胃癌中医证型与临床相关因素的多因素分析

doi:10.3736/jcim20070506

Abstract

Objective: The research is aimed at investigating the developing rule and the relationship between syndrome differentiation in traditional Chinese Medicine (TCM) and clinical factors of gastric cancer so as to guide clinical work and indicate prognosis.Methods: We collected the medical records and the information of four diagnostic methods of 325 cases of gastric cancer sufferers in the way of clinical epidemiological survey, and divided them into 6 syndromes including dysfunction of spleen, disharmony of liver and stomach, blood stagnation in stomach, yin deficiency of stomach, phlegm dampness stagnation and deficiency of both qi and blood. Then we used logistic regression analysis to analyze the relationship between syndrome differentiation and clinical-related factors such as age, gender, Karnofsky score and clinical stage, etc.Results: The syndrome spleen dysfunction is a dominant one among the syndromes of stomach cancer. Disharmony of liver and stomach always happens in early stage of stomach cancer and is frequently seen in women. Patients with syndrome of phlegm dampness stagnation or deficiency of both qi and blood have lower Karnofsky score and poorer living quality. Syndromes of blood stagnation in stomach and yin deficiency of stomach show no relationship with the clinical factors in this research.Conclusion: >Syndrome differentiation in TCM of gastric cancer is related to some clinical factors to a certain extent.

Key words: gastric cancer, traditional Chinese medicine, clinical factor, logistic regression analysis

CLC Number:

R735.2

Li Tao, Jin-kun Yang. Multifactor analysis of syndrome differentiation in traditional Chinese medicine and clinical correlative factors in gastric cancer. Journal of Chinese Integrative Medicine, 2007, 5(5): 510-513.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20070506

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References 8

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Variable	B	Std. Error	Wald	Sig	Exp (B)
KPS score	–0.118	0.026	19.990	0.000	0.889
Suffering time	–0.135	0.450	0.090	0.764	0.874
Surgical mode	1.697	1.865	0.828	0.363	5.459
Course of chemotherapy	0.181	0.291	0.388	0.533	1.199
Metastasis	–5.700	3.177	3.220	0.073	0.003

Variable	B	Std. Error	Wald	Sig	Exp (B)
Sex	–0.834	0.419	3.958	0.047	0.434
Clinical stage	0.694	0.245	8.005	0.005	2.002
Surgical mode	14.797	3 035.240	0.000	0.996	2 668 188.125
Metastasis	13.238	3 762.011	0.000	0.997	561 166.319

Variable	B	Std. Error	Wald	Sig	Exp (B)
KPS score	0.045	0.087	0.266	0.606	1.046
Clinical stage	–1.385	1.631	0.721	0.396	0.250
Surgical mode	–0.121	20 943.250	0.000	1.000	0.886
Suffering time	16.063	5 551.222	0.000	0.998	9 461 739
Metastasis	19.607	34 756.010	0.000	1.000	330 000 000

Variable	B	Std. Error	Wald	Sig	Exp (B)
KPS score	0.031	0.015	4.180	0.041	1.032
Clinical stage	–0.295	0.219	1.810	0.178	0.745

Variable	B	Std. Error	Wald	Sig	Exp (B)
KPS score	0.240	0.101	5.640	0.018	1.272
Clinical stage	–1.388	5.375	0.067	0.796	0.249
Surgical mode	–5.070	4.178	1.473	0.225	0.006
Course of chemotherapy	–1.432	2.044	0.491	0.483	0.239
Suffering time	13.838	5 036.177	0.000	0.998	1 022 294
Relapse	0.052	35.530	0.000	0.999	1.053
Metastasis	7.950	8.065	0.972	0.324	2 835.003

Multifactor analysis of syndrome differentiation in traditional Chinese medicine and clinical correlative factors in gastric cancer

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