In-house preparation and characterization of an Ayurvedic bhasma: Praval bhasma

doi:10.1016/S2095-4964(14)60005-4

Abstract

Objective

To prepare the Praval bhasma (PB) and to perform its characterization.

Methods

The preparation was performed strictly as per method prescribed in Ayurvedic formulary of India followed by preliminary tests including Nischandratva, Rekhapurnatvam, Varitaramtavm, Nisvadutvam and Amla pariksha. The physicochemical characterization was done with the use of instrumental techniques such as Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), X ray diffraction (XRD), and energy dispersive X-ray (EDAX).

Results

The FTIR bands appearing in final product spectra showed a significant shift in infrared vibration frequency as well as intensity when compared with the raw material, which was indicative of formulation of bhasma. The XRD analysis revealed that raw material contained CaCO3 whereas in case of final product of bhasma, CaO was identified. SEM analysis revealed the difference in particles size of bhasma (10-15 μm) and raw material (100-150 μm). The EDAX analysis showed presence of different concentration of carbon in both the samples.

Conclusion

It may be concluded that modern analytical techniques may be involved to evaluate the quality aspects of PB. The findings of the present research work may be helpful for further formulation and standardization of PB in routine analysis.

Key words: Praval bhasma, Characterization, Ayurveda, Preparation process

Amrita Mishra, Arun K. Mishra, Om Prakash Tiwari, Shivesh Jha. In-house preparation and characterization of an Ayurvedic bhasma: Praval bhasma. Journal of Integrative Medicine, 2014, 12(1): 52-58.

/ / Recommend

Add to citation manager EndNote| Reference Manager|ProCite|BibTeX|RefWorks

URL: http://www.jcimjournal.com/EN/10.1016/S2095-4964(14)60005-4

http://www.jcimjournal.com/EN/Y2014/V12/I1/52

TrendMD

Figures/Tables 9

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

References 16

[1]	Mishra S. . Ayurvedeeya Rasashastra 11th ed[M]. Varanasi: Chaukhambha Orientalia, 2006: 15-27
[2]	Sharma S . Rasatarangini[M]. Varanasi: Motilal Banarsi Das, 1979: 45-51
[3]	Gupta G . Bharata bhaisajya ratnakara[M]. Gujarat: Unjha Pharmacy, 1947: 56-61
[4]	Bhatta GK . Rasendra sara sangraha[M]. Varanasi: Chaukhambha Krishnadas Academy, 1937: 220-226
[5]	Acharya VYT . Rasamrtam[M]. Varanasi: Motilal Banarsi Das, 1951: 58-62
[6]	Das G . Bhaisajya ratnawali[M].Delhi: Motilal Banarsi Das, 1884:152-154
[7]	Basavaraja VS . Basavarajiyam[M]. Delhi: Motilal Banarsi Das, 1986: 12-14
[8]	Acharya VYT . Siddhayoga sangraha[M]. Calcutta: Baidyanath Ayurved Bhavan, 2010: 135-140
[9]	Galib, Kar AC , Narayana A.Standardization of bhasmas - need of the hour[J]. J Ayurveda, 2008,2:27-33
[10]	Tripathi YB . A multidisciplinary approach to standardize bhasmas(Ayurvedic metallic preparations)[J]. Curr Sci, 2006,90(7):897-898 doi: 10.3109/00498257209111044
[11]	. Lipnick RL, Cotruvo JA, Hill RN, Bruce RD, Stitzel KA, Walker AP, Chu I, Goddard M, Segal L, Springer JA, et al.Comparison of the up-and-down, conventional LD50, and fixed-dose acute toxicity procedures. Food Chem Toxicol. 33(3):223-231. doi: 10.1016/0278-6915(94)00136-C pmid: 7896233
[12]	Bhojashettar S, Jadar PG, Rao VN . Pharmaceutical study of Yashadabhasma[J]. Anc Sci Life, 2012,31(3):90-94 doi: 10.4103/0257-7941.103181 pmid: 23284213
[13]	The Ayurvedic formulary of India. Delhi: Council for Research in Ayurved and Siddha, Ministry of Health and Family Welfare, Government of India. 2003: 237-240.
[14]	Modi MB, Donga SB, Dei L . Clinical evaluation of Ashokarishta, Ashwagandha Churna and Praval Pishti in the management of menopausal syndrome[J]. Ayu, 2012,33(4):511-516 doi: 10.4103/0974-8520.110529
[15]	Reddy PN, Lakshmana M, Udupa UV . Effect of Praval bhasma(Coral calx), a natural source of rich calcium on bone mineralization in rats[J]. Pharmacol Res, 2003,48(6):593-599 doi: 10.1016/S1043-6618(03)00224-X
[16]	Shah J, Goyal R . Investigation of neuropsychopharmacological effects of a polyherbal formulation on the learning and memory process in rats[J]. J Young Pharm, 2011,3(2):119-124 doi: 10.4103/0975-1483.80296

Metrics

Viewed

Full text

Abstract

Cited

Shared

Discussed

Comments

Recommended 10

[1]	Dong Yang, Yong-ping Du, Qing Shen, Wei Chen, Yan Yu, Guang-lei Chen. Expression of alpha-smooth muscle actin in renal tubulointerstitium in patients with kidney collateral stasis. Journal of Chinese Integrative Medicine, 2008, 6(1): 41-44
[2]	Hai-feng Wei, Bai-liu Ya, Ling Zhao, Cui-fei Ye, Li Zhang, Lin Li. Evaluation of tongue manifestation of blood stasis syndrome and its relationship with blood rheological disorder in a rat model of transient brain ischemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 73-76
[3]	Xi Lin, Jian-ping Liu. Herbal medicines for viral myocarditis. Journal of Chinese Integrative Medicine, 2008, 6(1): 76
[4]	Xi Lin, Jian-ping Liu. Tai chi for treating rheumatoid arthritis. Journal of Chinese Integrative Medicine, 2008, 6(1): 82
[5]	Liang-ping Hu, Hui Gao. Discrimination of errors in statistical analysis of medical papers published in the first issue of 2006 in Journal of Chinese Integrative Medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 98-106
[6]	Yan-bo Zhu , Qi Wang, Cheng-yu Wu, Guo-ming Pang, Jian-xiong Zhao, Shi-lin Shen, Zhong-yuan Xia , Xue Yan . Logistic regression analysis on relationships between traditional Chinese medicine constitutional types and overweight or obesity. Journal of Chinese Integrative Medicine, 2010, 8(11): 1023-1035
[7]	Wei Xu, Meng Shi, Jian-gang Liu, Cheng-long Wang . Collagen protein expressions in ischemic myocardium of rats with acute myocardial infarction and effects of qi-tonifying, yin-tonifying and blood-activating herbs and detoxifying and blood-activating herbs. Journal of Chinese Integrative Medicine, 2010, 8(11): 1041-1047
[8]	Tao Wang , Feng Qin. Effects of Chinese herbal medicine Xiaoyao Powder on monoamine neurotransmitters in hippocampus of rats with postpartum depression. Journal of Chinese Integrative Medicine, 2010, 8(11): 1075-1079
[9]	Ying Xu , Chang-chun Zeng , Xiu-yu Cai , Rong-ping Guo , Guang Nie , Ying Jin. Chromaticity and optical spectrum colorimetry of the tongue color in different syndromes of primary hepatic carcinoma. Journal of Chinese Integrative Medicine, 2012, 10(11): 1263-1271
[10]	Xiang-ying Mao , Qin Bian , Zi-yin Shen. Analysis of the osteogenetic effects exerted on mesenchymal stem cell strain C3H10T1/2 by icariin via MAPK signaling pathway in vitro. Journal of Chinese Integrative Medicine, 2012, 10(11): 1272-1278