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Journal of Chinese Integrative Medicine ›› 2011, Vol. 9 ›› Issue (9): 955-964.doi: 10.3736/jcim20110906

Special Issue: Traditional Chinese Medicine

• Original Clinical Research • Previous Articles     Next Articles

Traditional Chinese medicine syndrome factors of patients with HIV infection or AIDS in China

Feng Jiang1(), Lin-chun Fu2, Jian-ping Ma3, Qing Zhou4, Bo Peng5, Shi-ping Xie5, Hui-jun Guo1, Yong-xin Dong2, Xiu-lan Ma3, Xuan-xian Guo5, Zhong-li Xie5, Yan-ping Hu5, Qing-ya Li5, Hua-wei Li5, Yan-tao Jin1   

  1. 1. AIDS Clinical Center, No. 1 Hospital, Henan University of Traditional Chinese Medicine, Zhengzhou 450000, Henan Province, China
    2. Institute of Tropical Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, Guangdong Province, China
    3. Research Laboratory of AIDS, Academy of Traditional Chinese Medicine of Xinjiang Uygur Autonomous Region, Urumchi 830000, Xinjiang Uygur Autonomous Region, China
    4. Science and Technology Department, Yunan University of Traditional Chinese Medicine, Kunming 650200, Yunnan Province, China
    5. Institute of AIDS, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China
  • Received:2011-03-23 Accepted:2011-05-11 Online:2011-09-20 Published:2011-09-15
  • Contact: Jiang Feng E-mail:jiangfengdoc@sohu.com

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Objective: To study the characteristics of traditional Chinese medicine (TCM) syndrome factors of patients from different areas of China with human immunodeficiency virus (HIV) infection or acquired immunodeficiency syndrome (AIDS).

Methods: A cross-sectional investigation study was conducted in Henan, Guangdong and Yunnan Provinces and Xinjiang Uygur Autonomous Region of China from October 2008 to August 2010. Based on literature review and expert opinion, a clinical questionnaire of TCM syndromes was drawn up. This survey was carried out after the investigators were professionally trained. Wenfeng Ⅲ Auxiliary Diagnosis and Treat System of TCM was used to analyze the frequencies of AIDS patients’ signs and symptoms with scores above 70 of syndrome factors respectively. Based on this work, syndrome factors of AIDS were analyzed in different areas.

Results: There were 608 HIV/AIDS cases investigated from October 2008 to August 2010 in total; among them, 276 cases were from Henan, 126 cases from Guangdong, 120 cases from Xinjiang and 86 cases from Yunnan. The results of syndrome factor analysis indicated that the syndromes of four provinces were similar. HIV/AIDS patients in the four areas exhibited qi deficiency, blood deficiency, yin deficiency, yang deficiency, dampness, phlegm, qi stagnation and essence deficiency syndromes. Patients in each area also had their own characteristics, such as that the scores of dampness of Guangdong and yin deficiency of Xinjiang were higher than the other syndromes, whereas the scores of Henan Province were higher than the other areas. AIDS patients had higher scores of syndromes than HIV-infected patients.

Conclusion: HIV/AIDS patients from different areas had similar syndrome elements. The theory of “AIDS toxin injurying primordial qi” can sum up the TCM etiology and pathogenesis of HIV/AIDS.

Key words: AIDS, syndrome factors, etiology and pathogenesis, cross-section survey

Table 1

Characteristics of baseline of HIV-infected patients in four regions"

Group HIV-infected cases Age ($\overline{x}$±s, years)
Male Female
Hennan (n=101) 54 47 45.88±8.29
Guangdong (n=41) 22 19 38.85±10.34
Xinjiang (n=40) 24 16 37.68±6.53
Yunnan (n=26) 8 18 38.73±10.86

Table 2

Characteristics of baseline of AIDS patients in four regions"

Group AIDS cases Age ($\overline{x}$±s, years)
Male Female
Hennan (n=175) 106 69 45.94±8.57
Guangdong (n=85) 62 23 38.17±8.53
Xinjiang (n=80) 57 23 37.40±9.65
Yunnan (n=60) 36 24 39.72±10.81

Table 3

Scores of syndrome factors of HIV/AIDS patients in Henan Province ($\overline{x}$±s)"

Group n Qi-deficiency Yang-deficiency Yin-deficiency Blood-deficiency
HIV-infected
CD4+>350 cells/μL 51 74.31±78.25 36.47±52.63 70.82±71.84 59.22±70.96
CD4+<350 cells/μL 50 143.70±118.19 101.58±99.21 112.18±84.67 95.34±81.98
AIDS 175 203.39±91.96 165.22±86.34 134.37±75.24 128.98±74.61
P value Pin=0.002;
Pout1=0.001;
Pout2=0.001		 Pin=0.001;
Pout1=0.001;
Pout2=0.001		 Pin=0.009;
Pout1=0.001;
Pout2=0.075		 Pin=0.020;
Pout1=0.001;
Pout2=0.006
Group n Dampness Phlegm Essence-deficiency Qi-stagnation
HIV-infected
CD4+>350 cells/μL 51 64.31±76.51 66.08±64.35 22.35±39.41 6.18±27.74
CD4+<350 cells/μL 50 82.14±78.05 74.04±78.29 42.76±54.04 29.90±65.08
AIDS 175 128.58±70.29 99.75±76.17 54.17±50.52 46.17±57.51
P value Pin=0.249;
Pout1=0.001;
Pout2=0.001		 Pin=0.578;
Pout1=0.004;
Pout2=0.038		 Pin=0.040;
Pout1=0.001;
Pout2=0.167		 Pin=0.017;
Pout1=0.001;
Pout2=0.088

Table 4

Positive rate of syndrome factors of HIV/AIDS patients in Henan Province"

Group n Qi-deficiency Yang-deficiency Yin-deficiency Blood-deficiency
HIV-infected
CD4+>350 cells/μL 51 54.9% (28/51) 35.3% (18/51) 56.9% (29/51) 49.0% (25/51)
CD4+<350 cells/μL 50 72.0% (36/50) 60.0% (30/50) 61.2% (36/50) 64.0% (32/50)
AIDS 175 96.0% (168/175) 90.3% (158/175) 86.3% (151/175) 83.4% (146/175)
χ2 value 56.401 69.999 21.502 31.090
P value 0.001 0.001 0.001 0.001
Group n Dampness Phlegm Essence-deficiency Qi-stagnation
HIV-infected
CD4+>350 cells/μL 51 49.0% (25/51) 56.9% (29/51) 25.5% (13/51) 5.9% (3/51)
CD4+<350 cells/μL 50 58.0% (29/50) 54.0% (27/50) 42.0% (21/50) 21.6% (11/50)
AIDS 175 84.6% (148/175) 71.4% (125/175) 56.0% (98/175) 42.8% (75/175)
χ2 value 32.615 7.339 15.563 27.646
P value 0.001 0.025 0.001 0.001

Table 5

Scores of syndrome factors of HIV/AIDS patients in Guangdong Province ($\overline{x}$±s)"

Group n Qi-deficiency Dampness Blood-deficiency Yang-deficiency
HIV-infected
CD4+ >350 cells/μL 20 101.58±74.27 70.42±57.52 106.95±60.72 41.63±52.05
CD4+ <350 cells/μL 21 123.41±81.23 70.50±74.28 94.09±71.49 66.36±62.53
AIDS 85 166.86±72.67 130.59±58.13 125.99±81.22 114.91±77.23
P value Pin=0.378;
Pout1=0.001;
Pout2=0.016		 Pin=0.997;
Pout1=0.001;
Pout2=0.001		 Pin=0.542;
Pout1=0.338;
Pout2=0.096		 Pin=0.181;
Pout1=0.001;
Pout2=0.008
Group n Phlegm Yin-deficiency Qi-stagnation Essence-deficiency
HIV-infected
CD4+ >350 cells/μL 20 15.26±38.35 25.00±44.91 3.68±16.06 29.63±45.17
CD4+ <350 cells/μL 21 50.91±59.79 55.91±71.06 17.73±33.65 28.64±43.95
AIDS 85 91.10±75.68 78.22±72.20 32.21±53.67 16.34±35.15
P value Pin=0.035;
Pout1=0.001;
Pout2=0.023		 Pin=0.146;
Pout1=0.002;
Pout2=0.197		 Pin=0.106;
Pout1=0.024;
Pout2=0.336		 Pin=0.943;
Pout1=0.145;
Pout2=0.155

Table 6

Positive rate of syndrome factors of HIV/AIDS patients in Guangdong Province"

Group n Qi-deficiency Dampness Blood-deficiency Yang-deficiency
HIV-infected
CD4+>350 cells/μL 20 75.0% (15/20) 65.0% (13/20) 80.0% (16/20) 45.0% (9/20)
CD4+<350 cells/μL 21 85.7% (18/21) 57.1% (12/21) 71.4% (15/21) 61.9% (13/21)
AIDS 85 94.1% (80/85) 94.1% (80/85) 77.6% (66/85) 80.0% (68/85)
χ2 value 5.914 22.329 0.475 10.838
P value 0.052 0.001 0.789 0.004
Group n Phlegm Yin-deficiency Qi-stagnation Essence-deficiency
HIV-infected
CD4+>350 cells/μL 20 20.0% (4/20) 30.0% (6/20) 10.0% (2/20) 35.0% (7/20)
CD4+<350 cells/μL 21 42.8% (9/21) 42.8% (9/21) 23.8% (5/21) 28.6% (6/21)
AIDS 85 65.9% (56/85) 61.2% (52/85) 29.4% (25/85) 18.8% (16/85)
χ2 value 15.200 7.398 3.253 2.700
P value 0.001 0.025 0.197 0.259

Table 7

Scores of syndrome factors of HIV/AIDS patients in Xinjiang Uygur Autonomous Region ($\overline{x}$±s)"

Group n Qi-deficiency Yin-deficiency Blood-deficiency Dampness
HIV-infected
CD4+>350 cells/μL 20 63.25±64.99 52.35±64.75 47.00±74.14 39.55±62.95
CD4+<350 cells/μL 20 65.50±55.58 37.85±61.30 30.25±55.07 33.60±49.04
AIDS 80 147.28±56.41 124.06±82.43 97.26±69.43 89.73±70.63
P value Pin=0.907;
Pout1=0.001;
Pout2=0.001		 Pin=0.472;
Pout1=0.001;
Pout2=0.001		 Pin=0.410;
Pout1=0.005;
Pout2=0.001		 Pin=0.741;
Pout1=0.005;
Pout2=0.001
Group n Phlegm Yang-deficiency Qi-stagnation Essence-deficiency
HIV-infected
CD4+>350 cells/μL 20 36.25±47.15 24.00±60.82 5.00±22.36 4.75±21.24
CD4+<350 cells/μL 20 45.75±61.88 21.75±39.64 4.00±17.89 19.25±40.04
AIDS 80 59.94±70.99 44.15±63.58 28.25±48.31 40.81±50.75
P value Pin=0.588;
Pout1=0.216;
Pout2=0.415		 Pin=0.890;
Pout1=0.204;
Pout2=0.190		 Pin=0.877;
Pout1=0.036;
Pout2=0.031		 Pin=0.151;
Pout1=0.003;
Pout2=0.084

Table 8

Positive rate of syndrome factors of HIV/AIDS patients in Xinjiang Uygur Autonomous Region"

Group n Qi-deficiency Yin-deficiency Blood-deficiency Dampness
HIV-infected
CD4+>350 cells/μL 20 55.0% (11/20) 45.0% (9/20) 35.0% (7/20) 30.0% (6/20)
CD4+<350 cells/μL 20 65.0% (13/20) 30.0% (6/20) 25.0% (5/20) 35.0% (7/20)
AIDS 80 95.0% (76/80) 78.7% (63/80) 73.7% (59/80) 70.0% (56/80)
χ2 value 22.949 20.934 21.541 15.448
P value 0.001 0.001 0.001 0.001
Group n Phlegm Yang-deficiency Qi-stagnation Essence-deficiency
HIV-infected
CD4+>350 cells/μL 20 40.0% (8/20) 15.0% (3/20) 5.0% (1/20) 5.0% (1/20)
CD4+<350 cells/μL 20 40.0% (8/20) 25.0% (5/20) 5.0% (1/20) 20.0% (4/20)
AIDS 80 48.7% (39/80) 37.5% (30/80) 44.0% (22/80) 42.5% (34/80)
χ2 value 0.822 4.236 10.108 11.966
P value 0.663 0.120 0.006 0.003

Table 9

Scores of syndrome factors of HIV/AIDS patients in Yunnan Province ($\overline{x}$±s)"

In: compared in HIV-infected groups; Out: compared with AIDS (1: CD4+>350 cells/μL; 2: CD4+<350 cells/μL). HIV: human immunodeficiency virus; AIDS: acquired immunodeficiency syndrome.
Group n Qi-deficiency Yang-deficiency Blood-deficiency Yin-deficiency
HIV-infected
CD4+>350 cells/μL 13 34.77±66.27 18.08±44.13 35.38±58.96 20.00±38.13
CD4+<350 cells/μL 13 104.23±84.92 64.23±71.03 104.23±84.92 62.08±68.25
AIDS 60 126.44±98.79 89.44±94.10 86.95±92.99 82.88±81.67
P value Pin=0.029;
Pout1=0.390;
Pout2=0.002		 Pin=0.053;
Pout1=0.367;
Pout2=0.008		 Pin=0.027;
Pout1=0.492;
Pout2=0.067		 Pin=0.057;
Pout1=0.455;
Pout2=0.008
Group n Dampness Qi-stagnation Essence-deficiency
HIV-infected
CD4+>350 cells/μL 13 40.15±67.85 0.00±0.00 11.92±29.12
CD4+<350 cells/μL 13 80.46±75.66 18.46±35.32 21.15±40.47
AIDS 60 67.68±72.00 31.61±50.41 20.00±41.62
P value Pin=0.166;
Pout1=0.568;
Pout2=0.212		 Pin=0.072;
Pout1=0.428;
Pout2=0.509		 Pin=0.511;
Pout1=0.928;
Pout2=0.604

Table 10

Positive rate of syndrome factors of HIV/AIDS patients in Yunnan Province"

Group n Qi-deficiency Yang-deficiency Blood-deficiency Yin-deficiency
HIV-infected
CD4+>350 cells/μL 13 69.2% (9/13) 53.8% (7/13) 69.2% (9/13) 53.8% (7/13)
CD4+<350 cells/μL 13 23.1% (3/13) 15.4% (2/13) 30.7% (4/13) 23.1% (3/13)
AIDS 60 70.0% (42/60) 56.7% (34/60) 53.3% (32/60) 58.3% (35/60)
χ2 value 10.133 7.374 3.935 5.338
P value 0.006 0.025 0.140 0.069
Group n Dampness Qi-stagnation Essence-deficiency
HIV-infected
CD4+>350 cells/μL 13 61.5% (8/13) 0.0% (0/13) 23.1% (3/13)
CD4+<350 cells/μL 13 30.7% (4/13) 15.4% (2/13) 15.4% (2/13)
AIDS 60 53.3% (32/60) 31.7% (19/60) 20.0% (12/60)
χ2 value 2.837 9.525 0.256
P value 0.242 0.009 0.880

Table 11

Scores of syndrome factors of 608 HIV/AIDS patients ($\overline{x}$±s)"

Group n Qi-deficiency Blood-deficiency Dampness Yin-deficiency
HIV-infected
CD4+>350 cells/μL 104 72.20±75.07 62.64±70.60 57.58±69.92 52.37±65.43
CD4+<350 cells/μL 104 119.67±100.92 83.78±79.57 70.25±73.66 80.03±81.39
AIDS 400 172.97±87.91 115.80±79.59 112.26±72.12 112.64±80.71
P value Pin=0.001;
Pout1=0.001;
Pout2=0.001		 Pin=0.044;
Pout1=0.001;
Pout2=0.001		 Pin=0.205;
Pout1=0.001;
Pout2=0.001		 Pin=0.012;
Pout1=0.001;
Pout2=0.001
Group n Phlegm Yang-deficiency Essence-deficiency Qi-stagnation
HIV-infected
CD4+>350 cells/μL 104 45.92±58.75 32.68±53.09 18.96±37.12 4.71±22.80
CD4+<350 cells/μL 104 57.11±70.32 74.37±84.91 32.65±48.49 21.00±50.23
AIDS 400 81.81±77.17 119.01±93.82 38.33±49.02 37.44±54.31
P value Pin=0.302;
Pout1=0.001;
Pout2=0.003		 Pin=0.001;
Pout1=0.001;
Pout2=0.001		 Pin=0.034;
Pout1=0.001;
Pout2=0.290		 Pin=0.001;
Pout1=0.001;
Pout2=0.001

Table 12

Positive rate of syndrome factors of 608 HIV/AIDS patients"

Group n Qi-deficiency Blood-deficiency Dampness Yin-deficiency
HIV-infected
CD4+>350 cells/μL 104 53.8% (56/104) 50.0% (52/104) 46.1% (48/104) 29.8% (31/104)
CD4+<350 cells/μL 104 74.0% (77/104) 58.6% (61/104) 53.8% (56/104) 56.7% (59/104)
AIDS 400 91.7% (367/400) 75.7% (303/400) 79.0% (316/400) 75.5% (302/400)
χ2 value 86.961 30.869 55.319 78.518
P value 0.001 0.001 0.001 0.001
Group n Phlegm Yang-deficiency Essence-deficiency Qi-stagnation
HIV-infected
CD4+>350 cells/μL 104 41.3% (43/104) 29.8% (31/104) 21.1% (22/104) 4.8% (5/104)
CD4+<350 cells/μL 104 45.2% (47/104) 53.8% (56/104) 33.6% (35/104) 19.2% (20/104)
AIDS 400 60.5% (242/400) 72.5% (290/400) 40.0% (160/400) 35.0% (140/400)
χ2 value 16.701 67.404 12.999 42.019
P value 0.001 0.001 0.002 0.001
[1] Yang FZ, Yan JH, Wang J . Research on primordial qi injury pathogenesis of AIDS[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 2005,11(2):147-149
杨凤珍, 烟建华, 王健 . 艾滋病元气损伤病机的研究[J]. 中国中医基础医学杂志, 2005,11(2):147-149
[2] Huang SJ . Du(toxin) and the onset of AIDS[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 2004,10(7):46-47
黄世敬 . 论“毒”与艾滋病的发病[J]. 中国中医基础医学杂志, 2004,10(7):46-47
[3] Li FZ, Xu LR, Li BL . View on etiology and pathogenesis of AIDS of traditional Chinese medicine.[J]. Zhong Yi Za Zhi, 2006,47(5):395-396
李发枝, 徐立然, 李柏龄 . 中医学对艾滋病病因病机的认识[J]. 中医杂志, 2006,47(5):395-396
[4] Liu AH, Xie SP, Guo XX, Cheng WZ, Xu QL, Zhang M . A clinical analysis on acquired immunodeficiency syndrome(AIDS) from the viewpoint of damp-heat syndrome differentiation[J]. Henan Zhong Yi Xue Yuan Xue Bao, 2006,21(2):6-7
刘爱华, 谢世平, 郭选贤, 程五中, 许前磊, 张淼 . 艾滋病从湿热辨治临床分析[J]. 河南中医学院学报, 2006,21(2):6-7
[5] Xu LR, He Y, Zhang ML, Guo JZ, Zhang SX . Discussion on phlegm and stasis pathogenesis of HIV/AIDS[J]. Zhong Yi Yan Jiu, 2006,19(7):2-4
徐立然, 何英, 张明利, 郭建中, 张世玺 . HIV/AIDS痰瘀病机探讨[J]. 中医研究, 2006,19(7):2-4
[6] AIDS Study Group of Society of Infectious Diseases, Chinese Medical Association. Guideline on AIDS diagnosis and treatment[J]. Zhonghua Chuan Ran Bing Za Zhi, 2006,24(2):133-144
中华医学会感染病学分会艾滋病学组. 艾滋病诊疗指南[J]. 中华传染病杂志, 2006,24(2):133-144
[7] Wang JL. Clinical epidemiology: design, measure and evaluation of clinical research(3rd ed)[M]. Shanghai: Shanghai Scientific and Technical Publishers, 2009,( 3rd ed):177
王家良 . 临床流行病学——临床科研设计、测量与评价(第3版)[M]. 上海: 上海科学技术出版社, 2009,( 第3版):177
[8] Shen J. Statistics of traditional Chinese medicine[M]. Beijing: Science Press, 2009,126
申杰 . 中医统计学[M]. 北京: 科学出版社, 2009,126
[9] Deng TT. Diagnostics of traditional Chinese medicine[M]. Shanghai: Shanghai Scientific and Technical Publishers, 1984
邓铁涛 . 中医诊断学[M]. 上海: 上海科学技术出版社, 1984
[10] Zhang BY. Internal medicine of traditional Chinese medicine[M]. Shanghai: Shanghai Scientific and Technical Publishers, 1985
张伯臾 . 中医内科学[M]. 上海: 上海科学技术出版社, 2009,126
[11] Yao NL. Symptom differential diagnostics of traditional Chinese medicine(2nd ed)[M]. Beijing: People’s Medical Publishing House,2004,(2nd ed):
姚乃礼 . 中医症状鉴别诊断学(第2版)[M]. 北京: 人民卫生出版社,2004,(第2版):
[12] Zhu WF. Science of differentiation of syndrome factors(2nd ed)[M]. Beijing: People’s Medical Publishing House, 2008,( 2nd ed):88
朱文锋 . 证素辨证学(第2版)[M]. 北京: 人民卫生出版社, 2008,( 第2版):88
[13] Xinhua News Agency. Great achievements have been made on AIDS by major infectious disease control projects( 2011-03-29). .
[14] Pan XZ . History and implication of antiretroviral treatment of HIV/AIDS. In: Lu HZ. Conventional diagnosis and treatment of HIV/AIDS and its related diseases[M]. Shanghai: Shanghai Scientific and Technical Publishers, 2009
潘孝彰 . 艾滋病抗病毒治疗的发展史及启示.//卢洪洲. 艾滋病及其相关疾病诊疗常规[M]. 上海: 上海科学技术出版社, 2009
[15] He QY, Wang J . Research on TCM syndromes and diagnosis of patients after percutaneous coronary intervention based on cluster analysis[J]. Zhong Yi Za Zhi, 2008,49(10):918-921
何庆勇, 王阶 . 基于聚类分析的冠心病介入术后中医证候分类及诊断[J]. 中医杂志, 2008,49(10):918-921
[16] Wang YQ, Lang QB, Li GG, He XH, He JC, Yan X, Zhuang YH, Ye J, Guo YJ, Lu X, Li FF, Zhao LY, Yan HX, Xu GH, Wang HF . Study on diagnostic standard for dampness syndrome in patients with chronic gastritis[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2005,25(11):975-979
王忆勤, 郎庆波, 李果刚, 何新慧, 何建成, 颜新, 庄燕鸿, 叶进, 郭永洁, 陆雄, 李福凤, 赵立宇, 燕海霞, 徐贵华, 王惠芳 . 慢性胃炎中医湿证证候诊断标准研究[J]. 中国中西医结合杂志, 2005,25(11):975-979
[17] Wang Z, Zhang BL, Shen CD, Chen QG, Wang YY . Multivariate analysis of TCM syndrome of stroke[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2003,23(2):106-109
doi: 10.7661/CJIM.2003.2.106
王忠, 张伯礼, 申春娣, 陈启光, 王永炎 . 中医中风病证候的多元统计分析[J]. 中国中西医结合杂志, 2003,23(2):106-109
doi: 10.7661/CJIM.2003.2.106
[18] Chen QG, Shen CD, Zhang HQ, Fu WM, Min J, Wang CS, Li YP, Zhu J, Shi SF, Zhu XY, Chen XH, Shi L, Xu LH, Chang H . Application of structural equation model in standartdization of syndrome differentiation[J]. Zhongguo Wei Sheng Tong Ji, 2005,22(1):2-4
doi: 10.3969/j.issn.1002-3674.2005.01.001
陈启光, 申春娣, 张华强, 符为民, 闵捷, 王澄淑, 郦永平, 朱佳, 史锁方, 朱学云, 陈晓虎, 石磊, 徐丽华, 常惠 . 结构方程模型在中医证候规范标准研究中的应用[J]. 中国卫生统计, 2005,22(1):2-4
doi: 10.3969/j.issn.1002-3674.2005.01.001
[19] Tang QS, Qu M, Bao ZX, Wang Y, Ma L . Bayesian network research on TCM syndromes of depression[J]. Zhong Yi Za Zhi, 2008,49(11):1013-1015
doi: 10.3321/j.issn:1001-1668.2008.11.027
唐启盛, 曲淼, 包祖晓, 王耘, 马良 . 抑郁症中医证候的贝叶斯网络研究[J]. 中医杂志, 2008,49(11):1013-1015
doi: 10.3321/j.issn:1001-1668.2008.11.027
[20] Wang L, Su Y, Zhang Q, Liu P, Su SB . Classification and modeling of traditional Chinese medicine syndromes in patients with posthepatitic cirrhosis by partial least-squares[J]. J Chin Integr Med, 2008,6(11):1122-1128
王磊, 苏越, 张琴, 刘平, 苏式兵 . 偏最小二乘法在肝炎后肝硬化中医证候分类建模中的应用[J]. 中西医结合学报, 2008,6(11):1122-1128
[21] Peng B, Li HW, Xie SP, Guo XX, Guo HJ, Hu YP, Li QY . Discussion on AIDS virus injurying primordial qi[J]. Zhonghua Zhong Yi Yao Za Zhi, 2010,25(1):17-20
彭勃, 李华伟, 谢世平, 郭选贤, 郭会军, 胡研萍, 李青雅 . 论艾毒伤元[J]. 中华中医药杂志, 2010,25(1):17-20
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