Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2006, Vol. 4 ›› Issue (6): 644-648.doi: 10.3736/jcim20060621

• Original Experimental Research • Previous Articles     Next Articles

Effect of infrared laser on pituitrin-induced bradycardia in rabbits

Xue-yong Shen1, 4,Guang-hong Ding2, 4,Jian-ping Gap3,Ling Zhao1,Jian-zi Wei1,Hai-ping Deng1,Li-zhen Wang1   

  1. 1. College of Acupuncture and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
    2. Department of Mechanics and Applied Engineering, Fudan University, Shanghai 200433, China
    3. Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China
    4 Shanghai Research Center of Acupuncture and Meridian, Shanghai 201203, China
  • Online:2006-11-30 Published:2006-11-15

Objective

To observe the effect of infrared laser stimulation on Neiguan (PC 6) for bradycardia of rabbits induced by injection of pituitrin.

Methods

10.6 μm CO2 infrared laser, 650 nm semiconductor red laser and the compound laser of their aggregation were sent out by a compound laser sanatory instrument to stimulate Neiguan (PC 6) respectively for the purpose of analyzing the differences of the effects exerted by infrared laser and red laser as well as the changes of the effects after their aggregation.

Results

After 30 min and 40 min of the injection of pituitrin, the heart rate showed no significant difference between 10.6 μm CO2 infrared laser group and the normal control group (P>0.05). However, the heart rate showed significant difference between the 650 nm semiconductor red laser group and the normal control group (P<0.05). After 30 min of the injection of pituitrin, the heart rate of the compound laser group were significantly different to that of the untreated group (P<0.05), and it was not significantly different to that of the normal control group (P>0.05). However, the heart rate of non-acupoint stimulated by the compound laser group showed no significant difference to that of the untreated group (P>0.05), and it was significantly different to that of the normal control group (P<0.05).

Conclusion

Stimulation on Neiguan with 10.6 μm CO2 infrared laser can evidently improve the bradycardia induced by injection of pituitrin, while the 650 nm semiconductor red laser has no such function, but they have coordinating effect. The thermal effect produced by CO2 infrared laser stimulating acupoint is probably beneficial for semiconductor laser penetrating skin as well as the biochemical reactions it carries. The improvement of heart rate produced by the laser stimulation on Neiguan (PC6)has relative specificity.

Key words: Laser, Acupuncture, Acupoint, Neiguan (PC 6), Bradycardia

CLC Number: 

  • R245

Figure 1

Sketch map of compound laser apparatus"

Table 1

Changes of heart rate of rabbits (ヌ±S, heart beat/min)"

GroupnBefore pituitrin injectionAfter pituitrin injection
5 min10 min15 min20 min25 min30 min40 min
Normal control15252.40±29.06251.33±32.01243.93±35.28246.67±31.93241.33±34.81241.93±34.17239.13±33.57244.33±32.79
Untreated15273.47±47.60147.00±27.56*169.40±19.93*177.33±21.52*183.20±23.27*190.67±25.33*194.93±26.17*204.53±30.50*
10.6 μm laser Neiguan15278.67±34.98164.27±32.27*176.07±23.32*185.87±24.30*195.13±21.82*203.60±22.86*215.93±20.54226.60±21.88
650 nm laser Neiguan15269.40±47.50150.07±30.70*170.53±21.88*182.27±22.63*191.73±20.97*198.00±26.44*205.13±30.59*216.53±29.77*
Compound laser Neiguan15271.53±41.30155.20±29.19*179.73±28.76*192.20±33.48*199.07±32.95*209.47±35.56*217.67±38.16225.27±37.23
Compound laser non-acupoint15268.67±43.99140.87±24.28*163.47±20.18*172.93±19.81*183.53±20.27*193.33±21.11*203.20±22.51*220.20±26.84

Figure 2

Changes of heart rate before and after bradycardia induced by pituitrin"

[1] Whittaker P.Laser acupuncture: past, present, and future[J].Lasers Med Sci,2004,19(2):69-80
doi: 10.1007/s10103-004-0296-8 pmid: 15349795
[2] 高建平, 卞蓓亚, 陈惠民, 等.卤化银多晶光纤传输CO2激光性能的研究[J].无机材料学报,2000,15(1):119-123
doi: 10.3321/j.issn:1000-324X.2000.01.021
[3] 朱愉, 多秀瀛.实验动物的基本模型(第1版)[M].天津: 天津科技翻译出版公司,1997,(第1版):158
[4] 邓春雷, 殷克敬.实验针灸学(第1版)[M].北京: 人民卫生出版社,1998,(第1版):142-143
[5] 李忠明, 张镇西.激光针灸治疗机理探讨[J].激光生物学报,2005,14(1):8-11
[6] Stadler I, Lanzafame RJ, Oskoui P, et al.Alteration of skin temperature during low-level laser irradiation at 830 nm in a mouse model[J].Photomed Laser Surg,2004,22(3):227-231
doi: 10.1089/1549541041438560 pmid: 15315730
[7] 沈雪勇, 丁光宏, 褚君浩, 等.传统艾灸与替代物灸和人体穴位红外辐射光谱比较[J].红外与毫米波学报,2003,22(2):123-126
[8] 沈恂. 生命科学中的物理问题讲座, 第九讲, 生物光子的相干性[J].物理,1995,24(3):166-171
[9] 邓海平, 沈雪勇, 丁光宏, 等.冠心病患者神门穴红外辐射光谱检测[J].上海针灸杂志,2004,23(11):31-34
[10] 魏建子, 沈雪勇, 丁光宏, 等.太渊穴自发红外辐射光谱研究[J].上海中医药大学学报,2004,18(4):33-35
doi: 10.3969/j.issn.1008-861X.2004.04.012
[11] 应荐, 沈雪勇, 刘汉平, 等.冠心病患者与正常人太冲穴红外辐射光谱比较[J].浙江中医杂志,2005,40(3):100-101
[12] 李忠明. 激光针灸的物理基础[J].应用激光,1999,19(6):376-378
[13] Makihara E, Makihara M, Masumi S, et al.Evaluation of facial thermographic changes before and after low-level laser irradiation[J].Photomed Laser Surg,2005,23(2):191-195
doi: 10.1089/pho.2005.23.191 pmid: 15910185
[1] Chiung-Hui Huang, Mei-Ling Yeh, Fang-Pey Chen, Daphne Wu. Low-level laser acupuncture reduces postoperative pain and morphine consumption in older patients with total knee arthroplasty: A randomized placebo-controlled trial. Journal of Integrative Medicine, 2022, 20(4): 321-328.
[2] Ming-min Xu, Pei Guo, Qing-yu Ma, Xuan Zhou, Yu-long Wei, Lu Wang, Yue Chen, Yu Guo. Can acupuncture enhance therapeutic effectiveness of antidepressants and reduce adverse drug reactions in patients with depression? A systematic review and meta-analysis. Journal of Integrative Medicine, 2022, 20(4): 305-320.
[3] Yen-Lin Chao, Yi-Ai Rau, Hong-Sheng Shiue, Jiun-Lin Yan, Yuan-Yun Tang, Shao-Wen Yu, Bo-Yan Yeh, Yen-Lung Chen, Tsung-Hsien Yang, Shu-Chen Cheng, Yi-Wen Hsieh, Hsin-Chia Huang, Fu-Kuang Tsai, Yu-Sheng Chen, Geng-Hao Liu. Using a consensus acupoints regimen to explore the relationship between acupuncture sensation and lumbar spinal postoperative analgesia: A retrospective analysis of prospective clinical cooperation. Journal of Integrative Medicine, 2022, 20(4): 329-337.
[4] Sergey Filist, Riad Taha Al-Kasasbeh, Olga Shatalova, Nikolay Korenevskiy, Ashraf Shaqadan, Zeinab Protasova, Maksim Ilyash, Mikhail Lukashov. Biotechnical system based on fuzzy logic prediction for surgical risk classification using analysis of current-voltage characteristics of acupuncture points. Journal of Integrative Medicine, 2022, 20(3): 252-264.
[5] Ting-ting Lu, Cun-cun Lu, Mei-xuan Li, Li-xin Ke, Hui Cai, Ke-hu Yang. Reporting and methodological quality of meta-analyses of acupuncture for patients with migraine: A methodological investigation with evidence map. Journal of Integrative Medicine, 2022, 20(3): 213-220.
[6] Xiang-yu Wei, Shi-lei Luo, HuiChen, Shan-shan Liu, Zhi-gang Gong, Song-huaZhan. Functional connectivity changes during migraine treatment with electroacupuncture at Shuaigu (GB8). Journal of Integrative Medicine, 2022, 20(3): 237-243.
[7] Samwel Sylvester Msigwa, Yan Li, Xiang-lin Cheng, Fen Cao. Combining electroacupuncture and transcranial direct current stimulation as an adjuvant therapy enhances spontaneous conversation and naming in subacute vascular aphasia: A retrospective analysis. Journal of Integrative Medicine, 2022, 20(3): 244-251.
[8] Xiao Ye, Yu-lan Ren, Yun-hui Chen, Ji Chen, Xiao-jiao Tang, Zong-ming Zhang. A "4D" systemic view on meridian essence: Substantial, functional, chronological and cultural attributes. Journal of Integrative Medicine, 2022, 20(2): 96-103.
[9] Bin Zhao, Yong Chen, Shi-min Liao, Jian-ying Zheng, Shi-hua Yan, Dong-shu Zhang. Successfully treated recalcitrant atopic eczema with acupoint autohemotherapy: A case report and hypothesized mechanism of the therapy. Journal of Integrative Medicine, 2022, 20(2): 182-186.
[10] Jun-peng Yao, Li-ping Chen, Xian-jun Xiao, Ting-hui Hou, Si-yuan Zhou, Ming-min Xu, Kai Wang, Yu-jun Hou, Lin Zhang, Ying Li. Effectiveness and safety of acupuncture for treating functional constipation: An overview of systematic reviews. Journal of Integrative Medicine, 2022, 20(1): 13-25.
[11] Xin Yin, Shu-bin Cai, Lan-ting Tao, Lu-ming Chen, Zhong-de Zhang, Su-hong Xiao, Arthur Yin Fan, Xu Zou. Recovery of a patient with severe COVID-19 by acupuncture and Chinese herbal medicine adjuvant to standard care. Journal of Integrative Medicine, 2021, 19(5): 460-466.
[12] Thomas Efferth, An-long Xu, Roxana Damiescu, Mita Banerjee, Norbert W. Paul, David Y.W. Lee. Can eastern wisdom resolve western epidemics? Traditional chinese medicine therapies and the opioid crisis. Journal of Integrative Medicine, 2021, 19(4): 295-299.
[13] Wen-jing Li, Chao Gao, Li-xin An, Yu-wei Ji, Fu-shan Xue, Yi Du. Perioperative transcutaneous electrical acupoint stimulation for improving postoperative gastrointestinal function: A randomized controlled trial. Journal of Integrative Medicine, 2021, 19(3): 211-218.
[14] Qiu-yu Tong, Ran Liu, Kun Zhang, Yuan Gao, Guang-wei Cui, Wei-dong Shen. Can acupuncture therapy reduce preoperative anxiety? A systematic review and meta-analysis. Journal of Integrative Medicine, 2021, 19(1): 20-28.
[15] Xian Wang, Xuan Yin, Xiu-tian Guo, Yan Wang, Wen-qi Jin, Ai-jun Mao, Lixing Lao, Zhang-jin Zhang, Jie Zhang, Shi-fen Xu. Effects of the pestle needle therapy, a type of acupoint stimulation, on post-hemorrhoidectomy pain: A randomized controlled trial. Journal of Integrative Medicine, 2020, 18(6): 492-498.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Jin-rong Fu. Establishment of multivariate diagnosis and treatment system of modern gynecology of traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 22-24
[2] Hao Li, Ming-jiang Yao, Wen-ming Zhao, Jie Guan, Lin-lin Cai, Ling Cui. A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment. Journal of Chinese Integrative Medicine, 2008, 6(1): 25-31
[3] Zhi-chun Jin. Problems in establishing clinical guideline for integrated traditional Chinese and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 5-8
[4] SUN Ming-yu, ZUO Jian, DUAN Ji-feng, HAN Jun, FAN Shi-ming, ZHANG Wei, ZHU Li-fang, YAO Ming-hui. Antitumor activities of kushen flavonoids in vivo and in vitro. Journal of Chinese Integrative Medicine, 2008, 6(1): 51-59
[5] Min Cheng, Qiong Feng, Shu-wen Qian, Hui Gao, Cui-qing Zhu. Preliminary assay of p-amyloid binding elements in heart-beneficial recipe. Journal of Chinese Integrative Medicine, 2008, 6(1): 68-72
[6] Ning-qun Wang, Liang-duo Jiang, Zong-xing Li. Research progress in asthma-related quality of life. Journal of Chinese Integrative Medicine, 2008, 6(1): 93-97
[7] Jing-yuan Mao, Chang-xiao Liu, Heng-he Wang, Guang-li Wei , Zhen-peng Zhang, Jie Xing, Wang Xian liang , Ying-fei Bi . Effects of Shenmai Injection on serum concentration and pharmacokinetics of digoxin in dogs with heart failure. Journal of Chinese Integrative Medicine, 2010, 8(11): 1070-1074
[8] Zhi-mei Wang, Bin Zhang. A study on translation of ellipses in Huangdi Neijing from perspective of hermeneutic theory. Journal of Chinese Integrative Medicine, 2010, 8(11): 1097-1100
[9] Gui Yu, Jie Wang. Thinking on building the network cardiovasology of Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(11): 1206-1210
[10] Pedro Saganha João, Doenitz Christoph, Greten Tobias, Efferth Thomas, J. Greten Henry. Qigong therapy for physiotherapists suffering from burnout: a preliminary study. Journal of Chinese Integrative Medicine, 2012, 10(11): 1233-1239