中风证候动态研究现状与展望:数据与模型驱动模式的应用

doi:10.3736/jcim20111203

Abstract

Many clinical studies showed that the traditional Chinese medicine (TCM) syndromes in stroke have been dynamically changing since the onset of the disease. The changing of TCM syndromes can be attributed to multiple correlative factors such as age, sex, area distribution, underlying diseases, and constitutional factor. Data-driven methods involving multivariate statistical methods and descriptive approach have been used to analyze the regularity of dynamically changed TCM syndromes of stroke. However, expressing non-linear relationship between symptom or correlative factors and syndrome patterns by data-driven models is challenging. Model-driven methods involving artificial neural networks and Bayesian networks are new methods for studying the changes in TCM syndromes in patients with stroke. In this review, the authors summarized the studies of dynamically changed patterns of stroke syndromes based on data-driven methods and some clinical trials on TCM syndromes based on model-driven methods. Further studies are needed to improve the understanding of the dynamically changing regularity of TCM syndromes for stroke by using model-driven methods so as to develop appropriate and timely TCM treatments.

Key words: stroke, syndrome, data-driven, model-driven, artificial neural networks

Qin-hui Fu, Jian Pei, Jian-rong Hui, Yi Song . Studies on dynamic changes in traditional Chinese medicine syndrome patterns for stroke using data-driven and model-driven approaches: A review. Journal of Chinese Integrative Medicine, 2011, 9(12): 1292-1300.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20111203

http://www.jcimjournal.com/EN/Y2011/V9/I12/1292

[1]	Li S . Discussion on the characteristics of TCM syndromes from the concepts of dimensions and ranks: approaches to the standardization of TCM syndromes. Beijing Zhong Yi Yao Da Xue Xue Bao. 2003; 26(3): 1-4. Chinese with abstract in Englsih. doi: 10.3321/j.issn:1006-2157.2003.03.001
	李梢 . 从维度与阶度探讨中医证候的特征及标准化方法.北京中医药大学学报. 2003; 26(3):1-4. doi: 10.3321/j.issn:1006-2157.2003.03.001
[2]	Guo L, Wang YY, Zhang ZB . Interpretation of the concept of traditional Chinese medicine syndrome. Beijing Zhong Yi Yao Da Xue Xue Bao. 2003; 26(2): 5-8. Chinese. doi: 10.3321/j.issn:1006-2157.2003.02.002
	郭蕾, 王永炎, 张志斌 . 关于证候概念的诠释.北京中医药大学学报. 2003; 26(2):5-8. doi: 10.3321/j.issn:1006-2157.2003.02.002
[3]	Gao Y . Thinking about problems of constructing the clinical evaluation system for traditional Chinese medicine. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2006; 12 (4): 256-258. Chinese. doi: 10.3969/j.issn.1006-3250.2006.04.008
	髙颖 . 关于构建中医临床评价体系若干问题的思考.中国中医基础医学杂志. 2006; 12(4):256-258. doi: 10.3969/j.issn.1006-3250.2006.04.008
[4]	Li S . Computational systems biology-based TCM research: a case study of cold/hot Zheng and associated formula. Shi Jie Ke Xue Ji Shu Zhong Yi Yao Xian Dai Hua. 2007 ; 9(1) : 105-111. Chinese with abstract in English. doi: 10.11842/wst.2007.1.[sequence]
	李梢 . 中医药计算系统生物学与寒热证候研究.世界科学技术——中医药现代化. 2007; 9(1):105-111. doi: 10.11842/wst.2007.1.[sequence]
[5]	Jia N, Cai YF, Bai XX, Huang XP, Huang Y . Characteristics of traditional Chinese medicine syndromes in patients with onset acute ischemic stroke: a report of 118 cases. Xin Zhong Yi. 2008; 40(4): 63-64. Chinese. doi: 10.3969/j.issn.0256-7415.2008.04.034
	贾妮, 蔡业峰, 白小欣, 黄新培, 黄燕 . 118例急性缺血性中风病人始发证候特征的临床研究.新中医. 2008; 40(4) : 63-64. doi: 10.3969/j.issn.0256-7415.2008.04.034
[6]	Huang Y, Miao XL, Cai YF, Liang WX, Yang XB, Ma B, Gao Y . Analysis on the area difference of TCM syndromes in patients with acute ischemic stroke. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2008; 14 (3): 207-208. Chinese. doi: 10.3969/j.issn.1006-3250.2008.03.022
	黄燕, 缪晓路, 蔡业峰, 梁伟雄, 杨小波, 马斌, 髙颖 . 缺血性中风急性期证候不同地域差异性分析.中国中医基础医学杂志. 2008; 14(3):207-208. doi: 10.3969/j.issn.1006-3250.2008.03.022
[7]	Qi SW, Song JJ, Zhang DX, Zhang SW, Liu YX, Yang QL, Zhang BH . Research on relationship of stroke hemiplegia patients ⁵ personalities, TCM patterns and coping modes. Shi Jie Zhong Yi Yao. 2010 ; 5(3): 155-157. Chinese with abstract in English.
	齐斯文, 宋婧杰, 张德秀, 张胜伟, 刘羽犧, 杨秋莉, 张伯华 . 中风偏瘫患者的个性及应对方式与中医证型的相关性研究.世界中医药. 2010; 5(3):155-157.
[8]	Gao XL, Lin H . Study on correlation between risk factors and syndromes of traditional Chinese medicine in patients with acute ischemic stroke. Zhejiang Zhong Xi Yi Jie He Za Zhi. 2010; 20(10): 637-639. Chinese.
	髙雪亮, 林浩 . 急性缺血性中风危险因素与中医证候的相关性分析.浙江中西医结合杂志. 2010; 20(10):637-639.
[9]	Qin J, Zhang YK . Analysis on the law of TCM syndrome distribution among patients with ischemic stroke of different age groups. Henan Zhong Yi. 2007 ; 27(12): 37-38. Chinese. doi: 10.3969/j.issn.1003-5028.2007.12.021
	秦骥, 张运克 . 不同年龄组缺血性中风患者证候分布规律分析.河南中医. 2007; 27(12):37-38. doi: 10.3969/j.issn.1003-5028.2007.12.021
[10]	Liang WX, Lai SL, Liu MC, Mo CW, Huang PX, Wen ZH, Wang Q, Chen YB . Scoring of TCM syndromes in stroke and analysis of its correlative factors. Guangzhou Zhong Yi Yao Da Xue Xue Bao. 1999; 16(2): 81-84. Chinese with abstract in English. doi: 10.3969/j.issn.1007-3213.1999.02.001
	梁伟雄, 赖世隆, 刘茂才, 莫传伟, 黄培新, 温泽淮, 王奇, 陈云波 . 中风病中医证候与相关因素的分析.广州中医药大学学报. 1999; 16(2):81-84. doi: 10.3969/j.issn.1007-3213.1999.02.001
[11]	Liu Q, Chen ZG, Meng FX, Guo RJ, Han G, Lin C, Wang L, Ma LZ . Preliminary investigation of correlation between distributions of TCM syndromes and background diseases in acute stage of apoplexy. Zhonghua Zhong Yi Yao Za Zhi. 2008; 23(7) : 619-621. Chinese with abstract in English.
	刘强, 陈志刚, 孟繁兴, 郭荣娟, 韩刚, 林参, 王乐, 马丽珍 . 中风病急性期证候与基础病病史相互关系初探. 中华中医药杂志. 2008; 23(7):619-621.
[12]	Huang X, Fu WM . Research on the relationship between the TCM syndrome classifacation of ischemic stroke and blood lipid, blood pressure and hemorheology. Zhongguo Zhong Yi Ji Zheng. 2002 ; 11(1): 32-33. Chinese. doi: 10.3969/j.issn.1004-745X.2002.01.022
	黄晓, 符为民 . 缺血性中风(中经络)证候分类与血脂､血压､血液流变学关系的研究.中国中医急症. 2002; 11(1) : 32-33. doi: 10.3969/j.issn.1004-745X.2002.01.022
[13]	Huang Y, Guo JW, Zhang YT, Miao XL, Liu MC . Study on dynamic evolution of stroke syndromes. Xin Zhong Yi. 2005; 37(11): 79-80. Chinese.
	黄燕, 郭建文, 张燕婷, 缪晓路, 刘茂才 . 中风病证候动态演变规律研究.新中医. 2005; 37(11):79-80.
[14]	Li S . Conception and study on the biological molecules network symbol of TCM syndrome. Zhong Yi Za Zhi. 2009; 50(9): 773-776. Chinese. doi: 10.3969/j.issn.1674-3849.2007.01.025
	李梢 . 中医证候生物分子网络标志的构想与研究.中医杂志. 2009; 50(9):773-776. doi: 10.3969/j.issn.1674-3849.2007.01.025
[15]	Li KT, He HW, Wang ZJ, Zheng DT, Chen TJ . Study in NC code generating automatically based on data driving. Zu He Ji Chuang Yu Zi Dong Hua Jia Gong Ji Shu. 2001 ; ( 5): 20-24. Chinese with abstract in English.
	李克天, 何汉武, 王志坚, 郑德涛, 陈统坚 . 数据驱动的NC代码自动生成方法研究.组合机床与自动化加工技术. 2001; ( 5):20-24.
[16]	Group of Encephalopathy Emergency of State Administration of Traditional Chinese Medicine. Criteria for diagnosis and effect evaluation of stroke ( trial implementation) .Beijing Zhong Yi Yao Da Xue Xue Bao. 1996; 19(1) : 55-56. Chinese.
	国家中医药管理局脑病急症协作组. 中风病诊断与疗效评定标准(试行).北京中医药大学学报. 1996; 19(1) : 55-56.
[17]	Group for Studying Syndrome of Stroke and Clinical Diagnosis; Wang SD, Du MH, Xie QF, Jia ZX, Wang YY. Study on evolution rule of TCM syndromes of patients with acute ischemic stroke. Zhongguo Zhong Yi Ji Zheng. 1996; 5(3) : 121-124. Chinese.
	《中风病证候学与临床诊断的研究》研究组; 王顺道,杜梦华,解庆凡,贾滋欣,王永炎. 中风病急性期证候演变规律的研究.中国中医急症. 1996; 5(3):121-124.
[18]	Gao Y, Geng XJ, Zhu YP, Dong M, Li LJ, Xu X, Wang LF, Liu SH, Zhang JP . To explore the change rule of wind-phlegm syndrome of ischemic stroke. Zhonghua Zhong Yi Yao Xue Kan. 2010; 28(7) : 1399- 1401. Chinese with abstract in English.
	髙宇, 耿晓娟, 朱亚萍, 董梅, 李良军, 徐翔, 王凌飞, 刘淑红, 张军平 . 对缺血性中风“风痰”证变化规律的探讨.中华中医药学刊. 2010; 28(7):1399-1401.
[19]	Xie YZ, Ma HM, Cheng PR, Zhao ZW, Xu JF, Li HQ, Zou YH . Characteristics of different syndrome elements in different classification of OCSP in patients with acute ischemic stroke. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2008; 14(1): 44-45. Chinese. doi: 10.3969/j.issn.1006-3250.2008.01.021
	谢颖桢, 马洪明, 程平荣, 赵振武, 徐俊峰, 李焕芹, 邹忆怀 . 急性缺血性中风病不同OCSP分型证候要素的特征.中国中医基础医学杂志. 2008; 14(1):44-45. doi: 10.3969/j.issn.1006-3250.2008.01.021
[20]	Song Y, Pei J, Liu ZD, Li HY, Cai YF, Guo JW, Huang Y . Dynamic changes in traditional Chinese medicine syndromes in patients with ischemic stroke treated by acupuncture. J Chin Integr Med. 2009 ; 7 (4) : 334-341. Chinse with abstract in English. doi: 10.3736/jcim20090407
	宋毅, 裴建, 刘志丹, 李海燕, 蔡业峰, 郭建文, 黄燕 . 针刺干预缺血性中风病证候动态化及相关研究.中西医结学报. 2009; 7(4):334-341. doi: 10.3736/jcim20090407
[21]	Yang L, Huang Y, Cai YF, Du BX, Chen HX, Lu M, Huang PX . Research on the distribution and change rules of phlegm and stasis syndrome of 1 418 patients with stroke. Liaoning Zhong Yi Za Zhi. 2004; 31(6): 459-460. Chinese.
	杨利, 黄燕, 蔡业峰, 杜宝新, 陈红霞, 卢明, 黄培新 . 1418例中风患者痰瘀证候分布和演变规律探析.辽宁中医杂志. 2004; 31(6):459-460.
[22]	He G, Feng ZJ, Lu J, Jia TG, Yue LM, Liu Z, Song WJ, Yu HM, He H . Research and discussion on the distribution and dynamic changes of stroke syndrome. Zhongguo Zhong Yi Ji Zheng. 2007 ; 16(6): 686-687. Chinese. doi: 10.3969/j.issn.1004-745X.2007.06.031
	何刚, 冯子驹, 卢静, 贾天贵, 岳良明, 刘震, 宋维健, 于红梅, 何华 . 中风病证候分布及动态变化研究与探讨.中国中医急症. 2007; 16(6):686-687. doi: 10.3969/j.issn.1004-745X.2007.06.031
[23]	Wang SD, Si ZG, Huang YX, Du MH, Xie QF, Zhang XJ, Wang YX, Jia ZX, Liu ZX, Hu PL . Preliminary study on the traditional Chinese medicine syndrome of stroke. Zhongguo Zhong Yi Ji Zheng. 1995; 4(2) : 85-88. Chinese.
	王顺道, 司志国, 黄意兴, 杜梦华, 解庆凡, 张秀娟, 王一贤, 贾滋欣, 刘宗学, 胡沛林 . 中风病证候的初步研究.中国中医急症. 1995; 4(2):85-88.
[24]	You JS, Huang Y, Cai YF, Guo JW, Liang WX, Huang PX, Liu MC . Characteristics of traditional Chinese medicine syndromes in patients with acute ischemic stroke of yin or yang syndrome: a multicenter trial. J Chin Integr Med. 2008; 6(4): 346-351. Chinse with abstract in English.
	尤劲松, 黄燕, 蔡业峰, 郭建文, 梁伟雄, 黄培新, 刘茂才 . 缺血性中风急性期患者阴阳类证中医证候特点的多中心临床研究.中西医结合学报. 2008; 6(4):346-351.
[25]	Xu JF, Li BY, Gao Y, Hou ZS . Study on evolvement patterns of ischemic apoplexy syndromes. Tianjin Zhong Yi Yao. 2009; 26(6): 511-514. Chinese with abstract in English.
	徐俊峰, 李保洋, 髙颖, 侯忠生 . 缺血性中风病证候演变模式的研究.天津中医药. 2009; 26(6):511-514.
[26]	Xin XY, Zhang H, Gao Y . Dynamic evolutive rule of the phlegm-fire syndrome in acute ischemic stroke and the ralationship between neurological parafunction and different forms of evolution of the syndrome. Liaoning Zhong Yi Za Zhi. 2010; 37(9): 1644-1646. Chinese with abstract in Chinese.
	辛喜艳, 张华, 髙颖 . 缺血性中风急性期痰热证的证候演变特点及其与神经功能缺损程度的关系.辽宁中医杂志. 2010; 37(9):1644-1646.
[27]	Ma B, Gao Y . Preliminary study on the change rule of stroke syndrome elements on the 7th and 14th days of onset. Liaoning Zhong Yi Za Zhi. 2006; 33(12) : 1561-1563. Chinese.
	马斌, 髙颖 . 中风病发病第7天和第14天证候要素演变规律初步研究.辽宁中医杂志. 2006; 33(12):1561-1563.
[28]	Liu Q, Gao Y . Cluster analysis of TCM diagnostic data in different stages of ischemic stroke. Zhonghua Zhong Yi Yao Za Zhi. 2007; 22(3): 162-164. Chinese with abstract in English. doi: 10.3969/j.issn.1673-1727.2007.03.008
	刘强, 髙颖 . 中风病不同阶段四诊信息的指标聚类分析.中华中医药杂志. 2007; 22(3):162-164. doi: 10.3969/j.issn.1673-1727.2007.03.008
[29]	Zhang H, Gao Y . Correlation between syndrome changes and neurological parafunction of ischemia stroke. Beijing Zhong Yi Yao Da Xue Xue Bao. 2007 ; 30(4) : 275-278. Chinese with abstract in English. doi: 10.3321/j.issn:1006-2157.2007.04.017
	张华, 髙颍 . 缺血性中风证候演变与神经功能缺损的相关性研究.北京中医药大学学报. 2007; 30(4):275-278. doi: 10.3321/j.issn:1006-2157.2007.04.017
[30]	Xu JF, Gao Y, Wang ZH, Hou ZS, Liu C, Zhang YX . Study on the relationship between the TCM syndromes and neurological impairment of stroke. Zhong Yi Za Zhi. 2010 ; 51(6): 540-543. Chinese with abstract in English.
	徐俊峰, 髙颖, 王振华, 侯忠生, 刘超, 张严心 . 中风病证候与神经功能缺损程度的关系.中医杂志. 2010; 51(6) : 540-543.
[31]	Li JS, Yu XQ, Qing H, Wang YY . Analysis on quality of life of the patient with stroke and its influencing factors. Zhong Yi Za Zhi. 2005; 46(2): 113-115. Chinese with abstract in English.
	李建生, 余学庆, 庆慧, 王永炎 . 中风患者生存质量及其影响因素分析.中医杂志. 2005; 46(2):113-115.
[32]	Ai LX, Wang XP, Chen RH, Wang WT . Evaluation of different TCM syndrome type of stroke and study on its correlation to quality of life. Zhongguo Zhong Yi Ji Zheng. 2010; 19(7): 1141, 1166. Chinese. doi: 10.3969/j.issn.1004-745X.2010.07.036
	艾立新, 王希平, 陈荣浩, 王文同 .脑卒中中医证候分型测评与生存质量相关性研究 .中国中医急症. 2010; 19(7): 1141, 1166. doi: 10.3969/j.issn.1004-745X.2010.07.036
[33]	Hui JR, Pei J, Song Y, Fu QH, Hui JP . Overview of research and application of patient-reported outcomes in stroke. Shanghai Zhong Yi Yao Da Xue Xue Bao. 2009 ; 23(4) : 85-88. Chinese with abstract in English.
	惠建荣, 裴建, 宋毅, 傅勤慧, 惠建萍 . 中风病患者报告的临床结局评价研究与应用进展.上海中医药大学学报. 2009; 23(4):85-88.
[34]	Lai SL, Guo XF, Liang WX, Wen ZH, Wang Q, Lao YR . Preliminary study on outcome assessment system of treatment of stroke. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2004; 24(3): 197-201. Chinese with abstract in English.
	赖世隆, 郭新峰, 梁伟雄, 温泽淮, 王奇, 老膺荣 . 中风病疗效评价指标体系的初步研究.中国中西医结合杂志. 2004; 24(3) : 197-201.
[35]	Hu XJ, Zhang BL, Cai GX . Developing and evaluating of quality of life scale of stroke. Zhong Yi Yao Xue Kan. 2006; 24(9): 1638-1640. Chinese. doi: 10.3969/j.issn.1673-7717.2006.09.025
	胡学军, 张伯礼, 蔡光先 . 中风病患者生存质量量表的研制与考评.中医药学刊. 2006; 24(9):1638-1640. doi: 10.3969/j.issn.1673-7717.2006.09.025
[36]	Yuan SH, Wang TF . Problems in establishing TCM syndrome diagnosis model based on polybasic statistical method. Beijing Zhong Yi Yao Da Xue Xue Bao. 2004 ; 27(4): 9-11. Chinese. doi: 10.3321/j.issn:1006-2157.2004.04.004
	袁世宏, 王天芳 . 多元统计方法在建立证候诊断模型研究中存在问题的思考.北京中医药大学学报. 2004; 27(4):9-11. doi: 10.3321/j.issn:1006-2157.2004.04.004
[37]	Bai YJ, Shen HB, Meng QG, Wang YY . Complexity science-based development approach and strategy of Chinese medicine. Zhongguo Zhong Yi Yao Xin Xi Za Zhi. 2005; 12(1) : 2-5. Chinese.
	白云静, 申洪波, 孟庆刚, 王永炎 . 基于复杂性科学的中医学发展取向与方略.中国中医药信息杂志. 2005; 12(1):2-5.
[38]	Li S, Zhang XG, Ji L, Li YD . Bioinformatics strategies and methods of complex diseases. Shi Jie Hua Ren Xiao Hua Za Zhi. 2003; 11(10): 1465-1469. Chinese. doi: 10.3969/j.issn.1009-3079.2003.10.001
	李梢, 张学工, 季梁, 李衍达 . 复杂性疾病生物信息学研究的策略与方法.世界华人消化杂志. 2003; 11(10) : 1465-1469. doi: 10.3969/j.issn.1009-3079.2003.10.001
[39]	Guo L, Wang YY . Discussion on complex phenomena of TCM syndromes and the corresponding research ideas. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi. 2004; 10(2) : 3-5. Chinese. doi: 10.3969/j.issn.1006-3250.2004.02.002
	郭蕾, 王永炎 . 中医证候中的复杂现象及相应的研究思路.中国中医基础医学杂志. 2004; 10(2):3-5. doi: 10.3969/j.issn.1006-3250.2004.02.002
[40]	Zhu WF, Yan JF, Huang BQ . Application of Bayesian network in syndrome differentiation system of traditional Chinese medicine. J Chin Integr Med. 2006; 4(6): 567-570. Chinese with abstract in English.
	朱文锋, 晏峻峰, 黄碧群 . 贝叶斯网络在中医证素辨证体系中的应用.中西医结合学报. 2006; 4(6):567-570.
[41]	Qu M, Tang QS, Bao ZX, Wang Y, Ma L . Application of Bayesian network in research of TCM syndromes. Zhonghua Zhong Yi Yao Xue Kan. 2008; 26(7) : 1497-1498. Chinese.
	曲淼, 唐启盛, 包祖晓, 王耘, 马良 . 贝叶斯网络模型在中医证候研究中的应用.中华中医药学刊. 2008; 26(7):1497-1498.
[42]	Han LQ. Course in artificial neural networks. Beijing: Beijing University of Posts and Telecommunications Press. 2006 : 5. Chinese.
	韩力群 . 人工神经网络教程.北京: 北京邮电大学出版社. 2006: 5.
[43]	Bai YJ, Shen HB, Meng QG, Wang YY . Study on non-linear modeling of TCM syndrome based on neural network model. Zhongguo Zhong Yi Yao Xin Xi Za Zhi. 2007; 14(7): 3-4. Chinese. doi: 10.3969/j.issn.1005-5304.2007.07.002
	白云静, 申洪波, 孟庆刚, 王永炎 . 基于人工神经网络的中医证候非线性建模研究.中国中医药信息杂志. 2007; 14(7) : 3-4. doi: 10.3969/j.issn.1005-5304.2007.07.002
[44]	Tang QY, Feng MG. DPS data processing system for practical statistics. Beijing: Science Press. 2002. Chinese.
	唐启义, 冯明光 . 实用统计分析及其DPS数据处理系统.北京: 科学出版社. 2002.
[45]	Fan XP, Peng Z, Yang SY, Hu SY, Tang FY, Song WX . Study on depression classified system based on multilayer perceptrons artificial neural network. Ji Suan Ji Gong Chen Yu Ying Yong. 2004; 13(2): 205-208. Chinese with abstract in English.
	樊晓平, 彭展, 杨胜跃, 胡随瑜, 唐凤英, 宋炜熙 . 基于多层前馈型人工神经网络的抑郁症分类系统研究. 计算机工程与应用. 2004; 13(2):205-208.
[46]	Bai YJ, Meng QG, Shen HB, Wang YY . Study on non-linear modeling of TCM syndrome of DN based on developed BP neural network model. Beijing Zhong Yi Yao Da Xue Xue Bao. 2008; 31(5): 308-311. Chinese with abstract in English. doi: 10.3321/j.issn:1006-2157.2008.05.006
	白云静, 孟庆刚, 申洪波, 王永炎 . 基于改进的BP神经网络的糖尿病肾病中医证候非线性建模研究.北京中医药大学学报. 2008; 31(5):308-311. doi: 10.3321/j.issn:1006-2157.2008.05.006
[47]	Bai YJ, Shen HB, Meng QG . Study on BP neural network modeling of TCM syndrome of RA based on conjugate gradient descent algorithm. Zhongguo Zhong Yi Yao XinXiZaZhi. 2010; 17(3): 96-97. Chinese. doi: 10.3969/j.issn.1005-5304.2010.03.054
	白云静, 申洪波, 孟庆刚 . 基于共轭梯度下降算法的类风湿关节炎BP神经网络证候模型研究.中国中医药信息杂志. 2010; 17(3) : 96-97. doi: 10.3969/j.issn.1005-5304.2010.03.054
[48]	Ying J, Li ZX, Li S, Ji L, Liu DL, Ma WY . Collection and analysis of characteristics of tongue manifestations in patients with cerebrovascular diseases. Beijing Zhong Yi Yao Da Xue Xue Bao. 2005; 28(4) : 62-66. Chinese with abstract in English.
	英杰, 李重锡, 李梢, 季梁, 刘德麟, 马维娅 . 脑血管病患者舌象特征的提取与分析方法.北京中医药大学学报. 2005; 28(4):62-66.
[49]	Bai YJ, Shen HB, Meng QG, Wang YY . Discussion and analysis on the method of neural network model of TCM syndrome. Zhong Yi Yao Xue Kan. 2004 ; 22 (12): 2221-2223. Chinese. doi: 10.3969/j.issn.1673-7717.2004.12.029
	白云静, 申洪波, 孟庆刚, 王永炎 . 中医证候研究的人工神经网络方法探析.中医药学刊. 2004; 22(12):2221-2223. doi: 10.3969/j.issn.1673-7717.2004.12.029

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Studies on dynamic changes in traditional Chinese medicine syndrome patterns for stroke using data-driven and model-driven approaches: A review

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