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Journal of Chinese Integrative Medicine ›› 2007, Vol. 5 ›› Issue (5): 494-496.doi: 10.3736/jcim20070502

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Influence of Lithospermum on pregnancy

Zi-fei Yin1, Yu-zhi Hu2, Yong-hua Su3   

  1. 1. School of Traditional Chinese Medicine , Second Military Medical University , Shanghai 200433 , China
    2. Children's Rehabilitation Center , Hospital of Maternal and Child Health , Linyi , Shandong Province 276001 , China
    3. Department of Traditional Chinese Medicine , Changhai Hospital ; Teaching and Research Group of Chinese Herbal Medi-cines and Formulae , School of Traditional Chinese Medicine , Second Military Medical University , Shanghai 200433 , China
  • Online:2007-09-20 Published:2007-09-15

Lithospermum has been widely used in clinic for a long time. It can lower the levels of follicle stimulating hormone and luteinizing hormone in blood serum and inhibit ovulation, thus causing infertility. Due to its effect of lowering chorionic gonadotropin, restraining the development of corpus luteum graviditatis and interfering the growth of uterus and the supply of embryotrophy, Lithospermum has been confirmed to be effective in termination of pregnancy and herb abortion. Therefore Lithospermum can not be used in those who intend to conceive or do not need to terminate pregnancy. The authors suggest that the influence of Lithospermum on pregnancy should be studied objectively and should be emphasized in clinical teaching of traditional Chinese medicine to ensure the correct and reasonable application of Lithospermum.

Key words: Li thospermum, pregnancy, contraindication

CLC Number: 

  • R169.441
[1] 高晓山 . 中药妊娠禁忌药的研究进展和动向.[J]. 广西中医学院学报, 2001,4(4):8-9
Gao XS . Research development and trends of herbal medicines contraindication to gravida[J]. Guangxi Zhong Yi Xue Yuan Xue Bao, 2001,4(4):8-9
[2] 宋立人, 洪恂, 丁绪亮 , 等. 现代中药学大辞典(第1版)[M]. 北京: 人民卫生出版社, 2001,( 第1版):2132-2136
Song LR, Hong X, Ding XL , et al. Modern dictionary of Chinese materia medica(1st ed)[M]. Beijing: People's Health Publishing House, 2001,( 1st ed):2132-2136
[3] 肖培根, 李大鹏, 杨世林 . 新编中药志(第1版)[M]. 北京: 化学工业出版社, 2002,( 第1版):976-986
Xiao PG, Li DP, Yang SL. Modern Chinese materia medica(1st ed)[M]. Beijing: Chemical Industry Press, 2002,( 1st ed):976-986
[4] 罗学娅, 李明辉, 吕莉 , 等. 紫草的药理作用与应用研究进展[J]. 大连大学学报, 2004,25(2):80-83, 92
Luo XY, Li MH, Lu L , et al. Research progress of pharmacological action and application of Lithospermum erythrorhizon Sieb.et Zucc[J]. Dalian Da Xue Xue Bao, 2004,25(2):80-83, 92
[5] 高晓山 . 中药药性论(第1版)[M]. 北京: 人民卫生出版社, 1992,( 第1版):138-150
Gao XS. Properties and action of Chinese materia medica(1st)[M]. Beijing: People's Health Publishing House, 1992,( 1st):138-150
[6] Cranston EM . The effect of Lithospermum ruderale on the estrous cycle of mice[J]. Pharmacol Exp Ther, 1945,( 83):130-142
[7] Findley WE, Jacobs BR . The antigonadotropic activity of Lithospermum ruderale I. The lack of steroid-like activity at the receptor level[J]. Contraception, 1980,21(2):199-205
[8] 马保华, 邴鲁军, 王哲民 , 等. 中药紫草抗生育作用的研究[J]. 山东医科大学学报, 1993,31(1):34-36
Ma BH, LJ, Wang ZM , et al. Bing Study of Chinese herb Lithospermum for antifertility[J]. Shandong Yi Ke Da Xue Xue Bao, 1993,31(1):34-36
[9] 杨柳, 王秀华, 张西玲 , 等. 紫草乙醇提取物对体外培养人绒毛组织分泌HCG功能的影响[J]. 甘肃中医学院学报, 2001,18(1):21-23
Yang L, Wang XH, Zhang XL , et al. The effect of Lithospermum extracted by ethyl alocohol on the function of trophonema tissue's secreting HCG in vitro culture[J]. Gansu Zhong Yi Xue Yuan Xue Bao, 2001,18(1):21-23
[10] 刘建华, 法辒玉, 孙桦 , 等. 紫草辅助米非司酮抗早孕对生殖激素的影响[J]. 生殖医学杂志, 2000,9(3):155-158
Liu JH, Fa YY, Sun H , et al. The influence of Lithospermum ruderale on medical abortion with mifepristone and misoprostol[J]. Sheng Zhi Yi Xue Za Zhi, 2000,9(3):155-158
[11] 刘建华, 王萍 . 紫草辅助早期妊娠药物流产200例临床观察[J]. 中国实用妇科与产科杂志, 2002,18(6):365-366
Liu JH, Wang P . Clinical observation of 200 examples: The effect of Lithospermum in the drug abortion in early pregnancy[J]. Zhongguo Shi Yong Fu Ke Yu Chan Ke Za Zhi, 2002,18(6):365-366
[12] 刘淑娟 . 中药紫草缩短药物流产阴道出血时间临床观察[J]. 深圳中西医结合杂志, 2003,13(2):100-101
Liu SJ . Clinical observation of Lithospermum's decurtating the bleeding time of vagina after drug abortion[J]. Shenzhen Zhong Xi Yi Jie He Za Zhi, 2003,13(2):100-101
[13] 刘发, 李观海, 郑明新 , 等. 新疆紫草对动物抗早孕作用的初步研究[J]. 新疆医学院学报, 1982,5(3-4):199-200
Liu F, Li GH, Zheng MX , et al. Initial research on the effect of arnebia root's anti-early pregnancy[J]. Xinjiang Yi Xue Yuan Xue Bao, 1982,5(3-4):199-200
[14] 曹路敏, 毛惠益, 肖邦宙 , 等. 紫草抗人绒毛膜促性腺激素及抗早孕作用的实验观察[J]. 武汉医学院学报, 1985,14(4):280-282
Cao LM, Mao HY, Xiao BZ , et al. Experimental observation on the anti-HCG and early pregnancy terminating effects of arnebia euchroma[J]. Wuhan Yi Xue Yuan Xue Bao, 1985,14(4):280-282
[15] 李缓 . 大剂量紫草在非手术治疗异位妊娠中杀胚作用的临床观察[J]. 云南中医中药杂志, 1999,20(1):28
Li H . Clinical observation on the embryon terminating effect of large dose of Lithospermum in nonoperation treatment of eccyesis[J]. Yunnan Zhong Yi Zhong Yao Za Zhi, 1999,20(1):28
[16] 裴宪武, 王坤正, 党晓谦 , 等. 紫草油剂促进兔创面修复及碱性成纤维细胞生长因子表达[J]. 中西医结合学报, 2006,4(1):52-55
Pei XW, Wang KZ, Dang XQ , et al. Arnebia root oil promotes wound healing and expression of basic fibroblast growth factor on the wound surface in rabbits[J]. Zhong Xi Yi Jie He Xue Bao, 2006,4(1):52-55
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