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Journal of Integrative Medicine ›› 2015, Vol. 13 ›› Issue (4): 209-211.doi: 10.1016/S2095-4964(15)60184-4

• Commentary •     Next Articles

The methodology flaws in Hinman’s acupuncture clinical trial, Part III: Sample size calculation

Arthur Yin Fan   

  1. McLean Center for Complementary and Alternative Medicine, PLC., Vienna, VA 22182, USA
  • Received:2015-02-12 Accepted:2015-03-26 Online:2015-07-10 Published:2015-07-15


Key words: Acupuncture, Chronic knee pain, Hinman, Sample size, Clinical trial, Flaws

[1] Hinman RS, McCrory P, Pirotta M, Relf I, Forbes A, Crossley KM, Williamson E, Kyriakides M, Novy K, Metcalf BR, Harris A, Reddy P, Conaghan PG, Bennell KL . Acupuncture for chronic knee pain: a randomized clinical trial[J]. JAMA, 2014,312(13):1313-1322
doi: 10.1136/acupmed-2014-010727
[2] Fan AY . The methodology flaws in Hinman’s acupuncture clinical, Part I: Design and results interpretation[J]. J Integr Med, 2015,13(2):65-68
doi: 10.1016/S2095-4964(15)60170-4
[3] Fan AY . The methodology flaws in Hinman’s acupuncture clinical trial, Part II: Zelen design and effectiveness dilutions. J Integr Med. 2015 April; Epub ahead of print.
[4] White A, Cummings M . Acupuncture for knee osteoarthritis: study by Hinman et al represents missed opportunities[J]. Acupunct Med, 2015,33(1):84-86
doi: 10.1136/acupmed-2014-010719
[5] National Institute for Health and Care Excellence (NICE). Osteoarthritis: care and management in adults. (2014-02)[ 2015-04-05]. .
[6] Dallal J. Approximate sample size calculator: comparing two means. (2012-05-23)[ 2015-04-05]. .
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[8] Friedman LM, Furberg CD, DeMets DL . Sample size. In: Fundamentals of clinical trials.4th ed[M]. New York: Springer, 2010,: 133-162
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