中西医结合康复训练对慢性阻塞性肺疾病患者运动能力及生活质量的影响：随机对照临床试验

doi:10.3736/jcim20100506

Abstract

Background

Chronic obstructive pulmonary disease (COPD) is an important clinical disease, and its global prevalence and mortality rates are high. It is meaningful to investigate the efficacy of integrative respiratory rehabilitation training in quality of life and respiratory physiology of COPD patients in stable phase.
Objective

To observe the efficacy of integrative respiratory rehabilitation training in exercise ability and quality of life of COPD patients in stable phase.Design, setting, participants and interventions: Eighty outpatients and inpatients with COPD from Department of Respiratory Medicine, Taihe Hospital, Yunyang Medical College were randomly divided into 4 groups, with 20 patients in each group. The patients in group A only received drug therapy, the patients in group B received traditional qigong training, the patients in group C received modern rehabilitation training, and the patients in group D received integrative respiratory rehabilitation training.Main outcome measures: Chronic respiratory questionnaire (CRQ), 6-minute walking distance and Borg score in each group were examined before and after one-, three-, and six-month and one-year treatment.
Results

The 6-minute walking distance, Borg score and CRQ score in group A had no significant changes after treatment (P>0.05). After one-month treatment, there were no significant differences in 6-minute walking distance and Borg score in groups B, C and D as compared with those before treatment (P<0.05). After three-month treatment, 6-minute walking distance and Borg score were improved in groups B, C and D (P<0.05). After six-month and one-year treatment, 6-minute walking distance, Borg score and CRQ score in groups B, C and D were improved as compared with those before treatment (P<0.05), and there were significant differences between group D and any of groups A, B and C (P<0.05).
Conclusion

Modern rehabilitation training, traditional qigong training and integrative respiratory rehabilitation training programs all can improve the quality of life and exercise ability of COPD patients, and integrative respiratory rehabilitation training program is better than modern rehabilitation training and traditional qigong training programs. The efficacy of respiratory rehabilitation training is time-dependent, and need long-time adherence to the therapy.

Key words: Chronic obstructive pulmonary disease, Rehabilitation, Qigong, Quality of life, Randomized controlled trial

Yuan-hong Xu , Jun-hua Wang, Hai-feng Li , Xiao-hu Zhu, Gang Wang. Efficacy of integrative respiratory rehabilitation training in exercise ability and quality of life of patients with chronic obstructive pulmonary disease in stable phase: A randomized controlled trial. Journal of Chinese Integrative Medicine, 2010, 8(5): 432-437.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20100506

http://www.jcimjournal.com/EN/Y2010/V8/I5/432

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References 12

[1]	O'Donnell DE, Aaron S, Bourbeau J, Hernandez P, Marciniuk D, Balter M, Ford G, Gervais A, Goldstein R, Hodder R, Maltais F, Road J ; Canadian Thoracic Society.Canadian Thoracic Society recommendations for management of chronic obstructive pulmonary disease 2003[J]. Can Respir J, 2003,Suppl A: 11A-65A
[2]	Pauwels RA, Buist AS, Calverley PM, Jenkins CR, Hurd SS ; GOLD Scientific Committee.Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease(GOLD) Workshop summary[J]. Am J Respir Crit Care Med, 2001,163(5):1256-1276 doi: 10.1164/ajrccm.163.5.2101039
[3]	Ye RG, Lu ZY. Internal medicine(6th ed)[M]. Beijing: People's Medical Publishing House, 2004,( 6th ed):57-63
	叶任高, 陆再英 .内科学 ( 第6版)[M]. 北京: 人民卫生出版社, 2004,( 第6版):57-63
[4]	Group of Chronic Obstructive Pulmonary Diseases, Branch of Respiratory Disease of China Medical Association. Diagnosis and treatment guidance of chronic obstructive pulmonary diseases[J]. Zhonghua Jie He He Hu Xi Za Zhi, 2002,25(8):453-460
	中华医学会呼吸病学会慢性阻塞性肺疾病学组. 慢性阻塞性肺疾病诊治指南[J]. 中华结核和呼吸杂志, 2002,25(8):453-460
[5]	Guyatt GH, Berman LB, Townsend M, Pugsley SO, Chambers LW . A measure of quality of life for clinical trials in chronic lung disease[J]. Thorax, 1987,42(10):773-774 doi: 10.1136/thx.42.10.773
[6]	Zhao L, Liu RY . Study of home-based pulmonary rehabilitation program in development of chronic obstructive pulmonary disease[J]. Zhongguo Kang Fu Yi Xue Za Zhi, 2006,21(2):127-131
	赵磊, 刘荣玉 . 家庭肺康复运动训练方案在慢性阻塞性肺病发展中作用的研究[J]. 中国康复医学杂志, 2006,21(2):127-131
[7]	Liu PZ, Huang XX, Ren LX, Yao CL, Yang JP . Respiratory muscle training in improving pulmonary function and quality of life of COPD[J]. Lin Chuang Fei Ke Za Zhi, 2006,11(2):217-218
	刘鹏珍, 黄秀香, 任立新, 姚翠玲, 杨敬平 . 呼吸肌康复训练改善COPD的肺功能和生活质量[J]. 临床肺科杂志, 2006,11(2):217-218
[8]	Deng SK, Yang XQ, Li D, Zheng JL . Effects of respiratory training on pulmonary function in patients with chronic obstructive pulmonary disease in stable stage[J]. Xian Dai Yi Yao Wei Sheng, 2007,19(23):2853-2854
	邓述恺, 杨小琼, 李多, 郑俊兰 . 呼吸训练对慢性阻塞性肺病缓解期患者肺功能的影响[J]. 现代医药卫生, 2007,19(23):2853-2854
[9]	Wu XM, Hou LY, Bai W, Peng Y, Li Y, Xie YX, Sun QL, Lin JT . Effects of breathing training on quality of life and activities of daily living in elderly patients with stable severe chronic obstructive pulmonary disease[J]. Zhongguo Kang Fu Yi Xue Za Zhi, 2006,21(4):307-310
	吴学敏, 侯来永, 白伟, 彭越, 李月, 谢欲晓, 孙启良, 林江涛 . 呼吸训练对缓解期老年重度COPD患者生活质量及日常生活活动的影响[J]. 中国康复医学杂志, 2006,21(4):307-310
[10]	Pryor JA, Webber BA . Physiotherapy for respiratory and cardiac problems(2nd ed)[M]. New York: Churchill Livingstone Inc,, 1998,( 2nd ed):137-138
[11]	Tan T, Bi F, Yang XP, Mo XY, Xu JL, Tian SL, Liu W . Efficacy of breathing qigong therapy for pulmonary rehabilitation in patients with chronic obstructive pulmonary disease in stable phase[J]. Guiyang Zhong Yi Xue Yuan Xue Bao, 2007,29(6):34-35
	谭韬, 毕番, 杨秀萍, 莫小燕, 徐江玲, 田绍连, 刘炜 . 呼吸气功疗法对慢性阻塞性肺疾病稳定期患者肺康复的疗效研究[J]. 贵阳中医学院学报, 2007,29(6):34-35
[12]	Xu GH, Zhu J . Breathing exercise used in treatment of chronic obstructive pulmonary disease with deficiency of lung and kidney[J]. Nanjing Zhong Yi Yao Da Xue Xue Bao Zi Ran Ke Xue Ban, 2001,17(2):81-84
	徐桂华, 朱佳 . 呼吸功对COPD肺肾两虚患者康复治疗的研究[J]. 南京中医药大学学报自然科学版, 2001,17(2):81-84

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Group	n	Six-minute walking distance
Group	n	Before treatment	One-month treatment	Three-month treatment	Six-month treatment	One-year treatment
A	20	385.42±35.80	387.65±35.60	392.58±48.80	395.48±38.80	385.82±39.80
B	20	387.48±34.50	389.85±35.50	399.75±58.80^*△	430.56±41.80^*△	460.85±35.80^*△
C	20	386.42±35.50	388.75±35.45	395.85±60.50*△	428.26±42.50^*△	458.85±40.80^*△
D	20	385.82±28.50	394.85±35.40	422.85±58.50^*△▲□	458.36±45.50^*△▲□	485.85±42.80^*△▲□

Group	n	Brog score
Group	n	Before treatment	One-month treatment	Three-month treatment	Six-month treatment	One-year treatment
A	20	9.57±2.80	9.40±2.45	9.65±2.45	9.40±2.55	9.64±2.60
B	20	9.53±3.10	9.25±2.35	8.90±2.20^*△	8.60±3.35^*△	8.10±2.40^*△
C	20	9.46±3.00	9.15±2.50	8.81±2.35*△	8.50±2.50^*△	8.95±2.60^*△
D	20	9.45±3.00	9.03±2.20	8.65±2.15^*△▲□	8.20±2.20^*△▲□	8.40±2.10^*△▲□

Group	n	CRQ score
Group	n	Before treatment	One-month treatment	Three-month treatment	Six-month treatment	One year treatment
A	20	15.32±1.59	15.15±1.56	15.56±1.50	15.69±1.50	16.02±1.85
B	20	15.21±1.60	15.46±2.15	16.10±1.80	17.27±2.03^*	18.36±1.73^*
C	20	15.24±1.48	15.36±1.85	15.88±1.63	16.87±1.83^*	17.80±1.75^*
D	20	15.21±1.55	15.75±1.85	16.73±1.83	18.17±1.90^*△▲□	19.75±1.23^*△▲□

Efficacy of integrative respiratory rehabilitation training in exercise ability and quality of life of patients with chronic obstructive pulmonary disease in stable phase: A randomized controlled trial

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