Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2004, Vol. 2 ›› Issue (3): 182-184.doi: 10.3736/jcim20040309

• Original Clinical Research • Previous Articles     Next Articles

Influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction

Bei-lei Feng1(), Qiao-chu Wang2, Zheng-yuan Li1   

  1. 1. Department of Neurology, Shanghai Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai 200082, China
    2. Department of Sleep Disorder, Shanghai Hospital of Traditional Chinese Medicine, Shanghai 200071, China
  • Online:2004-06-20 Published:2018-10-25

Objective: To study the influence of Jieyu Huoxue Decoction on rehabilitation of patients with depression after cerebral infarction. Methods: Fifty four patients suffered from the depression after acute cerebral infarction were randomly divided into three groups: depression control group, fluoxetine treated group and Jieyu Huoxue Decoction treated group. Eighteen patients of cerebral infarction without depression were enrolled in the no depression control group randomly. The Zung self-rating depression scale (SDS), the modified Edinburgh-Scandinavia stroke scale (MESSS) and the activities of daily living (ADL) were evaluated before treatment, 30 and 60 days after treatment. Results: After 30 and 60 days of treatment, SDS evaluation of the Jieyu Huoxue Decoction treated group showed significant difference as compared with the condition before treatment and that of the depression control group (P<0.05 or P<0.01), MESSS evaluation and ADL evaluation also showed significant difference as compared with the condition before treatment and that of the depression control group (P<0.05 or P<0.01); there was no obvious difference between the fluoxetine treated group and the Jieyu Huoxue Decoction treated group, but the Jieyu Huoxue Decoction treated group showed fewer symptoms and less side effect. Conclusion: Jieyu Huoxue Decoction can not only relieve depression after cerebral infarction, but also improve neurological functions.

Key words: Jieyu Huoxue Decoction, cerebral infarction, depression, rehabilitation

CLC Number: 

  • R692

Tab 1

Changes of SDS score after treatment (ヌ±S)"

Group n Before treatment 30 d after treatment 60 d after treatment
No depression control 15 30.2±4.2 27.1±4.3 25.8±3.7
Depression control 16 48.8±5.7 43.5±5.2 41.1±4.7
Fluoxetine treated 16 48.1±6.13 6.9±4.3▲▲ 34.9±4.6△▲▲
Jieyu Huoxue Decoction treated 17 48.2±5.83 5.9±4.1▲▲ 32.9±5.1△▲▲

Tab 2

Changes of MESSS score after treatment (ヌ±S)"

Group n Before treatment 30 d after treatment 60 d after treatment
No depression control 15 21.1±5.2 14.6±4.2▲▲ 9.4±4.2△▲▲
Depression control 16 23.3±5.9 18.6±5.2 14.4±2.2
Fluoxetine treated 16 23.9±5.5 13.6±5.1▲▲ 9.1±3.2△▲▲
Jieyu Huoxue Decoction treated 17 23.5±6.2 13.9±4.9▲▲ 9.3±5.2 △▲▲

Tab 3

Changes of ADL after treatment (ヌ±S)"

Group n Before treatment 30 d after treatment 60 d after treatment
No depression control 15 25.4±3.5 21.8±2.6▲▲ 19.8±4.2△▲▲
Depression control 16 29.9±2.9 25.8±3.2 23.8±4.2
Fluoxetine treated 16 28.9±3.6 20.8±5.1▲▲ 19.1±3.2△▲▲
Jieyu Huoxue Decoction treated 17 28.5±4.5 20.3±4.2▲▲ 19.4±2.2△▲▲
[1] 陈小江, 林志雄, 李君良 , 等. 抗抑郁药物对脑卒中后抑郁症及其神经功能康复疗效观察[J]. 中国临床康复, 2002,6(9):1289
doi: 10.3321/j.issn:1673-8225.2002.09.033
[2] 中华医学会. 脑血管病诊断和分类诊断要点——神经功能缺损程度的评分标准[J]. 中华神经科杂志, 1996,29(5):376-383
[3] 美国精神科学协会. 颜伟文译.精神障碍诊断和统计手册(第4版)[M]. 上海: 上海精神医学出版社, 1994,( 第4版):327-332
[4] 冯蓓蕾, 王翘楚, 顾丽芳 . 卒中后抑郁症研究现状[J]. 国外医学·脑血管疾病分册, 1999,7(1):14-16
[5] Krishnan KR . Neuroanatomic substrates of depression in the elderly[J]. J Geriatr Psychiatry Neurol, 1993,6(1):39-58
doi: 10.1007/BF02191522 pmid: 8399409
[6] Burvill P, Johnson G, Jamrozik K , et al. Risk factors for post-stroke depression[J]. Int J Geriatr Psychiatry, 1997,12(2):219-226
doi: 10.1002/(SICI)1099-1166(199702)12:23.0.CO;2-E pmid: 9097215
[7] Andersen G, Vestergaard K, Ingeman-Nielsen MW , et al. Risk factors for depression after apoplexy[J]. Ugeskr Laeger, 1996,158(43):6107-6110
pmid: 8928298
[1] Ming-min Xu, Pei Guo, Qing-yu Ma, Xuan Zhou, Yu-long Wei, Lu Wang, Yue Chen, Yu Guo. Can acupuncture enhance therapeutic effectiveness of antidepressants and reduce adverse drug reactions in patients with depression? A systematic review and meta-analysis. Journal of Integrative Medicine, 2022, 20(4): 305-320.
[2] Tara Rajendran, Martha Summa-Chadwick. The scope and potential of music therapy in stroke rehabilitation. Journal of Integrative Medicine, 2022, 20(4): 284-287.
[3] Samwel Sylvester Msigwa, Yan Li, Xiang-lin Cheng, Fen Cao. Combining electroacupuncture and transcranial direct current stimulation as an adjuvant therapy enhances spontaneous conversation and naming in subacute vascular aphasia: A retrospective analysis. Journal of Integrative Medicine, 2022, 20(3): 244-251.
[4] Si-chun Gu, Jie Zhou, Qing Ye, Can-xing Yuan. Pingchan granule for depressive symptoms in Parkinson’s disease: A randomized, double-blind, placebo-controlled trial. Journal of Integrative Medicine, 2021, 19(2): 120-128.
[5] Leandro Lucena, Cristina Frange, Ana Claudia Amorim Pinto, Monica Levy Andersen, Sergio Tufik, Helena Hachul. Mindfulness interventions during pregnancy: A narrative review. Journal of Integrative Medicine, 2020, 18(6): 470-477.
[6] Toktam Sadat Firoozeei, Majid Barekatain, Mehrdad Karimi, Arman Zargaran, Shahin Akhondzadeh, Hossein Rezaeizadeh. Lavender and dodder combined herbal syrup versus citalopram in major depressive disorder with anxious distress: A double-blind randomized trial. Journal of Integrative Medicine, 2020, 18(5): 409-415.
[7] Nathalia Gomes Ribeiro de Moura, Ivan Cordovil, Arthurde Sá Ferreira. Traditional Chinese medicine wrist pulse-taking is associated with pulse waveform analysis and hemodynamics in hypertension. Journal of Integrative Medicine, 2016, 14(2): 100-113.
[8] Bosch Peggy, van den Noort Maurits, Yeo Sujung, Lim Sabina, Coenen Anton, van Luijtelaar Gilles. The effect of acupuncture on mood and working memory in patients with depression and schizophrenia. Journal of Integrative Medicine, 2015, 13(6): 380-390.
[9] Arthur de Sá Ferreira, Antonio Guilherme Pacheco. SimTCM: A human patient simulator with application to diagnostic accuracy studies of Chinese medicine. Journal of Integrative Medicine, 2015, 13(1): 9-19.
[10] Sheng Wei, Jin-liang Hou, Yu-bin Chao, Xi-yang Du, Shao-bo Zong . Analysis on content of serum monoamine neurotransmitters in macaques with anger-in-induced premenstrual syndrome and liver-qi depression syndrome. Journal of Chinese Integrative Medicine, 2012, 10(8): 925-931.
[11] David Sibbritt, Pamela van der Riet, Saowapa Dedkhard, Kannapatch Srithong. Rehabilitation of stroke patients using traditional Thai massage, herbal treatments and physical therapies. Journal of Chinese Integrative Medicine, 2012, 10(7): 743-750.
[12] Li Xiao-hong, Li Jing-jing, Liu Yue-yun, Chen Jia-xu. Central neurobiological mechanism of liver depression and spleen deficiency syndrome based on chronic stress: a review. Journal of Chinese Integrative Medicine, 2012, 10(1): 1-6.
[13] Sui Yue Hu, Su E Wang, Chun Hu Zhang. Relationship between symptom stratification and syndrome differentiation of traditional Chinese medicine for depressive episode. Journal of Chinese Integrative Medicine, 2011, 9(9): 933-936.
[14] Yuan-hong Xu , Jun-hua Wang, Hai-feng Li , Xiao-hu Zhu, Gang Wang. Efficacy of integrative respiratory rehabilitation training in exercise ability and quality of life of patients with chronic obstructive pulmonary disease in stable phase: A randomized controlled trial. Journal of Chinese Integrative Medicine, 2010, 8(5): 432-437.
[15] Hui Han, Li-min Wu, Wen-ming Yang, Mei-xia Wang, Jing-jing Tang, Han Wang, Zhi-xiu Liu, Rong-zhi Liu, Ting Dong, Juan Zhang , Bo Yang, Ming-xiang Han. Characteristics of traditional Chinese medicine syndromes in post-stroke depression. Journal of Chinese Integrative Medicine, 2010, 8(5): 427-431.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Jin-rong Fu. Establishment of multivariate diagnosis and treatment system of modern gynecology of traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 22-24
[2] Hao Li, Ming-jiang Yao, Wen-ming Zhao, Jie Guan, Lin-lin Cai, Ling Cui. A randomized, controlled, double-blind trial of Huannao Yicong capsule in senile patients with mild cognitive impairment. Journal of Chinese Integrative Medicine, 2008, 6(1): 25-31
[3] Zhi-chun Jin. Problems in establishing clinical guideline for integrated traditional Chinese and Western medicine. Journal of Chinese Integrative Medicine, 2008, 6(1): 5-8
[4] SUN Ming-yu, ZUO Jian, DUAN Ji-feng, HAN Jun, FAN Shi-ming, ZHANG Wei, ZHU Li-fang, YAO Ming-hui. Antitumor activities of kushen flavonoids in vivo and in vitro. Journal of Chinese Integrative Medicine, 2008, 6(1): 51-59
[5] Min Cheng, Qiong Feng, Shu-wen Qian, Hui Gao, Cui-qing Zhu. Preliminary assay of p-amyloid binding elements in heart-beneficial recipe. Journal of Chinese Integrative Medicine, 2008, 6(1): 68-72
[6] Ning-qun Wang, Liang-duo Jiang, Zong-xing Li. Research progress in asthma-related quality of life. Journal of Chinese Integrative Medicine, 2008, 6(1): 93-97
[7] Jing-yuan Mao, Chang-xiao Liu, Heng-he Wang, Guang-li Wei , Zhen-peng Zhang, Jie Xing, Wang Xian liang , Ying-fei Bi . Effects of Shenmai Injection on serum concentration and pharmacokinetics of digoxin in dogs with heart failure. Journal of Chinese Integrative Medicine, 2010, 8(11): 1070-1074
[8] Zhi-mei Wang, Bin Zhang. A study on translation of ellipses in Huangdi Neijing from perspective of hermeneutic theory. Journal of Chinese Integrative Medicine, 2010, 8(11): 1097-1100
[9] Gui Yu, Jie Wang. Thinking on building the network cardiovasology of Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(11): 1206-1210
[10] Pedro Saganha João, Doenitz Christoph, Greten Tobias, Efferth Thomas, J. Greten Henry. Qigong therapy for physiotherapists suffering from burnout: a preliminary study. Journal of Chinese Integrative Medicine, 2012, 10(11): 1233-1239