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Journal of Integrative Medicine ›› 2015, Vol. 13 ›› Issue (2): 65-68.doi: 10.1016/S2095-4964(15)60170-4

• Commentary •     Next Articles

The methodology flaws in Hinman’s acupuncture clinical trial, Part I: Design and results interpretation

Arthur Yin Fan   

  1. McLean Center for Complementary and Alternative Medicine, PLC., Vienna, VA 22182, USA
  • Received:2015-02-20 Accepted:2015-03-05 Online:2015-03-10 Published:2015-03-15

Key words: Acupuncture, Arthralgia, Chronic knee pain, Hinman, Zelen design, Clinical trial, Statistics, Flaws

[1] Hinman RS, McCrory P, Pirotta M, Relf I, Forbes A, Crossley KM, Williamson E, Kyriakides M, Novy K, Metcalf BR, Harris A, Reddy P, Conaghan PG, Bennell KL . Acupuncture for chronic knee pain: a randomized clinical trial. JAMA, 2014,312(13):1313-1322
doi: 10.1136/acupmed-2014-010727
[2] Berman BM, Lao L, Langenberg P, Lee WL, Gilpin AM, Hochberg MC . Effectiveness of acupuncture as adjunctive therapy in osteoarthritis of the knee: a randomized, controlled trial. Ann Intern Med, 2004,141(12):901-910
doi: 10.7326/0003-4819-141-12-200412210-00006
[3] Vickers AJ, Linde K . Acupuncture for chronic pain. JAMA, 2014,311(9):955-956
doi: 10.1001/jama.2013.285478
[4] Lao L, Yeung WF . Treating chronic knee pain with acupuncture. JAMA, 2015,313(6):627-628
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[5] Li YM . Treating chronic knee pain with acupuncture. JAMA, 2015,313(6):628
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[6] Hinman RS, McCrory P, Pirotta M, Relf I, Crossley KM, Reddy P, Forbes A, Harris A, Metcalf BR, Kyriakides M, Novy K, Bennell KL . Efficacy of acupuncture for chronic knee pain: protocol for a randomized controlled trial using a Zelen design. BMC Complement Altern Med, 2012, 12: 161
doi: 10.1186/1472-6882-12-S1-P161
[7] Australia New Zealand Clinical Trials Registry. Acupuncture for chronic knee pain trial [registry identifier: ACTRN12609001001280].[2015-02-22]. .
[8] Consort Transparent Reporting of Trials. Consort 2010: Trial design.[ 2015-03-09]. .
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[10] West A, Spring B. Randomized controlled trials.[ 2015-03-09].
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