解郁活血方对脑梗死后抑郁症患者神经功能康复的影响

doi:10.3736/jcim20040309

Abstract

Objective: To study the influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction. Methods: Fifty four patients suffered from the depression after acute cerebral infarction were randomly divided into three groups: depression control group, fluoxetine treated group and Jieyu Huoxue Decoction treated group. Eighteen patients of cerebral infarction without depression were enrolled in the no depression control group randomly. The Zung self-rating depression scale (SDS), the modified Edinburgh-Scandinavia stroke scale (MESSS) and the activities of daily living (ADL) were evaluated before treatment, 30 and 60 days after treatment. Results: After 30 and 60 days of treatment, SDS evaluation of the Jieyu Huoxue Decoction treated group showed significant difference as compared with the condition before treatment and that of the depression control group (P＜0.05 or P<0.01), MESSS evaluation and ADL evaluation also showed significant difference as compared with the condition before treatment and that of the depression control group (P＜0.05 or P<0.01); there was no obvious difference between the fluoxetine treated group and the Jieyu Huoxue Decoction treated group, but the Jieyu Huoxue Decoction treated group showed fewer symptoms and less side effect. Conclusion: Jieyu Huoxue Decoction can not only relieve depression after cerebral infarction, but also improve neurological functions.

Key words: Jieyu Huoxue Decoction, cerebral infarction, depression, rehabilitation

CLC Number:

R692

Bei-lei Feng, Qiao-chu Wang, Zheng-yuan Li. Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction. Journal of Chinese Integrative Medicine, 2004, 2(3): 182-184.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20040309

http://www.jcimjournal.com/EN/Y2004/V2/I3/182

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References 7

[1]	陈小江, 林志雄, 李君良 , 等. 抗抑郁药物对脑卒中后抑郁症及其神经功能康复疗效观察[J]. 中国临床康复, 2002,6(9):1289 doi: 10.3321/j.issn:1673-8225.2002.09.033
[2]	中华医学会. 脑血管病诊断和分类诊断要点——神经功能缺损程度的评分标准[J]. 中华神经科杂志, 1996,29(5):376-383
[3]	美国精神科学协会. 颜伟文译.精神障碍诊断和统计手册(第4版)[M]. 上海: 上海精神医学出版社, 1994,( 第4版):327-332
[4]	冯蓓蕾, 王翘楚, 顾丽芳 . 卒中后抑郁症研究现状[J]. 国外医学·脑血管疾病分册, 1999,7(1):14-16
[5]	Krishnan KR . Neuroanatomic substrates of depression in the elderly[J]. J Geriatr Psychiatry Neurol, 1993,6(1):39-58 doi: 10.1007/BF02191522 pmid: 8399409
[6]	Burvill P, Johnson G, Jamrozik K , et al. Risk factors for post-stroke depression[J]. Int J Geriatr Psychiatry, 1997,12(2):219-226 doi: 10.1002/(SICI)1099-1166(199702)12:23.0.CO;2-E pmid: 9097215
[7]	Andersen G, Vestergaard K, Ingeman-Nielsen MW , et al. Risk factors for depression after apoplexy[J]. Ugeskr Laeger, 1996,158(43):6107-6110 pmid: 8928298

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Group	n	Before treatment	30 d after treatment	60 d after treatment
No depression control	15	30.2±4.2	27.1±4.3	25.8±3.7
Depression control	16	48.8±5.7	43.5±5.2	41.1±4.7^△
Fluoxetine treated	16	48.1±6.13	6.9±4.3^▲▲	34.9±4.6^△▲▲
Jieyu Huoxue Decoction treated	17	48.2±5.83	5.9±4.1^▲▲	32.9±5.1^△▲▲

Group	n	Before treatment	30 d after treatment	60 d after treatment
No depression control	15	21.1±5.2	14.6±4.2^▲▲	9.4±4.2^△▲▲
Depression control	16	23.3±5.9	18.6±5.2	14.4±2.2^△
Fluoxetine treated	16	23.9±5.5	13.6±5.1^▲▲	9.1±3.2^△▲▲
Jieyu Huoxue Decoction treated	17	23.5±6.2	13.9±4.9^▲▲	9.3±5.2 ^△▲▲

Group	n	Before treatment	30 d after treatment	60 d after treatment
No depression control	15	25.4±3.5	21.8±2.6^▲▲	19.8±4.2^△▲▲
Depression control	16	29.9±2.9	25.8±3.2	23.8±4.2^△
Fluoxetine treated	16	28.9±3.6	20.8±5.1^▲▲	19.1±3.2^△▲▲
Jieyu Huoxue Decoction treated	17	28.5±4.5	20.3±4.2^▲▲	19.4±2.2^△▲▲

Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction

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