Journal of Chinese Integrative Medicine ›› 2010, Vol. 8 ›› Issue (2): 173-180.doi: 10.3736/jcim20100213
• Original Experimental Research • Previous Articles Next Articles
Effects of Qishe Pill on vertebral hyperostosis induced by upright posture in rats
Qin Bian , Qian-qian Liang, Wei HOU, Yong-jian Zhao, Sheng Lu, Yong-jun Wang
,Qi Shi
- Institute of Spine, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
| [1] | Bian Q, Liang QQ, Hou W, Wang YJ, Shi Q . The effect of long-term upright posture on rats-lumbar hyperosteogeny[J]. Zhongguo Ji Zhu Ji Sui Za Zhi, 2009,19(1):60-63 |
| 卞琴, 梁倩倩, 侯炜, 王拥军, 施杞 . 长期直立和大鼠腰椎骨质增生的关系[J]. 中国脊柱脊髓杂志, 2009,19(1):60-63 | |
| [2] |
Liang QQ, Zhou Q, Zhang M, Hou W, Cui XJ, Li CG, Li TF, Shi Q, Wang YJ . Prolonged upright posture induces degenerative changes in intervertebral discs in rat lumbar spine[J]. Spine (Phila Pa 1976), 2008,33(19):2052-2058
doi: 10.1097/BRS.0b013e318183f949 |
| [3] |
Dankbar B, Neugebauer K, Wunrau C, Tibesku CO, Skwara A, Pap T, Fuchs-Winkelmann S . Hepatocyte growth factor induction of macrophage chemoattractant protein-1 and osteophyte-inducing factors in osteoarthritis[J]. J Orthop Res, 2007,25(5):569-577
doi: 10.1002/(ISSN)1554-527X |
| [4] |
van Lent PL, Blom AB, van der Kraan P, Holthuysen AE, Vitters E, van Rooijen N, Smeets RL, Nabbe KC, van den Berg WB . Crucial role of synovial lining macrophages in the promotion of transforming growth factor beta-mediated osteophyte formation[J]. Arthritis Rheum, 2004,50(1):103-111
doi: 10.1002/(ISSN)1529-0131 |
| [5] |
Hashimoto S, Creiqhton-Achermann L, Takahashi K, Amiel D, Coutts RD, Lotz M . Development and regulation of osteophyte formation during experimental osteoarthritis[J]. Osteoarthritis Cartilage, 2002,10(3):180-187
doi: 10.1053/joca.2001.0505 |
| [6] |
Blaney Davidson EN Vitters EL, van der Kraan PM, van den Berg WB. , Expression of transforming growth factor-beta(TGFbeta) and the TGFbeta signalling molecule SMAD-2P in spontaneous and instability-induced osteoarthritis: role in cartilage degradation, chondrogenesis and osteophyte formation[J]. Ann Rheum Dis, 2006,65(11):1414-1421
doi: 10.1136/ard.2005.045971 |
| [7] |
Robling AG, Castillo AB, Turner CH . Biomechanical and molecular regulation of bone remodelling[J]. Annu Rev Biomed Eng, 2006,8:455-498
doi: 10.1146/annurev.bioeng.8.061505.095721 |
| [8] |
Kuivaniemi H, Tromp G, Prockop DJ . Mutations in fibrillar collagens(types Ⅰ, Ⅱ, Ⅲ, and Ⅺ), fibril-associated collagen(type Ⅸ), and network-forming collagen(type Ⅹ) cause a spectrum of diseases of bone, cartilage, and blood vessels[J]. Hum Mutat, 1997,9(4):300-315
doi: 10.1002/(ISSN)1098-1004 |
| [9] |
Alliston T, Choy L, Ducy P, Karsenty G, Derynck R . TGF-beta-induced repression of CBFA1 by Smad3 decreases cbfa1 and osteocalcin expression and inhibits osteoblast differentiation[J]. EMBO J, 2001,20(9):2254-2272
doi: 10.1093/emboj/20.9.2254 |
| [10] | Nathan M, Pope MH, Grobler LJ . Osteophyte formation in the vertebral column: a review of the etiologic factors — Part Ⅱ[J]. Contemp Orthop, 1994,29(2):113-119 |
| [11] |
Scharstuhl A , Glansbeek HL, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB.Inhibition of endogenous TGF-beta during experimental osteoarthritis prevents osteophyte formation and impairs cartilage repair[J]. J Immunol, 2002,169(1):507-514
doi: 10.4049/jimmunol.169.1.507 |
| [12] |
Bakker AC, van de Loo FA, van Beuningen HM, Sime P, van Lent PL, van der Kraan PM, Richards CD, van den Berg WB . Overexpression of active TGF-beta-1 in the murine knee joint: evidence for synovial-layer-dependent chondro-osteophyte formation[J]. Osteoarthritis Cartilage, 2001,9(2):128-136
doi: 10.1053/joca.2000.0368 |
| [13] |
van Beuningen HM, Glansbeek HL, van der Kraan PM, van den Berg WB . Differential effects of local application of BMP-2 or TGF-beta 1 on both articular cartilage composition and osteophyte formation[J]. Osteoarthritis Cartilage, 1998,6(5):306-317
doi: 10.1053/joca.1998.0129 |
| [14] |
Hayami T, Pickarski M, Wesolowski GA McLane J, Bone A, Destefano J, Rodan GA, Duong le T. , The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model[J]. Arthritis Rheum, 2004,50(4):1193-1206
doi: 10.1002/(ISSN)1529-0131 |
| [15] | Scharstuhl A , Vitters EL, van der Kraan PM, van den Berg WB.Reduction of osteophyte formation and synovial thickening by adenoviral overexpression of transforming growth factor beta/bone morphogenetic protein inhibitors during experimental osteoarthritis[J]. Arthritis Rheum, 2004,48(12):3442-3451 |
| [16] | Wang YJ, Shi Q, Shen PZ, Xu Y, Wan C . Experimental study on effect of Qishejingkang Recipe on activity of alkaline phosphatases in osteophyte formation of degenerated cervical vertebrae of rabbits[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2000,20(3):199-201 |
| 王拥军, 施杞, 沈培芝, 徐宇, 万超 . 芪麝颈康方对兔退变颈椎骨赘形成部位碱性磷酸酶活性的影响[J]. 中国中西医结合杂志, 2000,20(3):199-201 |