Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2007, Vol. 5 ›› Issue (1): 92-96.doi: 10.3736/jcim20070119

Special Issue: Traditional Chinese Medicine

• Literature Review • Previous Articles     Next Articles

Progress in research of traditional Chinese medicine in inducing differentiation of human hepatoma cells

Xiao-yan Mu, Ai-guang Zhao   

  1. Department of Oncology, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, ChinaAbstract
  • Online:2007-01-31 Published:2007-01-21

Key words: Chinese herbal drugs, liver cancer, cyclic adenosine monophosphate, transduction, cell differentiation

CLC Number: 

  • R575
[1] 王英凯, 张明磊, 张立波 . 人参三醇组皂甙诱导分化人肝癌细胞的研究[J]. 临床肝胆病杂志, 2003,19(4):242-243
Wang YK, Zhang ML, Zhang LB . Study on ginsenosides induced differentiation of human hepatocellular carcinoma cells[J]. Lin Chuang Gan Dan Bing Za Zhi, 2003,19(4):242-243
[2] 曾小莉, 涂植光 . 人参皂甙Rh2对人肝癌细胞SMMC-7721的诱导分化作用[J]. 癌症, 2004,23(8):879-884
Zeng XL, Tu ZG . Induction of differentiation by ginsenoside Rh2 in hepatocarcinoma cell SMMC-7721[J]. Ai Zheng, 2004,23(8):879-884
[3] 皇甫超申, 耿旭, 谷敬丽 , 等. 苦参碱诱导SMMC-7721细胞分化过程中细胞骨架的改变[J]. 河南大学学报(医学版), 2006,25(2):12-14
Huangfu CS, Geng X, Gu JL , et al. Change on cytoskeleton of SMMC-7721 cell lines differentiation induced by matrine[J]. Henan Da Xue Xue Bao Yi Xue Ban, 2006,25(2):12-14
[4] 袁淑兰, 黄韧敏, 王修杰 , 等. 丹参酮对人肝癌细胞某些表型的逆转作用[J]. 肿瘤, 1997,17(5):268-270
Yuan SL, Huang RM, Wang XJ , et al. The reversing effect of tanshinone on malignant phenotype of human hepatocarcinoma cell line[J]. Tumor, 1997,17(5):268-270
[5] 张燕军, 夏天, 赵建斌 . 苦参碱对SMMC-7721细胞系的诱导分化作用[J]. 第四军医大学学报, 1998,19(3):340-343
Zhang YJ, Xia T, Zhao JB . Effects of Matrine on the differentiation of SMMC-7721 cell lines[J]. Di Si Jun Yi Da Xue Xue Bao, 1998,19(3):340-343
[6] 曾小莉, 涂植光 . 人参总皂甙诱导人肝癌细胞分化初探[J]. 肿瘤防治研究, 2000,27(3):188-190
Zeng XL, Tu ZG . The preliminary study of induced differentiation of total saponins of Panax ginseng on human hepatoma cell line[J]. Zhong Liu Fang Zhi Yan Jiu, 2000,27(3):188-190
[7] 彭安, 陈敏珍, 袁劲松 . 葛根提取物诱导人肝癌细胞分化的研究[J]. 现代中西医结合杂志, 2002,11(16):1533-1534
Peng A, Chen MZ, Yuan JS . Reverse effects of root kudzuvine extraction on the malignant phenotype of Bel-7402 human malignant hepatoma cells[J]. Xian Dai Zhong Xi Yi Jie He Za Zhi, 2002,11(16):1533-1534
[8] 解方为, 欧阳学农, 蒋明德 . 红景天甙对人肝癌细胞的诱导分化作用[J]. 西南国防医药, 2005,15(6):613-615
Xie FW, Ouyang XN, Jiang MD . The effect of salidroside on induction of differentiation of SMMC-7721 cell lines[J]. Xi Nan Guo Fang Yi Yao, 2005,15(6):613-615
[9] 袁冬生, 王新华, 刘冬辉 , 等. 中药复方肝癌宁对肝癌细胞生长和AFP分泌的抑制作用[J]. 世界华人消化杂志, 2006,14(19):1912-1915
Yuan DS, Wang XH, Liu DH , et al. Inhibitory affect of composite Gan’aining on growth and alpha-fetoprotein secretion of human hepatoma cells[J]. Shi Jie Hua Ren Xiao Hua Za Zhi, 2006,14(19):1912-1915
[10] 周建锋, 王怡兵 . 不同扶正药物及其配伍对SMMC-7721人肝癌细胞的诱导分化作用[J]. 中国中医药科技, 2001,8(2):75-76
Zhou JF, Wang YB . Effects of drugs supporting healthy energy and their compositions on induction and differentiation of hepatocarcinoma cell SMMC-7721[J]. Zhongguo Zhong Yi Yao Ke Ji, 2001,8(2):75-76
[11] 刘平, 周建锋, 胡义扬 , 等. 益气养阴诱导SMMC-7721肝癌细胞分化作用与意义[J]. 中国中医基础医学杂志, 2000,6(8):29-34
Liu P, Zhou JF, Hu YY , et al. Effect and significance of "benefiting qi and nourishing yin"on induction of hepatoma cell differentiation[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 2000,6(8):29-34
[12] 陆世伦 . 细胞信号转导与肿瘤. //汤钊猷. 现代肿瘤学. 第2版, 上海:上海医科大学出版社. 2000: 189-201.,,():
Chen SL. Cell signal transduction and tumor. In: Tang ZY. Modern oncology. 2nd ed. Shanghai: Shagnhai Medical University Press. 2000: 189-201. Chinese.,,():
[13] 管冬元, 鲁恒心, 方肇勤 . 不同中医治法对ras/MAPK信号通路相关基因转录调节的实验研究[J]. 中国中医基础医学杂志, 2002,8(10):36-38
Guan DY, Lu HX, Fang ZQ . Study on the regulation of different therapies on some signal moleculars transcriptions in the pathway of ras/MAPK[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 2002,8(10):36-38
[14] 农朝赞, 郭凌霄, 黄华艺 . 芒果甙对肝癌大鼠肝组织β-catenin和p120ctn表达的影响[J]. 右江民族医学院学报, 2003,25(2):143-146
Nong CZ, Guo LX, Huang HY . Effect of Mangiferin on the expression of β-catenin and p120ctn in hepatic tissues of rats with liver cancer[J]. Youjiang Min Zu Yi Xue Yuan Xue Bao, 2003,25(2):143-146
[15] 王继伟, 戴书静, 牛建昭 . 金雀黄素抑制人肝癌细胞Bel 7402中NF-κB表达的实验研究[J]. 北京中医药大学学报, 2001,24(5):16-19, 44
Wang JW, Dai SJ, Niu JZ , et al. Experimental study of the inhibiting effects of genistein on the expression of NF-κB in human hepatic cancer cell strain Bel 7402[J]. Beijing Zhong Yi Yao Da Xue Xue Bao, 2001,24(5):16-19, 44
[16] 曾小莉, 涂植光 . 人参皂甙Rh2对人肝癌细胞SMMC-7721信号传导的影响[J]. 中华肝脏病杂志, 2004,12(9):565-566
Zeng XL, Tu ZG . Effects of ginsenoside Rh2 on signal transduction in hepatocarcinoma SMMC-7721 cells[J]. Zhonghua Gan Zang Bing Za Zhi, 2004,12(9):565-566
[17] 胡兵, 安红梅, 李新民 . 龙力胶囊对人肝癌细胞诱导分化及机理研究[J]. 成都中医药大学学报, 2000,23(1):46-48
Hu B, An HM, Li XM . A study of Longli Capsule induced differentiation of human heptocarcinoma cell lines HCC-9204 and it's mechanism[J]. Chengdu Zhong Yi Yao Da Xue Xue Bao, 2000,23(1):46-48
[18] 赵海磊, 刘成, 赵爱光 . 中药复方胃肠安血清诱导肝癌SMMC-7721细胞分化[J]. 世界华人消化杂志, 2003,11(9):1345-1348
Zhao HL, Liu C, Zhao AG , et al. Differentiation of hepatocellular carcinoma SMMC-7721 cell line induced by Chinese medicine recipe[J]. Shi Jie Hua Ren Xiao Hua Za Zhi, 2003,11(9):1345-1348
[19] 司维柯, 高利宏, 刘斌 , 等. 苦参碱诱导人肝癌细胞分化、凋亡时对G1细胞周期调节因子的调控[J]. 癌症, 2001,20(8):848-851
Si WK, Gao LH, Liu B , et al. Regulation of G1 phase cell cycle regulation factors in differentiation and apoptosis of matrine-induced hepatoma cells[J]. Ai Zheng, 2001,20(8):848-851
[20] 解方为, 欧阳学农, 蒋明德 . 红景天甙对人肝癌细胞c-myc 表达的逆转作用[J]. 西南国防医药, 2006,16(2):130-131
Xie FW, Ouyang XN, Jiang MD . Reverse effects of salidroside on expression of c-myc in SMMC-7721 cell line in vitro[J]. Xi Nan Guo Fang Yi Yao, 2006,16(2):130-131
[21] 张秀华, 杨海申, 王朝晖 , 等. 端粒酶活性检测在大肠癌早期诊断中的应用[J]. 医师进修杂志, 2000,23(7):40-41
Zhang XH, Yang HS, Wang ZH , et al. Application of detection of telomerase activity in the early diagnosis of colorectal cancer[J]. Yi Shi Jin Xiu Za Zhi, 2000,23(7):40-41
[22] 梁永红, 侯华新, 黎丹戎 , 等. 板蓝根二酮B体外抗癌活性研究[J]. 中草药, 2000,31(7):531-533
Liang YH, Hou HX, Li DR , et al. Studies on in vitro anticancer activity of tryptanthrin B[J]. Zhong Cao Yao, 2000,31(7):531-533
[23] 杨大国, 邓欣, 李知玉 , 等. 正肝方药物血清诱导人肝癌细胞分化的体外实验研究[J]. 中国中西医结合杂志, 2004,24(2):140-142
Yang DG, Deng X, Li ZY , et al. Experimenal study on differentiation of human hepatocarcinoma cells induced by Zhengganfang drug serum in vitro[J]. Zhongguo Zhong Xi Yi Jie He Za Zhi, 2004,24(2):140-142
[24] 曾小莉, 涂植光 . 端粒酶在人参皂甙Rh2诱导肝癌细胞分化中的作用[J]. 癌症, 2004,23(12):1655-1659
Zeng XL, Tu ZG . Effect of telomerase on ginsenoside Rh2-induced differentiation of hepatocarcinoma cell line SMMC-7721[J]. Ai Zheng, 2004,23(12):1655-1659
[25] 黄炜, 黄济群, 张东方 , 等. 桂皮酸诱导BEL-7402人肝癌细胞分化的研究[J]. 实用癌症杂志, 2000,15(1):12-15
Huang W, Huang JQ, Zhang DF , et al. Differentiation of BEL-7402 human hepatocarcinoma cells induced by cinnamic acid[J]. Shi Yong Ai Zheng Za Zhi, 2000,15(1):12-15
[26] 杨雁, 宋少刚, 陈敏珠 . 黄芪总提物对肝癌细胞生长、甲胎蛋白分泌及γ-GT活性的影响[J]. 中国临床药理学与治疗学, 2001,6(1):18-20
Yang Y, Song SG, Chen MZ . Effects of the total extract of astragalosides on the growth, AFP secretion and γ-GT activity of human hepatoma cells[J]. Zhongguo Lin Chuang Yao Li Xue Yu Zhi Liao Xue, 2001,6(1):18-20
[27] 李祺福, 欧阳高亮, 刘庆榕 , 等. 中国鲎鲎素诱导人肝癌SMMC-7721细胞分化的观察[J]. 癌症, 2002,21(5):480-483
Li QF, Ouyang GL, Liu QR , et al. Tachyplesin-induced diferentiation of human hepatocarcinoma cell line SMMC-7721[J]. Ai Zheng, 2002,21(5):480-483
[1] Gai Ran, Xi-lin Feng, Yi-lin Xie, Qing-yun Zheng, Peng-peng Guo, Ming Yang, Ying-lu Feng, Chen Ling, Li-qing Zhu, Chen Zhong. The use of miR122 and its target sequence in adeno-associated virus-mediated trichosanthin gene therapy. Journal of Integrative Medicine, 2021, 19(6): 515-525.
[2] Hao Gou, Ruo-chen Huang, Yong-hua Su, Wei Li. Design of dual targeting immunomicelles loaded with bufalin and study of their anti-tumor effect on liver cancer. Journal of Integrative Medicine, 2021, 19(5): 408-417.
[3] Liang Ding, Xin-you Zhang, Di-yao Wu, Meng-ling Liu. Application of an extreme learning machine network with particle swarm optimization in syndrome classification of primary liver cancer. Journal of Integrative Medicine, 2021, 19(5): 395-407.
[4] Syed Nasir Abbas Bukhari, Fahad Hussain, Hnin Ei Thu, Zahid Hussain. Synergistic effects of combined therapy of curcumin and Fructus Ligustri Lucidi for treatment of osteoporosis: cellular and molecular evidence of enhanced bone formation. Journal of Integrative Medicine, 2019, 17(1): 38-45.
[5] Chang-quan Ling, Jia Fan, Hong-sheng Lin, Feng Shen, Zhen-ye Xu, Li-zhu Lin, Shu-kui Qin, Wei-ping Zhou, Xiao-feng Zhai, Bai Li, Qing-hui Zhou, on behalf of the Chinese Integrative Therapy of Primary Liver Cancer Working Group. Clinical practice guidelines for the treatment of primary liver cancer with integrative traditional Chinese and Western medicine. Journal of Integrative Medicine, 2018, 16(4): 236-248.
[6] Paul Avijit, Das Sreemanti, Das Jayeeta, Samadder Asmita, Bishayee Kausik, Sadhukhan Ratan, Anisur Rahman Khuda-Bukhsh. Diarylheptanoid-myricanone isolated from ethanolic extract of Myrica cerifera shows anticancer effects on HeLa and PC3 cell lines: Signalling pathway and drug-DNA interaction. Journal of Chinese Integrative Medicine, 2013, 11(6): 405-415.
[7] Di Li, Guan-liang Wang, Meng-ya Shan, Jia-han Liu, Lin Wang, De-zeng Zhu. Effects of ursolic acid on c-Cbl-associated protein expression in 3T3-L1 adipocytes with insulin resistance. Journal of Chinese Integrative Medicine, 2012, 10(8): 886-893.
[8] Jin-bin Han, Yong-qiang Hua, Lian-yu Chen, Lu-ming Liu . Advances in Smoothened-targeting therapies for pancreatic cancer: Implication for drug discovery from herbal medicines. Journal of Chinese Integrative Medicine, 2012, 10(3): 256-263.
[9] Yang Chen, Jian-hua Huang, You Ning, Zi-yin Shen. Icariin and its pharmaceutical efficacy: Research progress of molecular mechanism. Journal of Chinese Integrative Medicine, 2011, 9(11): 1179-1184.
[10] Shou-fu Wang, Hui-jian Zhang, Jian-sheng Li, Jin-li Qin, Su-yun Li, Hai-bin Yu, Feng Wang, Ya Li, Si-hua Liu. Effects of Chinese herbal medicine Dusuqing Granule on toll-like receptor 4 signaling in multiple organ injury induced by bacterial pneumonia in aged rats. Journal of Chinese Integrative Medicine, 2011, 9(1): 84-90.
[11] Ming-hui Yang, Min Li, Yong-qi Dou, Yi Liu, Xiao-dong Luo, Jian-zong Chen, Heng-jun Shi. Effects of Bushen Huoxue Granule on motor function in patients with Parkinson’s disease: A multicenter, randomized, double-blind and placebo-controlled trial. Journal of Chinese Integrative Medicine, 2010, 8(3): 231-237.
[12] Ya-bing Zhou, Jian-er Yu, Jie Wu, Li Bai, Li-li Huo, Xin-guang Zhang, Li-qing Li . Effects of Chinese herbal medicine Bushen Gubiao Recipe on toll-like receptor 4 and CD4 +CD25 +foxp3 +regulatory T cells in mice with recurrent respiratory tract infections. Journal of Chinese Integrative Medicine, 2010, 8(11): 1053-1059.
[13] Bing Hu , Hong-mei An , Ke-ping Shen , Qin Du. Senescence-inducing effects of Chinese herbal medicine Tenglong Buzhong Decoction on human colon carcinoma LS-174-T cells and the mechanism. Journal of Chinese Integrative Medicine, 2010, 8(11): 1048-1052.
[14] Wei Xu, Meng Shi, Jian-gang Liu, Cheng-long Wang . Collagen protein expressions in ischemic myocardium of rats with acute myocardial infarction and effects of qi-tonifying, yin-tonifying and blood-activating herbs and detoxifying and blood-activating herbs. Journal of Chinese Integrative Medicine, 2010, 8(11): 1041-1047.
[15] Wen-jun Wang, Da-jin Li, Jun Li, Wen-jiang Zhou. An in vitro study on neuroprotective effects of serum containing Gengnianchun decoction and its main monomers against amyloid beta protein-induced cellular toxicity. Journal of Chinese Integrative Medicine, 2010, 8(1): 67-73.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Jin-rong Fu. Establishment of multivariate diagnosis and treatment system of modern gynecology of traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 22-24
[2] Hao Li, Ming-jiang Yao, Wen-ming Zhao, Jie Guan, Lin-lin Cai, Ling Cui. A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment. Journal of Chinese Integrative Medicine, 2008, 6(1): 25-31
[3] Zhi-chun Jin. Problems in establishing clinical guideline for integrated traditional Chinese and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 5-8
[4] SUN Ming-yu, ZUO Jian, DUAN Ji-feng, HAN Jun, FAN Shi-ming, ZHANG Wei, ZHU Li-fang, YAO Ming-hui. Antitumor activities of kushen flavonoids in vivo and in vitro. Journal of Chinese Integrative Medicine, 2008, 6(1): 51-59
[5] Min Cheng, Qiong Feng, Shu-wen Qian, Hui Gao, Cui-qing Zhu. Preliminary assay of p-amyloid binding elements in heart-beneficial recipe. Journal of Chinese Integrative Medicine, 2008, 6(1): 68-72
[6] Ning-qun Wang, Liang-duo Jiang, Zong-xing Li. Research progress in asthma-related quality of life. Journal of Chinese Integrative Medicine, 2008, 6(1): 93-97
[7] Jing-yuan Mao, Chang-xiao Liu, Heng-he Wang, Guang-li Wei , Zhen-peng Zhang, Jie Xing, Wang Xian liang , Ying-fei Bi . Effects of Shenmai Injection on serum concentration and pharmacokinetics of digoxin in dogs with heart failure. Journal of Chinese Integrative Medicine, 2010, 8(11): 1070-1074
[8] Zhi-mei Wang, Bin Zhang. A study on translation of ellipses in Huangdi Neijing from perspective of hermeneutic theory. Journal of Chinese Integrative Medicine, 2010, 8(11): 1097-1100
[9] Gui Yu, Jie Wang. Thinking on building the network cardiovasology of Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(11): 1206-1210
[10] Pedro Saganha João, Doenitz Christoph, Greten Tobias, Efferth Thomas, J. Greten Henry. Qigong therapy for physiotherapists suffering from burnout: a preliminary study. Journal of Chinese Integrative Medicine, 2012, 10(11): 1233-1239