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Journal of Chinese Integrative Medicine ›› 2008, Vol. 6 ›› Issue (8): 867-872.doi: 10.3736/jcim20080819

• Literature Review • Previous Articles     Next Articles

Research of traditional Chinese medicine in the treatment of leukemia: current status

Ya-lin Fu(), Tao Chen   

  1. Department of Traditional Chinese Medicine, Three Gorges University Medical College, Yichang, Hubei Province 443002, China
  • Received:2008-01-29 Online:2008-08-20 Published:2008-08-15

Key words: Chinese herbal drugs, effective components, leukemia

CLC Number: 

  • R733.7
[1] Huang YQ . Chinese medicine is not "reserve" on the treatment of leukemia[J]. Jia Ting Zhong Yi Yao, 2006,13(10):24-25
黄衍强 . 治疗白血病中药不是“备役”[J]. 家庭中医药, 2006,13(10):24-25
[2] Wang DS, Liu BZ . T.he molecular mechanism of anti-leukenia Chinese medicine and its active ingredients[J]. Guo Ji Zhong Yi Zhong Yao Za Zhi, 2007,29(3):160-163
doi: 10.3760/cma.j.issn.1673-4246.2007.03.010
王东生, 刘北忠 . 中药及其有效成分抗白血病的分子机制[J]. 国际中医中药杂志, 2007,29(3):160-163
doi: 10.3760/cma.j.issn.1673-4246.2007.03.010
[3] Li T, Ma MF . Experience of Chinese medicine in the application of hematopoietic stem cell transplantation in treatment of acute leukemia[J]. Zhongguo Yi Yao Xue Bao, 2002,17(2):101-104
李仝, 马鸣飞 . 中医药在造血干细胞移植治疗急性白血病中的应用体会[J]. 中国医药学报, 2002,17(2):101-104
[4] Tang YJ . Study on the treatment of leukemia by anticancer traditional proprietary Chinese medicine combined with Chinese herbal compound[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 1998,18(10):583-584
doi: 10.7661/CJIM.1998.10.583
唐由君 . 传统抗癌中成药配合中药复方治疗白血病的研究[J]. 中国中西医结合杂志, 1998,18(10):583-584
doi: 10.7661/CJIM.1998.10.583
[5] Liu J, Wang HX, Wang SQ , et al. Tablets of composite natural indigo in the treatment of refractory or relapsed acute promyelocytic leukemia[J]. Shandong Yi Yao, 2007,47(20):32-33
doi: 10.3969/j.issn.1002-266X.2007.20.014
刘捷, 王海霞, 王树庆 , 等. 复方青黛片治疗难治性、复发性急性早幼粒细胞白血病[J]. 山东医药, 2007,47(20):32-33
doi: 10.3969/j.issn.1002-266X.2007.20.014
[6] Bi LL, Ma Q, Wang SQ , et al. Treatment of 32 cases with recurring acute promyelocytic leukemia with tablets of composite natural indigo[J]. Zhonghua Er Ke Za Zhi, 2005,43(9):702-703
doi: 10.3760/j.issn:0578-1310.2005.09.020
毕玲玲, 马琴, 王树庆 , 等. 复方青黛片治疗复发性急性早幼粒细胞白血病32例[J]. 中华儿科杂志, 2005,43(9):702-703
doi: 10.3760/j.issn:0578-1310.2005.09.020
[7] Du ZL, Wang R, Chen H . Recent development of traditional Chinese medicine therapy to leukemia[J]. Di Yi Jun Yi Da Xue Fen Xiao Xue Bao, 2005,28(1):97-100
杜振兰, 王瑞, 陈虎 . 中医药治疗白血病的现状[J]. 第一军医大学分校学报, 2005,28(1):97-100
[8] Wang ZM, Yang GH, Yao FL . Treatment of acute leukemia with traditional Chinese medicine[J]. Zhongguo Zi Ran Yi Xue Za Zhi Yi Xue Za Zhi., 2000,2(1):26-28
王泽民, 杨国华, 姚奉理 . 鲜中药治疗急性白血病76例[J]. 中国自然医学杂志, 2000,2(1):26-28
[9] Fan XJ, Li J, Wang ZX . Wang san-hu's experience in the treatment of leukemia[J]. Guangxi Zhong Yi Yao, 2007,30(5):42-43
范先基, 李俊, 王志祥 . 王三虎治疗白血病的经验[J]. 广西中医药, 2007,30(5):42-43
[10] Deng YA, Yang CM, Xie B . Clinical observation of Huoxue Huayu herbal medicine combined with chemotherapy in treating 20 cases of acute leukemia[J]. Zhongguo Yi Yao Ke Ji, 2000,7(2):110-111
邓有安, 杨才明, 谢波 . 活血化瘀中药联合化疗治疗急性白血病20例临床观察[J]. 中国医药科技, 2000,7(2):110-111
[11] Liu JJ, Pan XL, Wu XY , et al. Inhibitory effect and mechanism of oridonin on Raji cells proliferation[J]. Zhong Cao Yao, 2004,35(7):774-777
刘加军, 潘祥林, 伍新尧 , 等. 冬凌草甲素对Raji细胞的增殖抑制作用及其机制[J]. 中草药, 2004,35(7):774-777
[12] Zhao XY, Xu L, Zhang XH , et al. Effect of taxol on proliferation and apoptosis of human leukemia cell line K562 in vitro[J]. Shi Yong Zhong Liu Za Zhi, 2002,17(6):376-378
doi: 10.3969/j.issn.1001-1692.2002.06.006
赵小英, 徐磊, 张晓红 , 等. 紫杉醇对K562细胞增殖抑制及诱导凋亡的作用[J]. 实用肿瘤杂志, 2002,17(6):376-378
doi: 10.3969/j.issn.1001-1692.2002.06.006
[13] Sun ZX, Zhang YH, Cheng S , et al. Anti-tumor effect of ethanol extracts from Thymus quinquecostatus Celak on human leukemia cell line[J]. Zhong Xi Yi Jie He Xue Bao, 2005,3(5):382-385
孙震晓, 张英慧, 程霜 , 等. 中药地椒乙醇提取物对人白血病细胞增殖的抑制作用[J]. 中西医结合学报, 2005,3(5):382-385
[14] Wang XG, Chen GY, Fang Q . Effect of allicin on telomerase of HL-60 cell[J]. Guizhou Yi Yao, 2004,28(4):303-305
王旭光, 陈根殷, 方琦 . 大蒜素对HL-60细胞端粒酶活性的影响[J]. 贵州医药, 2004,28(4):303-305
[15] Yan C, Jamaluddin MS, Aggarwal B , et al. Gene expression profiling identifies activating transcription factor 3 as a novel contributor to the proapoptotic effect of curcumin[J]. Mol Cancer Ther, 2005,4(2):233-241
doi: 10.4161/cbt.4.2.1475 pmid: 15655351
[16] Thomas RK, Sos ML, Zander T , et al. Inhibition of nuclear translocation of nuclear factor-kappaB despite lack of functional IkappaBalpha protein overcomes multiple defects in apoptosis signaling in human B-cell malignancies[J]. Clin Cancer Res, 2005,11(22):8186-8194
doi: 10.1158/1078-0432.CCR-05-0224
[17] Wang GJ, Zhou LM, Wang L , et al. Study on apoptosis of human leukemia HL-60 cells induced by Sanchinoside R1[J]. Sichuan Sheng Li Ke Xue Za Zhi, 2004,26(1):14-16
doi: 10.3969/j.issn.1671-3885.2004.01.005
王国俊, 周黎明, 王莉 , 等. 三七皂甙R1诱导HL-60细胞凋亡的初步研究[J]. 四川生理科学杂志, 2004,26(1):14-16
doi: 10.3969/j.issn.1671-3885.2004.01.005
[18] Zhang TC, Schmitt MT, Mumford JL . Effects of arsenic on telomerase and telomeres in relation to cell proliferation and apoptosis in human keratinocytes and leukemia cells in vitro[J]. Carcinogenesis, 2003,24(11):1811-1817
doi: 10.1093/carcin/bgg141
[19] Hua BJ . Study on the mechanism of differentiation and apoptosis of tumor cells induced by effective monomers of Chinese medicina herbs[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 2002,8(7):63-65
doi: 10.3969/j.issn.1006-3250.2002.07.031
花宝金 . 中药有效单体对肿瘤细胞诱导分化及凋亡的机制研究[J]. 中国中医基础医学杂志, 2002,8(7):63-65
doi: 10.3969/j.issn.1006-3250.2002.07.031
[20] Yuan D, Zuo R, Zhang CC . Effects of total saponins of Panax japonicus on human leukemic HL-60 cells[J]. Zhong Xi Yi Jie He Xue Bao, 2007,5(5):570-572
袁丁, 左锐, 张长城 . 竹节参总皂苷对人白血病细胞株HL-60的作用[J]. 中西医结合学报, 2007,5(5):570-572
[21] Sun J, Li Z, Jian LL . Study on Chinese hebal medicine induced leukemic cell apoptosis[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2001,21(11):875-877
doi: 10.7661/CJIM.2001.11.875
孙静, 李震, 简隆磊 . 中药诱导白血病细胞凋亡的研究[J]. 中国中西医结合杂志, 2001,21(11):875-877
doi: 10.7661/CJIM.2001.11.875
[22] Chen GQ, Shi XG, Tang W , et al. Use of arsenic trioxide(As2O3) in the treatment of acute promyelocytic leukemia(APL): I. As2O3 exerts dose-dependent dual effects on APL cells[J]. Blood, 1997,89(9):3345-3353
doi: 10.1007/BF02781736 pmid: 10703942
[23] Zhang Y, Schlussman SD, Ho A , et al. Effect of acute binge cocaine on levels of extracellular dopamine in the caudate putamen and nucleus accumbens in male C57BL/6J and 129/J mice[J]. Brain Res, 2001,923(1-2):172-177
doi: 10.1016/S0006-8993(01)03032-3
[24] Danilenko M, Wang Q, Wang X , et al. Carnosic acid potentiates the antioxidant and prodifferentiation effects of 1alpha, 25-dihydroxyvitamin D3 in leukemia cells but does not promote elevation of basal levels of intracellular calcium[J]. Cancer Res, 2003,63(6):1325-1332
[25] Li XH . Advance in treatment of leukocythemia with traditional Chinese medicine[J]. Yao Xue Jin Zhan, 2001,25(5):284-288
李晓惠 . 中药治疗白血病的研究进展[J]. 药学进展, 2001,25(5):284-288
[26] Zhang C, Huang SL, Xiang Y , et al. Study on Realgar inducing apoptosis in T lymphocytic cell line CEM[J]. Zhong Xi Yi Jie He Xue Bao, 2003,1(1):42-43
张晨, 黄世林, 向阳 , 等. 雄黄对T淋巴细胞白血病细胞系CEM的促凋亡作用[J]. 中西医结合学报, 2003,1(1):42-43
[27] Suzuki K, Adachi R, Hirayama A , et al. Indirubin, a Chinese anti-leukaemia drug, promotes neutrophilic differentiation of human myelocytic leukaemia HL-60 cells[J]. Br J Haematol, 2005,130(5):681-690
doi: 10.1111/bjh.2005.130.issue-5
[28] Dai YC, Mao XZ . Significance of apoptosis in tumorgenesis and treatment[J]. Zhong Liu, 1995,15(3):279-282
戴育成, 毛享贞 . 细胞凋亡在肿瘤发生和治疗上的意义[J]. 肿瘤, 1995,15(3):279-282
[29] Huang HY, Yu EX . Effects of traditional Chinese medicine on the NK, LAK cells and activity of IL-2[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 1993,13(4):253-255
黄海茵, 于尔辛 . 中药对NK、LAK细胞及IL-2活性的影响[J]. 中国中西医结合杂志, 1993,13(4):253-255
[30] Gao N, Mao JQ, Zhang Y . Research progress of traditional Chinese medicine on reversing multidrug resistance of leukemia[J]. Jiangsu Zhong Yi Yao, 2007,39(3):60-62
doi: 10.3969/j.issn.1672-397X.2007.03.035
高娜, 茆俊卿, 张育 . 中药逆转白血病多药耐药的研究进展[J]. 江苏中医药, 2007,39(3):60-62
doi: 10.3969/j.issn.1672-397X.2007.03.035
[31] Liang H, Zhang Y, Zhang JD , et al. Effects of arsenic trioxide on expressions of vascular endothelial growth factor and P-glycoprotein in multidrug resistant leukemia cell line K562/A02[J]. Zhong Xi Yi Jie He Xue Bao, 2007,5(6):647-650
梁虹, 张育, 张建东 , 等. 三氧化二砷对耐药白血病细胞血管内皮生长因子和P-糖蛋白表达的影响[J]. 中西医结合学报, 2007,5(6):647-650
[32] Li DY, Chen XY, Xu YM . The progress and the present of patients with refractory acute leukemia[J]. Xian Dai Sheng Wu Yi Xue Jin Zhan, 2007,7(8):1239-1245
doi: 10.3969/j.issn.1673-6273.2007.08.044
李冬云, 陈信义, 许亚梅 . 难治性急性白血病研究现状与进展[J]. 现代生物医学进展, 2007,7(8):1239-1245
doi: 10.3969/j.issn.1673-6273.2007.08.044
[33] Jiang JB, He JH, Wu HT , et al. Clinical observation of Shenmai Injection in treatment of toxic and adverse reactions of anthracycline chemotherapy in leukemia[J]. Xin Zhong Yi, 2000,32(5):19-20
doi: 10.3969/j.issn.0256-7415.2000.05.010
江劲波, 何俊辉, 吴华堂 , 等. 参麦注射液对白血病蒽环类药物化疗减毒作用的临床观察[J]. 新中医, 2000,32(5):19-20
doi: 10.3969/j.issn.0256-7415.2000.05.010
[34] Li F, Wu SL, Kong CF . Application of Shenmai Injection in the chemotherapy of acute leukemia[J]. Jiangxi Yi Xue Yuan Xue Bao, 2002,42(1):48
doi: 10.3969/j.issn.1000-2294.2002.01.058
李菲, 伍世礼, 孔床芬 . 参麦注射液在急性白血病化疗时的应用[J]. 江西医学院学报, 2002,42(1):48
doi: 10.3969/j.issn.1000-2294.2002.01.058
[35] Ma WK, Zhang HC . Discussion of preventing and treating side effect of chemotherapy in acute leukemia with compound recipe[J]. Jiangxi Zhong Yi Yao, 2007,38(1):42-43
doi: 10.3969/j.issn.0411-9584.2007.01.022
马武开, 张惠臣 . 中药复方防治急性白血病化疗毒副作用探讨[J]. 江西中医药, 2007,38(1):42-43
doi: 10.3969/j.issn.0411-9584.2007.01.022
[36] Ma WK . Ideas and methods of Chinese medicine in the prevention and treatment of leukemia[J]. Zhongguo Zhong Yi Yao Xin Xi Za Zhi, 2004,11(3):229-230
doi: 10.3969/j.issn.1005-5304.2004.03.022
马武开 . 中医药防治白血病的思路及方法[J]. 中国中医药信息杂志, 2004,11(3):229-230
doi: 10.3969/j.issn.1005-5304.2004.03.022
[37] Zhao TH, Su JQ . Positive regulation of Shengmaisan plus Astragali on anti-tumor activity of LAK cells[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 1993,13(8):471-472
赵铁华, 粟锦迁 . 生脉散加黄芪对LAK细胞抗肿瘤活性的正向调节作用[J]. 中国中西医结合杂志, 1993,13(8):471-472
[38] Xie XS . Natural medicines and modern treatment of leukemia[J]. Yi Xue Zong Shu, 1999,5(12):F003-F004
谢新生 . 天然药物与白血病的现代治疗[J]. 医学综述, 1999,5(12):F003-F004
[39] Li O, Tian WW, Deng DC . Influence of "Bu-sheng-yi-qi" granule to natural killer cell and activity of interleukin-2 of P388 leukemia mice after treating by chemistry therapy[J]. Chengdu Zhong Yi Yao Da Xue Xue Bao, 2001,24(1):40-41
doi: 10.3969/j.issn.1004-0668.2001.01.020
李偶, 田卫卫, 邓道昌 . 补肾益气冲剂对P388白血病小鼠化疗后自然杀伤细胞、白介素-2活性的影响[J]. 成都中医药大学学报, 2001,24(1):40-41
doi: 10.3969/j.issn.1004-0668.2001.01.020
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