Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2003, Vol. 1 ›› Issue (3): 177-179.doi: 10.3736/jcim20030309

Previous Articles     Next Articles

A review of experimental designs of compound compatibility law of traditional Chinese medicine

Xiao-li Song1, Yan-qing Gao1, Xin Niu1, Yin-chu Si2   

  1. 1. Department of Physiology, Beijing University of Traditional Chinese Medicine, Beijing 100029, China
    2. Department of Anatomy, Beijing University of Traditional Chinese Medicine, Beijing 100029, China
  • Received:2003-07-02 Online:2003-09-20 Published:2003-09-20

The paper discussed a variety of experimental designs of compound compatibility law of traditional Chinese medicine (TCM): study of whole formula and different ingredients of formula.The latter includes study of single ingredient, study of functional ingredient group, orthogonal design, clustering analysis, homogeneous design, factorial analysis and so on. It was proposed that experimental designs of formula should be based on the theory of TCM, and combined with modern sciences.

Key words: formula, compound compatibility law, experimental design

CLC Number: 

  • R289.1
[1] 张清苓, 刘渡舟, 贲长恩 . 桂枝汤调补脾胃的实验研究——大鼠实验性胃溃疡的治疗及肝、胃、肾组织化学的定量分析[J]. 北京中医药大学学报, 1994,17(3):24-27
doi: 10.1007/BF02007173
[2] 王昕 . 大黄虫丸的研究及应用概况[J]. 中成药, 1997,19(2):45-46
[3] 裴妙荣, 王世民, 廖晖 , 等. 薄层扫描法对四逆汤配伍作用的化学分析[J]. 中成药, 1993,15(6):33-35
[4] 吕景山 . 施今墨对药临床经验集(第1版)[M]. 太原: 山西人民出版社, 1982,( 第1版):26
[5] 吴建新, 严永清, 蒋莹 . 六味地黄汤的化学研究[J]. 现代应用药学, 1990,7(1):16-18
[6] 蒋莹, 赵陆华, 严永清 , 等. 六味地黄汤及其配伍对过氧化脂质及脂褐质含量的影响[J]. 中国中药杂志, 1991,16(3):175-176
[7] 黄黎, 刘菊福, 李德凤 , 等. 黄芩汤的组方配伍研究[J]. 中国中药杂志, 1991,16(3):177-181
[8] 宋宗华, 戴舒佳, 黎辉琴 , 等. 苓桂术甘汤配伍机制研究[J]. 中国中药杂志, 2002,27(10):760-762
[9] 苏薇薇 . 中药方剂的计算机辅助分析[J]. 中国中药杂志, 1997,22(3):186-188
[10] 林桂涛, 尹宁宁, 马承严 . 灰色系统理论与均匀设计结合在补阳还五汤处方筛选中的应用[J]. 中国实验方剂学杂志, 1997,3(4):16-20
[11] 王庆国, 李宇航, 赵琰 , 等. 半夏泻心汤及其拆方对正常大鼠胃肠运动功能的影响[J]. 北京中医药大学学报, 2001,24(6):19-21
[1] Wan-jun Guo, Yi Wang, Yu Deng, Lin-yan Cheng, Xin Liu, Ruo-fan Xi, Sheng-jie Zhu, Xin-yi Feng, Liang Hua, Kan Ze, Jian-yong Zhu, Dong-jie Guo, Fu-lun Li. Therapeutic effects of the extract of Sancao Formula, a Chinese herbal compound, on imiquimod-induced psoriasis via cysteine-rich protein 61. Journal of Integrative Medicine, 2022, 20(4): 376-384.
[2] Cai-lian Fana, Wan-jun Caib, Meng-nan Ye, Miao Chen, Yi Dai. Qili Qiangxin, a compound herbal medicine formula, alleviates hypoxia-reoxygenation-induced apoptotic and autophagic cell death via suppression of ROS/AMPK/mTOR pathway in vitro. Journal of Integrative Medicine, 2022, 20(4): 365-375.
[3] Mohammad Fazil, Sadia Nikhat. Why the “sugars” in traditional Unani formulations are a pivotal component: A viewpoint perspective. Journal of Integrative Medicine, 2022, 20(2): 91-95.
[4] Jia-jia Li, Qing Liang, Guang-chun Sun. Traditional Chinese medicine for prevention and treatment of hepatocellular carcinoma: A focus on epithelial-mesenchymal transition. Journal of Integrative Medicine, 2021, 19(6): 469-477.
[5] Sutticha Ruangchuay, Qiang-qiang Wang, Liang-yi Wang, Jing Lin, Yong-chao Wang, Guo-huan Zhong, Katesarin Maneenoon, Ze-bo Huang, Sasitorn Chusri. Antioxidant and antiaging effect of traditional Thai rejuvenation medicines in Caenorhabditis elegans . Journal of Integrative Medicine, 2021, 19(4): 362-373.
[6] Ju-Yeon Park, Young-Won Kwon, Sun-Ah Kim, Sun-Dong Park, Chang-Hyun Kim, Jin-Hee Kim, Ju-Hee Lee. Polyherbal formula SC-E3 inhibits rheumatoid arthritis activity in a mouse model of type-II collagen-induced arthritis. Journal of Integrative Medicine, 2021, 19(3): 265-273.
[7] Seung-hoon Choi. A digital application for implementing the ICD-11 traditional medicine chapter. Journal of Integrative Medicine, 2020, 18(6): 455-458.
[8] Jian-sheng Li, Xue-fang Liu, Hao-ran Dong, Wan-chun Zheng, Su-xiang Feng, Yan-ge Tian, Peng Zhao, Jin-di Ma, Zhou-xin Ren, Yang Xie. Effective-constituent compatibility-based analysis of Bufei Yishen formula, a traditional herbal compound as an effective treatment for chronic obstructive pulmonary disease. Journal of Integrative Medicine, 2020, 18(4): 351-362.
[9] Zi-jia Zhang, Wen-yong Wu, Jin-jun Hou, Lin-lin Zhang, Fei-fei Li, Lei Gao, Xing-dong Wu, Jing-ying Shi, Rong Zhang, Hua-li Long, Min Lei, Wan-ying Wu, De-an Guo, Kai-xian Chen, Lewis A. Hofmann, Zhonghua Ci. Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: network-molecular docking-LC-MSE analysis. Journal of Integrative Medicine, 2020, 18(3): 229-241.
[10] Deepak Kumar Semwal, Ashutosh Chauhan, Ankit Kumar, Sonali Aswal, Ruchi Badoni Semwal, Abhimanyu Kumar. Status of Indian medicinal plants in the International Union for Conservation of Nature and the future of Ayurvedic drugs: Shouldn’t think about Ayurvedic fundamentals?. Journal of Integrative Medicine, 2019, 17(4): 238-243.
[11] Sandip B. Bharate, Vikas Kumar, Sonali S. Bharate, Bikarma Singh, Gurdarshan Singh, Amarinder Singh, Mehak Gupta, DeepikaSingh, AjayKumar, Surjeet Singh, Ram A. Vishwakarma. Discovery and preclinical development of IIIM-160, a Bergenia ciliata-based anti-inflammatory and anti-arthritic botanical drug candidate. Journal of Integrative Medicine, 2019, 17(3): 192-204.
[12] Jesmin Mondal, Jayeeta Das, Rajesh Shah, Anisur Rahman Khuda-Bukhsh. A homeopathic nosode, Hepatitis C 30 demonstrates anticancer effect against liver cancer cells in vitro by modulating telomerase and topoisomerase II activities as also by promoting apoptosis via intrinsic mitochondrial pathway. Journal of Integrative Medicine, 2016, 14(3): 209-218.
[13] Amrita Mishra, Arun K.Mishra, Om Prakash Tiwari, Shivesh Jha. Studies on metals and pesticide content in some Ayurvedic formulations containing Bacopa monnieri L.. Journal of Integrative Medicine, 2016, 14(1): 44-50.
[14] Gang Guo, Jian-hua Xu, Jian-hong Han, Fang Liang, Yong Zhang, Qiang Zhang, Jue Sun, Zhong-ze Fan . Chinese herbal decoction Shiquan Dabu Tang inhibits tumor growth and angiogenesis of metastasis after primary tumor surgical removal in mice. Journal of Chinese Integrative Medicine, 2012, 10(4): 436-447.
[15] Xing-jiang Xiong, Jie Wang. Experience of diagnosis and treatment of exogenous high-grade fever. Journal of Chinese Integrative Medicine, 2011, 9(6): 681-687.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Wei-xiong Liang. Problems-solving strategies in clinical treatment guideline for traditional Chinese medicine and integrative medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 1-4
[2] Zhao-guo Li. Discussion on English translation of commonly used sentences in traditional Chinese medicine: part one. Journal of Chinese Integrative Medicine, 2008, 6(1): 107-110
[3] Jun Hu, Jian-ping Liu. Non-invasive physical treatments for chronic/recurrent headache. Journal of Chinese Integrative Medicine, 2008, 6(1): 31
[4] . Uniform requirements for manuscripts submitted to biomedical journals: Writing and editing for biomedical publication (Chinese version, part two). Journal of Chinese Integrative Medicine, 2010, 8(11): 1001-1005
[5] Daniel Weber, Janelle M Wheat, Geoffrey M Currie. Inflammation and cancer: Tumor initiation, progression and metastasis,and Chinese botanical medicines. Journal of Chinese Integrative Medicine, 2010, 8(11): 1006-1013
[6] Hong Liu , Guo-liang Zhang, Li Shen , Zhen Zeng, Bao-luo Zhou, Cheng-hai Liu, Guang Nie . Application and evaluation of a pseudotyped virus assay for screening herbs for anti-H5Nl avian influenza virus. Journal of Chinese Integrative Medicine, 2010, 8(11): 1036-1040
[7] Zhao-guo Li . A discussion of English translation of 1995 and 1997 Chinese National Standards of Traditional Chinese Medical Terminologies for Clinical Diagnosis and Treatment. Journal of Chinese Integrative Medicine, 2010, 8(11): 1090-1096
[8] Rui Jin, Bing Zhang. A complexity analysis of Chinese herbal property theory: the multiple formations of herbal property (Part 1). Journal of Chinese Integrative Medicine, 2012, 10(11): 1198-1205
[9] Hui-min Liu, Xian-bo Wang, Yu-juan Chang, Li-li Gu. Systematic review and meta-analysis of randomized controlled trials of integrative medicine therapy for treatment of chronic severe hepatitis. Journal of Chinese Integrative Medicine, 2012, 10(11): 1211-1228
[10] Liang-ping Hu, Xiao-lei Bao. Three-factor designs unable to examine the interactions (Part 2). Journal of Chinese Integrative Medicine, 2012, 10(11): 1229-1232