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Journal of Chinese Integrative Medicine ›› 2003, Vol. 1 ›› Issue (3): 192-194.doi: 10.3736/jcim20030314

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Clinical observation on treatment for postoperative metastasis of gastric cancer by Jianpi Huoxue Jiedu prescription

You-qi Xu(), Hui-ning Xue, Xiao-qiu Zhu, Xiao-dong Chen   

  1. Department of Oncology, Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing,Jiangsu Province 210028, China
  • Received:2003-05-06 Online:2003-09-20 Published:2003-09-20

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Objective

To study the effect of Jianpi Huoxue Jiedu (JPHXJD) prescription on prevention of the postoperative metastasis of gastric cancer and to observe the changes of immunity and whole blood viscosity after treatment.


Methods

JPHXJD prescription and chemotherapy were administered to the treated group for 12 successive months, while only chemotherapy was given to the control group.


Results

The effective rate of anti-metastasis in the treated group was obviously better than that in the control group. In the aspects of enhancing Karnofsky scores, reducing whole blood viscosity and improving immunity after treatment, the treated group was better than the control group (P<0.05).


Conclusion

JPHXJD prescription combined with chemotherapy shows apparent effect on anti-metastasis. It can improve the quality of life of the patients, lower the whole blood viscosity and improve the immunity function.

Key words: drugs, Chinese herbal, chemotherapy, neoplasm metastasis, stomach neoplasms, postoperative period, quality of life, whole blood viscosity, immunity

CLC Number: 

  • R735.2

"

组 别 n 血浆黏度
（mPa·s）		 全血黏度（低切）
（mPa·s）		 血沉方程
（K值）		 红细胞聚集指数 纤维蛋白原
（g/L）
治疗组 治疗前
治疗后		 42
42		 1.59±0.14
1.36±0.11*		 12.50±0.15
9.98±1.02*		 75.21±6.2
50.48±8.21*		 2.80±0.82
1.99±0.45		 3.92±0.12
2.34±0.18*
对照组 治疗前
治疗后		 30
30		 1.48±0.12
1.68±0.14△		 9.96±1.32
11.18±1.42△		 65.26±8.81
79.35±7.62△		 2.62±0.20
2.98±0.45△		 3.24±1.08
3.78±0.32△

"

组 别 n CD3（%） CD4（%） CD8（%） CD4/CD8 T淋巴细胞转化率（%）
治疗组 治疗前
治疗后		 42
42		 54.35±3.12
60.24±4.52*		 31.82±3.05
39.23±3.82*		 24.57±2.08
24.21±3.89*		 1.36±0.22
1.62±0.42*		 58.88±5.62
65.78±6.78*
对照组 治疗前
治疗后		 30
30		 55.52±3.18
51.20±4.87△		 32.24±3.28
30.92±3.92△		 25.28±2.90
27.63±3.03△		 1.31±0.19
1.19±0.25△		 69.27±5.79
58.82±9.26△
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