1 069例冠心病患者冠状动脉造影与中医证候特点

doi:10.3736/jcim20080208

Abstract

Objective:To study the characteristics of coronary arteriography and traditional Chinese medicine syndrome of 1 069 patients with coronary artery disease (CAD).

Methods:One thousand and sixty-nine patients with CAD were investigated by epidemiological method. The patients were divided into young patients (n=82, aged 45 years or younger) and middle-aged and old patients (n=987, older than 45 years). The characteristics of the two groups were analyzed, including clinical data, coronary arteriography and traditional Chinese medicine syndrome.

Results:Compared with middle-aged and old patients, proportion of male, triglyceride, total cholesterol, smoking patients, acute myocardial infarction and family history of CAD in young patients were significantly higher (P<0.05). Patients accompanying with hypertension and diabetes in middle-aged and old patients were more than those in young patients (P<0.05). Occurrence rates of morbidity of left circumflex coronary artery, left main coronary artery and multi-branch were higher in middle-aged and old patients (P<0.05), however, the occurrence rates of morbidity of single and doublebranch were higher in young patients (P<0.05). The occurrence rates of syndromes of qi stagnation and phlegm turbidity in young patients were higher than those in middleaged and old patients (P<0.05). But the proportions of cold coagulation, yin deficiency, yang deficiency and kidney deficiency in middle-aged and old patients were obviously higher (P<0.05).

Conclusion:The traditional Chinese medicine syndrome and pathological changes of CAD in young patients are different from those in old patients.

Key words: coronary heart disease, coronary arteriography, symptom complex, youth

CLC Number:

R541.4

Jie Wang, Yan-wei Xing, Jian-xin Chen, Qing-yong He, Yong-hong Gao, Zun Li. Characteristics of coronary arteriography and traditional Chinese medicine syndrome of 1 069 patients with coronary artery disease. Journal of Chinese Integrative Medicine, 2008, 6(2): 148-152.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20080208

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References 11

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Items	Young patients(n=82, ≤45 years)	Middle-aged and old patients (n=987, >45 years)	P
Male [Cases (%)]	76 (93.0)	696 (70.5)	0.00
Age($\bar{x}$±s, year)	40.52±4.38	62.98±9.52	0.00
Blood lipid
TG ($\bar{x}$±s, mmol/L)	2.41±1.54	1.46±0.68	0.00
TC($\bar{x}$±s, mmol/L)	4.73±1.17	4.04±1.02	0.04
HDL($\bar{x}$±s, mmol/L)	1.04±0.83	1.16±0.38	0.96
LDL($\bar{x}$±s, mmol/L)	2.96±1.05	2.66±0.73	0.61
Risk factor
Smoking [Cases (％)]	63 (83)	499 (51)	0.00
HBP [Cases (％)]	34 (41)	636 (64)	0.00
Diabetes [Cases (％)]	8 (10)	247 (25)	0.01
Acute myocardial infarction [Cases (％)]	11 (13)	27 (3)	0.01
Family history [Cases (％)]	28 (34)	117 (12)	0.00

Group	n	Civil servant	Peasant	Staff	Driver
Young patients	82	14 (17)	15 (18)	10 (12)	12 (15)
Middle-aged and old patients	987	341 (35)	174 (18)	122 (12)	7 (1)
P		0.00	1	1	0.00

Group	n	LM	LAD	LCX	RCA	Single branch	Double branch	Multi-branch
Young patients	82	5 (6)	78 (95)	40 (49)	42 (51)	28 (34)	27 (33)	27 (33)
Middle-aged and old patients	987	152 (15)	907 (92)	702 (71)	624 (63)	131 (12)	141 (14)	715 (72)
P		0.03	0.87	0.03	0.08	0.01	0.01	0.00

Syndrome	Young patients (n=82)	Middle-aged and old patients (n=987)	P
Qi stagnation	18 (22)	109 (11)	0.03
Blood stasis	54 (66)	663 (67)	0.98
Phlegm turbidity	40 (49)	330 (33)	0.04
Cold coagulation	0 (0)	25 (3)	0.04
Heat accumulation	17 (21)	123 (13)	0.13
Qi deficiency	52 (63)	683 (69)	0.87
Yin deficiency	22 (27)	383 (39)	0.04
Yang deficiency	6 (7)	198 (20)	0.01
Heart deficiency	3 (4)	100 (10)	0.09
Liver deficiency	8 (10)	119 (12)	0.77
Spleen deficiency	5 (6)	71 (7)	0.98
Kidney deficiency	12 (15)	311 (32)	0.01
Lung deficiency	8 (10)	60 (6)	0.21

Characteristics of coronary arteriography and traditional Chinese medicine syndrome of 1 069 patients with coronary artery disease

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