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Journal of Chinese Integrative Medicine ›› 2009, Vol. 7 ›› Issue (6): 575-581.doi: 10.3736/jcim20090615

Special Issue: Acupuncture & Moxibustion

• Literature Review • Previous Articles     Next Articles

Research on receptors related to acupuncture analgesia and positron emission tomography radioligands: A review

Wang Hui-chun, Zuo Chuan-tao, Guan Yi-hui   

  1. PET Center, Huashan Hospital, Fudan University, Shanghai 200235, China
  • Received:2008-12-11 Accepted:2009-02-22 Online:2009-06-20 Published:2009-06-15

Key words: Acupuncture analgesia, Electro-acupuncture, Receptor, Positron emission tomography, Radioligand

"

Receptors Effects in AA by activating receptors Radioligands with 11C
OR 11C-DPN
μ/δ Mediate low frequency EA (physiological pain) 11C-CFN/11C-MeNTI
Mediate EA (pathological pain)
κ Mediate high frequency EA (physiological pain) 11C-GR103545, 11C-GR89696
Inaction (pathological pain) 11C-MeJDTic
OFQR Diversity
5-HT1A/5-HT3 Synergism 11C-WAY100635, 11C-DWAY
11C-CPC-222, 11C-(R)-RWAY
11C-CUMI-101
5-HT2 Antagonism 11C-MDL100907
GABAA Synergism (spinal cord) 11C-flumazenil, 11C-PK11195
11C-DAA1106, 11C-Ro151788
GABAB Synergism 11C-CGP62349
α1 Antagonism (brain) 11C-GB67
α2 Synergism (spinal cord)
D1 Antagonism (brain) 11C-SCH2399086, 11C-NNC112
D2 Synergism (spinal cord) 11C-raclopride, 11C-FLB457
11C-N-propylnoraporphin
11C-(+)PHNO
M Synergism 11C-4-NMPB, 11C-3-NMPB
11C-bezotropine
NMDA Antagonism
AMPA/KA Antagonism
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