nervous system[J]. Pharmacol Biochem Behav, 2003,75(3):501-512
doi: 10.1016/S0091-3057(03)00112-6 pmid: 12895668 |
| [2] |
Soulimani R, Younos C, Jarmouni S , et al. Behavioural effects of Passiflora incarnata L. and its indole alkaloid and flavonoid derivatives and maltol in the mouse[J]. J Ethnopharmacol, 1997,57(1):11-20
doi: 10.1016/S0378-8741(97)00042-1 |
| [3] |
Capasso A, Sorrentino L . Pharmacological studies on the sedative and hypnotic effect of Kava kava and Passiflora extracts combination[J]. Phytomedicine, 2005,12(1-2):39-45
doi: 10.1016/j.phymed.2004.03.006 |
| [4] |
Akhondzadeh S, Naghavi HR, Vazirian M , et al. Passion flower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam[J]. J Clin Pharm Ther, 2001,26(5):363-367
doi: 10.1046/j.1365-2710.2001.00367.x |
| [5] |
Akhondzadeh S, Kashani L, Mobaseri M , et al. Passion flower in the treatment of opiates withdrawal: a double-blind randomized controlled trial[J]. J Clin Pharm Ther, 2001,26(5):369-373
doi: 10.1046/j.1365-2710.2001.00366.x |
| [6] |
Sejima H, Ito M, Kishi K , et al. Regional excitatory and inhibitory amino acid concentration in pentylenetetrazole kindling and kindled rat brain[J]. Brain Dev, 1997,19(3):171-175
doi: 10.1016/S0387-7604(96)00492-5 |
| [7] |
Nassiri-Asl M, Shariati-Rad S, Zamansoltani F .Anticonvulsant effects of aerial parts of Passiflora incarnata extract in mice: involvement of benzodiazepine and opioid receptors[J].BMC Complement Altern Med, 2007, 7: 26
doi: 10.1186/1472-6882-7-26 |
| [8] | Paxions G, Watson C. The rat brain in stereotaxic coordinates[M]. New York: Academic Press,1998: |
| [9] |
Nassiri-Asl M, Shariati-Rad S, Zamansoltani F . Anticonvulsive effects of intracerebroventricular administration of rutin in rats[J]. Prog Neuropsychopharmacol Biol Psychiatry, 2008,32(4):989-993
doi: 10.1016/j.pnpbp.2008.01.011 pmid: 18262708 |
| [10] |
Loscher W, Honack D, Fassbender CP , et al. The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. Ⅲ. Pentylenetetrazole seizure models[J]. Epilepsy Res, 1991,8(3):171-189
doi: 10.1016/0920-1211(91)90062-K |
| [11] |
Lolli LF, Sato CM, Romanini CV , et al. Possible involvement of GABAA-benzodiazepine receptor in the anxiolytic-like effect induced by Passiflora actinia extracts in mice[J]. J Ethnopharmacol, 2007,111(2):308-314
doi: 10.1016/j.jep.2006.11.021 |
| [12] |
Speroni E, Minghetti A . Neuropharmacological activity of extracts from Passiflora incarnata[J]. Planta Med, 1988,54(6):488-491
doi: 10.1055/s-2006-962525 pmid: 3212072 |
| [13] |
Fernández SP, Wasowski C, Loscalzo LM , et al. Central nervous system depressant action of flavonoid glycosides[J]. Eur J Pharmacol, 2006,539(3):168-176
doi: 10.1016/j.ejphar.2006.04.004 pmid: 16698011 |
| [14] |
Tsang SY, Xue H . Development of effective therapeutics targeting the GABAA receptor: naturally occurring alternatives[J]. Curr Pharm Des, 2004,10(9):1035-1044
doi: 10.2174/1381612043452767 |