Ginger,Pain,Primary dysmenorrhea,Stretching exercise," /> Ginger,Pain,Primary dysmenorrhea,Stretching exercise,"/> Use of ginger versus stretching exercises for the treatment of primary dysmenorrhea: A randomized controlled trial
Search JIM Advanced Search

Journal of Integrative Medicine ›› 2017, Vol. 15 ›› Issue (4): 295-301.doi: 10.1016/S2095-4964(17)60348-0

Special Issue: Natural Drug

• Research Article • Previous Articles     Next Articles

Use of ginger versus stretching exercises for the treatment of primary dysmenorrhea: A randomized controlled trial

Marjan Ahmad Shirvania, Narges Motahari-Tabaria, Abbas Alipourb   

  1. a Department of Midwifery, School of Nursing & Midwifery, Mazandaran University of Medical Sciences, Sari 4816715793, Iran 
    b Department of Community Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari 4847191971, Iran
  • Received:2017-01-12 Accepted:2017-03-31 Online:2017-07-15 Published:2017-07-15
  • Contact: Narges Motahari-Tabari; E-mail: narges_mth@yahoo.com

Background

Dysmenorrhea is a common gynecologic problem. In some cases, non-medical treatments are considered to be more effective, with fewer side effects. Ginger and exercise are alternative treatments for dysmenorrhea, but in the present study they were not combined.

Objective

In this study, the effects of ginger and exercise on primary dysmenorrhea were compared.

Design, Setting, Participants and Interventions

This randomized controlled trial was performed in Mazandaran University of Medical Sciences, Iran. Two groups of female students were recruited by simple random allocation. In each group, 61 students with moderate to severe primary dysmenorrhea with regular menstrual cycles and without a history of regular exercise were assessed. The ginger group received 250 mg ginger capsules from the onset of menstruation. In the exercise group, belly and pelvic stretching exercises were performed for 10 min, 3 times per week.

Main Outcome Measures

Intensity of pain was assessed according to a visual analogue scale after the first and the second month.

Results

Exercise was significantly more effective than ginger for pain relief (31.57 ± 16.03 vs 38.19 ± 20.47, P = 0.02), severity of dysmenorrhea (63.9% vs 44.3% mild dysmenorrhea, P = 0.02) and decrease in menstrual duration (6.08 ± 1.22 vs 6.67 ± 1.24, P = 0.006), in the second cycle.

Conclusion

Stretching exercises, as a safe and low-cost treatment, are more effective than ginger for pain relief in primary dysmenorrhea.

Trial registration

The trial was registered in www.IRCT.ir with No. 201203118822N2.

Key words: Ginger, Pain, Primary dysmenorrhea, Stretching exercise

CLC Number: 

  • We thank the vice-Chancellor for Research of Mazandaran University of Medical Sciences for supporting this project (grant number: H-92-24).
1 Dawood MY.Primary dysmenorrhea: advances in pathogenesis and management.Obstet Gynecol. 2006; 108(2): 428-441.
2 Lefebvre G, Pinsonneault O, Antao V, Black A, Burnett M, Feldman K, Lea R, Robert M; SOGC. Primary dysmenorrhea consensus guideline. J Obstet Gynaecol Can.2005; 27(12): 1117-1146. English and French.
3 Marjoribanks J, Proctor M, Farquhar C, Derks RS. Nonsteroidal anti-inflammatory drugs for dysmenorrhoea. Cochrane Database Syst Rev.2010; (1): CD001751.
4 Abdul-Razzak KK, Ayoub NM, Abu-Taleb AA, Obeidat BA.Influence of dietary intake of dairy products on dysmenorrhea.J Obstet Gynaecol Res. 2010; 36(2): 377-383.
5 5 Banikarim C, Middleman AB, Geffner M, Hoppin AG. Primary dysmenorrhea in adolescents. (2015-11-10) [2017- 01-16]. https://www.uptodate.com/contents/primarydysmenorrhea- in-adolescents.
6 Brown J, Brown S. Exercise for dysmenorrhoea. Cochrane Database Syst Rev.2010; (2): CD004142.
7 Collins Sharp BA, Taylor DL, Thomas KK, Killeen MB, Dawood MY.Cyclic perimenstrual pain and discomfort: the scientific basis for practice.J Obstet Gynecol Neonat Nurs. 2002; 31(6): 637-649.
8 Tavallaee M, Joffres MR, Corber SJ, Bayanzadeh M, Rad MM.The prevalence of menstrual pain and associated risk factors among Iranian women.J Obstet Gynaecol Res. 2011; 37(5): 442-451.
9 Gupta R, Kaur S, Singh A.Comparison to assess the effectiveness of active exercises and dietary gingervs. active exercises on primary dysmenorrhea among adolescent girls. Nurs Midwifery Res J. 2013; 9(4): 153.
10 Proctor ML, Murphy PA. Herbal and dietary therapies for primary and secondary dysmenorrhoea. Cochrane Database Syst Rev.2001; (3): CD002124.
11 Jenabi E.The effect of ginger for relieving of primary dysmenorrhoea.J Pak Med Assoc. 2013; 63(1): 8-10.
12 Rahnama P, Montazeri A, Huseini HF, Kianbakht S, Naseri M.Effect ofZingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC Complement Altern Med. 2012; 12(1): 92.
13 Terry R, Posadzki P, Watson LK, Ernst E.The use of ginger (Zingiber officinale) for the treatment of pain: a systematic review of clinical trials. Pain Med. 2011; 12(12): 1808-1818.
14 Blumenthal M, Busse W, Goldberg A.The complete German Commission E monographs: therapeutic guide to herbal medicines. Austin: American Botanical Council. 1998: 683.
15 Ozgoli G, Goli M, Moattar F.Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea.J Alternat Complement Med. 2009; 15(2): 129-132.
16 Shahr-jerdy S, Hosseini RS, Gh ME. Effects of stretching exercises on primary dysmenorrhea in adolescent girls.Biomed Human Kinetics. 2012; 4: 127-132.
17 Abbaspour Z, Rostami M, Najjar S.The effect of exercise on primary dysmenorrhea.J Res Health Sci. 2006; 6(1): 26-31.
18 Blakey H, Chisholm C, Dear F, Harris B, Hartwell R, Daley AJ, Jolly K.Is exercise associated with primary dysmenorrhoea in young women?BJOG. 2010; 117(2): 222-224.
19 Higuchi K, Umegaki E, Watanabe T, Yoda Y, Morita E, Murano M, Tokioka S, Arakawa T.Present status and strategy of NSAIDs-induced small bowel injury.J Gastroenterol. 2009; 44(9): 879-888.
20 Shi S, Klotz U.Clinical use and pharmacological properties of selective COX-2 inhibitors.Eur J Clin Pharmacol. 2008; 64(3): 233-252.
21 Altman R, Marcussen K.Effects of a ginger extract on knee pain in patients with osteoarthritis.Arthritis Rheum. 2001; 44(11): 2531-2238.
22 Mills S, Bone K.Principles and practice of phytotherapy: modern herbal medicine. London: Churchill Livingstone. 2000.
23 Halder A.Effect of progressive muscle relaxation versus intake of ginger powder on dysmenorrhoea amongst the nursing students in Pune.Nur J India. 2011; 103(4): 152-156.
24 Kashefi F, Khajehei M, Tabatabaeichehr M, Alavinia M, Asili J.Comparison of the effect of ginger and zinc sulfate on primary dysmenorrhea: a placebo-controlled randomized trial.Pain Manag Nurs. 2014; 15(4): 826-833.
25 Daley A.The role of exercise in the treatment of menstrual disorders: the evidence.Br J Gen Pract. 2009; 59(561): 241-242.
26 Chaudhuri A, Singh A, Dhaliwal L.A randomised controlled trial of exercise and hot water bottle in the management of dysmenorrhoea in school girls of Chandigarh, India.Indian J Physiol Pharmacol. 2013; 57(2): 114-122.
27 Rezvani S, Taghian F, Valiani M.The effect of aquatic exercises on primary dysmenorrhoea in nonathlete girls.Iran J Nurs Midwifery Res. 2013; 18(5): 378-383.
28 Izzo A, Labriola D.Dysmenorrhoea and sports activities in adolescents.Clin Exp Obstet Gynecol. 1991; 18(2): 109-116.
29 Maruf FA, Ezenwafor NV, Moroof SO, Adeniyi AF, Okoye EC.Physical activity level and adiposity: are they associated with primary dysmenorrhea in school adolescents?Afr J Reprod Health. 2013; 17(4): 167-174.
30 Mahvash N, Eidy A, Mehdi K, Zahra MT, Mani M, Shahla H.The effect of physical activity on primary dysmenorrhea of female university students.World Appl Sci J. 2012; 17(10): 1246-1252.
31 Shavandi M, Taghian F, Soltani V. The effect of isometric exercise on primary dysmenorrhea. Arak Med Univ J.2010; 13(1): 71-77. Persian.
32 Yang JJ, Sun LH, She YF, Ge JJ, Li XH, Zhang RJ. Influence of ginger-partitioned moxibustion on serum NO and plasma endothelin-1 contents in patients with primary dysmenorrhea of cold-damp stagnation type. Zhen Ci Yan Jiu.2008; 33(6): 409-412. Chinese with abstract in English.
33 Backon J.Mechanism of analgesic effect of clonidine in the treatment of dysmenorrhea.Med Hypotheses. 1991; 36(3): 223-224.
34 Alonso C, Coe CL.Disruptions of social relationships accentuate the association between emotional distress and menstrual pain in young women.Health Psychol. 2001; 20(6): 411-416.
35 Golomb LM, Solidum AA, Warren MP.Primary dysmenorrhea and physical activity.Med Sci Sports Exerc. 1998; 30(6): 906-909.
36 Wang L, Wang X, Wang W, Chen C, Ronnennberg A, Guang W, Huang A, Fang Z, Zang T, Wang L, Xu X.Stress and dysmenorrhoea: a population based prospective study.Occup Environ Med. 2004; 61(12): 1021-1026.
37 Gannon L.The potential role of exercise in the alleviation of menstrual disorders and menopausal symptoms: a theoretical synthesis of recent research.Women Health. 1988; 14(2): 105-127.
38 Locke RJ, Warren MP.Curbside Consult: what is the effect of exercise on primary dysmenorrhea?West J Med. 1999; 171(4): 264-265.
39 Metheny WP, Smith RP.The relationship among exercise, stress, and primary dysmenorrhea.J Behav Med. 1989; 12(6): 569-586.
[1] Chiung-Hui Huang, Mei-Ling Yeh, Fang-Pey Chen, Daphne Wu. Low-level laser acupuncture reduces postoperative pain and morphine consumption in older patients with total knee arthroplasty: A randomized placebo-controlled trial. Journal of Integrative Medicine, 2022, 20(4): 321-328.
[2] Xin Wang, Wen-juan Song, Yi Ruan, Bing-chu Li, Can Lü, Nian Huang, Fan-fu Fang, Wei Gu. Core muscle functional strength training for reducing the risk of low-back pain in military recruits: An open-label randomized controlled trial. Journal of Integrative Medicine, 2022, 20(2): 145-152.
[3] Zahra Karimzadeh, Mansooreh Azizzadeh Forouzi, Haleh Tajadini, Mehdi Ahmadinejad, Callista Roy, Mahlagha Dehghan. Effects of lavender and Citrus aurantium on pain of conscious intensive care unit patients: A parallel randomized placebo-controlled trial. Journal of Integrative Medicine, 2021, 19(4): 333-339.
[4] Thomas Efferth, An-long Xu, Roxana Damiescu, Mita Banerjee, Norbert W. Paul, David Y.W. Lee. Can eastern wisdom resolve western epidemics? Traditional chinese medicine therapies and the opioid crisis. Journal of Integrative Medicine, 2021, 19(4): 295-299.
[5] Xian Wang, Xuan Yin, Xiu-tian Guo, Yan Wang, Wen-qi Jin, Ai-jun Mao, Lixing Lao, Zhang-jin Zhang, Jie Zhang, Shi-fen Xu. Effects of the pestle needle therapy, a type of acupoint stimulation, on post-hemorrhoidectomy pain: A randomized controlled trial. Journal of Integrative Medicine, 2020, 18(6): 492-498.
[6] Johannes Loeser, Brigitte Layer, Christopher Plata, Klaus-Maria Perrar, Tim Hucho, Rebecca Kulbida. Hirudotherapy attenuates arthritic pain in patients with various chronic pain syndromes: A retrospective analysis. Journal of Integrative Medicine, 2020, 18(5): 425-433.
[7] . External application of two unrestricted herbal medicines to treat costochondritis in a young collegiate athlete: A case report. Journal of Integrative Medicine, 2020, 18(5): 450-454.
[8] Luciana Aikawa, Alexandre Massao Yoshizumi, Mirian Matsura Shirassu, Marcia Kiyomi Koike. Rapid acupuncture for musculoskeletal pain in the emergency room of the Hospital Servidor Publico Estadual, Brazil: A quasi-experimental study. Journal of Integrative Medicine, 2020, 18(4): 313-318.
[9] Rebecca Kulbida, Alexander Mathes, Johannes Loeser. Beneficial effects of hirudotherapy in a chronic case of complex regional pain syndrome. Journal of Integrative Medicine, 2019, 17(5): 383-386.
[10] Stefania Lamponi, Anna Maria Aloisi, Claudia Bonechi, Marco Consumi, Alessandro Donati, Gemma Leone, Claudio Rossi, Gabriella Tamasi, Luana Ghiandai, Ersilia Ferrini, Paolo Fiorenzani, Ilaria Ceccarelli, Agnese Magnani. Evaluation of in vitro cell and blood compatibility and in vivo analgesic activity of plant-derived dietary supplements. Journal of Integrative Medicine, 2019, 17(3): 213-220.
[11] Arthur Yin Fan, Hui Ouyang, Xinru Qian, Hui Wei, David Dehui Wang, Deguang He, Haihe Tian, Changzhen Gong, Amy Matecki, Sarah Faggert Alemi. Discussions on real-world acupuncture treatments for chronic low-back pain in older adults. Journal of Integrative Medicine, 2019, 17(2): 71-76.
[12] Michelle T. Jesse, Mathew Kulas, Josephine Unitis, Nemie Beltran, Marwan Abouljoud. Acupuncture in living liver and kidney donors: a feasibility study. Journal of Integrative Medicine, 2019, 17(1): 3-7.
[13] Ralph Fernando Rosas, Aline Armiliato Emer, Ana Paula Batisti, Daniela Dero Ludtke, Bruna Lenfers Turnes, Franciane Bobinski, Francisco José Cidral-Filho, Daniel Fernandes Martins. Far infrared-emitting ceramics decrease Freund’s adjuvant-induced inflammatory hyperalgesia in mice through cytokine modulation and activation of peripheral inhibitory neuroreceptors. Journal of Integrative Medicine, 2018, 16(6): 396-403.
[14] Ching-Feng Su. Home care with acupuncture increased the quality of life in a patient with advanced cancer with neuropathic pain induced by bone metastasis: A case report. Journal of Integrative Medicine, 2018, 16(3): 208-210.
[15] Sepideh Hamdamian, Soheila Nazarpour, Masoumeh Simbar, Sepideh Hajian, Faraz Mojab, AtefehTalebi. Effects of aromatherapy with Rosa damascena on nulliparous women’s pain and anxiety of labor during first stage of labor. Journal of Integrative Medicine, 2018, 16(2): 120-125.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Fu-rong Du , Bin Zhang. Study on English translation for rhetoric devices in Neijing; intertextuality and synecdoche. Journal of Chinese Integrative Medicine, 2010, 8(12): 1207-1210
[2] Mei-jun Lü, Hui-yong Zhang, Zhe Zhang, Guan-lin Yang. Measurement of health-related quality of life in coronary heart disease: A review. Journal of Chinese Integrative Medicine, 2011, 9(12): 1277-1285
[3] Hua-fa Que, Han-jun Tang, Lin-yang Wang, Hong-yu Dai, Shi-yun Zhang, Hai-guang Qin, Xiao-dong Liu, Huan-yu Xiang, Zhen Zhang. Study on wound healing mechanism of replenishing qi and dissipating stagnation therapy for chronic skin ulcers. Journal of Chinese Integrative Medicine, 2005, 3(3): 243-246
[4] Wen-hui Ma, Xiao-hong Sun. Discussion of time and space differentiation of three-yin and three-yang in Shanghan Lun. Journal of Chinese Integrative Medicine, 2005, 3(4): 257-259
[5] Dong Yang, Shi Jian-rong. Biological research evaluating the Chinese medical theory of the association of the kidney with the ears. Journal of Chinese Integrative Medicine, 2012, 10(2): 128-134
[6] Xiao-hui Sun, Sheng Liu . External Chinese medical therapy for pain associated with hyperplastic disease of the breast: Study protocol of a randomized, double-blind, multicenter, controlled trial. Journal of Chinese Integrative Medicine, 2012, 10(4): 384-389
[7] Hai-bo Yu, Cheng-en Pan, Wu-jun Wu, Si-hai Zhao, Hui-feng Zhang. Effects of resveratrol on matrix metalloproteinase-9 expression in hepatoma cells. Journal of Chinese Integrative Medicine, 2008, 6(3): 270-273
[8] Xiao-long Wei, Rui Feng, Zhi-qing Zhao, Zai-ping Jing. Efficacy of Chinese herbal medicine Mailuo Shutong Granule and Hirudoid cream for chronic venous disorder-induced pigmentation in lower extremities: A prospective, randomized controlled trial. Journal of Chinese Integrative Medicine, 2011, 9(8): 866-870
[9] Hui Han , Li-min Wu , Ming-xiang Han, Wen-ming Yang , Dao-jun Xie , Zhao-hui Fang , Dan-chen Chu , Fang Fang . Effects of Chinese herbal medicine Shenxiong Yujing Granule on regeneration of neural cells in rats with diabetes-associated cerebral ischemia. Journal of Chinese Integrative Medicine, 2012, 10(10): 1140-1148
[10] ZG Li. Comparative study on WHO Western Pacific Region and World Federation of Chinese Medicine Societies international standard terminologies on traditional medicine: An analysis of the Causes of Diseases (Part 2). Journal of Chinese Integrative Medicine, 2009, 7(4): 383-388