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Journal of Integrative Medicine ›› 2015, Vol. 13 ›› Issue (5): 319-325.doi: 10.1016/S2095-4964(15)60196-0

• Research Article • Previous Articles     Next Articles

Complementary and alternative medicine use in Iranian patients with diabetes mellitus

Mohammad Hashem Hashempura,b, Mojtaba Heydaric, Seyed Hamdollah Mosavatc,d, Seyyed Taghi Heydarie, Mesbah Shamsf   

  1. a Noncommunicable Diseases Research Center, Fasa University of Medical Sciences, Fasa, Iran
    b Department of Traditional Medicine, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran
    c Research Center for Traditional Medicine and History of Medicine, Department of Traditional Persian Medicine, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
    d Essence of Parsiyan Wisdom Institute, Traditional Medicine and Medicinal Plant Incubator, Shiraz University of Medical Sciences, Shiraz, Iran
    e Health Policy Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
    f Endocrine and Metabolism Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran
  • Received:2015-04-28 Accepted:2015-06-16 Online:2015-09-10 Published:2015-09-15

Objective
There is increasing interest in complementary and alternative medicine generally, and especially by those affected by chronic diseases, such as diabetes mellitus. We aimed to determine the prevalence and pattern of complementary and alternative medicine use among patients suffering from diabetes mellitus in Shiraz, southern Iran. Another objective was to explore associated factors for use of complementary and alternative medicine among patients with diabetes mellitus.
Methods
A 19-item semi-structured questionnaire (open- and close-ended) was administered to 239 patients with diabetes mellitus in this cross-sectional study. It was carried out in two outpatient diabetes clinics affiliated with the Shiraz University of Medical Sciences, Shiraz, Iran.
Results
One hundred and eighty patients (75.3%) used at least one type of complementary and alternative medicine in the last year prior to the interview. Patients with diabetes mellitus who were living in a large family (≥ 5 members), not taking insulin, and believed that complementary and alternative medicine have synergistic effects with conventional medicine, were independently and significantly (Pvalues: 0.02, 0.04, and 0.01, respectively) more likely to use complementary and alternative medicine. Most of the users (97.7%) reported use of herbal preparations, and 89.4% of users did not change their medication, neither in medication schedule nor its dosage.
Conclusion
The use of complementary and alternative medicine, especially herbal remedies, is popular among diabetes patients in Shiraz, Iran. This use is associated with patients’ family size, type of conventional medications and their view about concomitant use of complementary and conventional medicine.

Key words: Diabetes mellitus, Complementary therapies, Prevalence, Medicine, Herbal, Iran

[1] International Diabetes Federation. IDF diabetes atlas. 6th ed. Brussels, Belgium: International Diabetes Federation. 2013.
[2] Dunning T . Complementary therapies and diabetes. Complement Ther Nurs Midwifery, 2003,9(2):74-80
doi: 10.1016/S1353-6117(02)00143-9
[3] Shrivastava SR, Shrivastava PS, Ramasamy J . Role of self-care in management of diabetes mellitus. J Diabetes Metab Disord, 2013,12(1):14
doi: 10.1186/2251-6581-12-14 pmid: 3599009
[4] Keskin A, Bilge U . Mental disorders frequency alternative and complementary medicine usage among patients with hypertension and type 2 diabetes mellitus. Niger J Clin Pract, 2014,17(6):717-722
doi: 10.4103/1119-3077.144384
[5] Hashempur MH, Homayouni K, Ashraf A, Salehi A, Taghizadeh M, Heydari M . Effect of Linum usitatissimum L.(linseed) oil on mild and moderate carpal tunnel syndrome: a randomized, double-blind, placebo-controlled clinical trial. Daru, 2014,22: 43
doi: 10.1186/2008-2231-22-43
[6] Bhalerao MS, Bolshete PM, Swar BD, Bangera TA, Kolhe VR, Tambe MJ, Wade MP, Bhowate SD, Sonje UB, Gogtay NJ, Thatte UM . Use of and satisfaction with complementary and alternative medicine in four chronic diseases: a cross-sectional study from India. Natl Med J India, 2013,26(2):75-78
[7] Mollaoglu M, Aciyurt A . Use of complementary and alternative medicine among patients with chronic diseases. Acta Clin Croat, 2013,52(2):181-188
[8] Akilen R, Pimlott Z, Tsiami A, Robinson N . The use of complementary and alternative medicine by individuals with features of metabolic syndrome. J Integr Med, 2014,12(3):171-174
doi: 10.1016/S2095-4964(14)60012-1
[9] Kashani L, Hassanzadeh E, Mirzabeighi A, Akhondzadeh S . Knowledge, attitude and practice of herbal remedies in a group of infertile couples. Acta Med Iran, 2013,51(3):189-194
pmid: 23605605
[10] Fahimi F, Hrgovic I, El-Safadi S, Munstedt K . Complementary and alternative medicine in obstetrics: a survey from Iran. Arch Gynecol Obstet, 2011,284(2):361-364
doi: 10.1007/s00404-010-1641-8 pmid: 20730543
[11] Harirchian MH, Sahraian MA, Hosseinkhani A, Amirzargar N . Level of attitude toward complementary and alternative medicine among Iranian patients with multiple sclerosis. Iran J Neurol, 2014,13(1):13-18
[12] Tonekaboni SH, Jafari Naeini S, Khajeh A, Yaghini O, Ghazavi A, Abdollah Gorji F . Use of complementary and alternative medicine for epileptic children in Tehran: a cross-sectional study(2009-2011). Iran J Child Neurol, 2014,8(1):26-31
[13] Asadi-Pooya AA, Emami M . Perception and use of complementary and alternative medicine among children and adults with epilepsy: the importance of the decision makers. Acta Med Iran, 2014,52(2):153-157
[14] Montazeri A, Sajadian A, Ebrahimi M, Haghighat S, Harirchi I . Factors predicting the use of complementary and alternative therapies among cancer patients in Iran. Eur J Cancer Care (Engl), 2007,16(2):144-149
doi: 10.1111/ecc.2007.16.issue-2
[15] Yekta Z, Zamani A, Mehdizade M, Farajzadegan Z . Pattern of complementary and alternative medicine use in urban population. J Res Health Sci, 2007,7(1):24-31
pmid: 23343868
[16] Montazeri A, Sajadian A, Ebrahimi M, Akbari ME . Depression and the use of complementary medicine among breast cancer patients. Support Care Cancer, 2005,13(5):339-342
doi: 10.1007/s00520-004-0709-z pmid: 15549425
[17] Roozbeh J, Hashempur MH, Heydari M . Use of herbal remedies among patients undergoing hemodialysis. Iran J Kidney Dis, 2013,7(6):492-495
doi: 10.5414/CN107431 pmid: 24241097
[18] Sattari M, Dilmaghanizadeh M, Hamishehkar H, Mashayekhi SO . Self-reported use and attitudes regarding herbal medicine safety during pregnancy in Iran. Jundishapur J Nat Pharm Prod, 2012,7(2):45-49
doi: 10.5812/jjpharma.3416 pmid: 24624153
[19] Hashem Dabaghian F, Abdollahi Fard M, Shojaei A, Kianbakht S, Zafarghandi N, Goushegir A . Use and attitude on herbal medicine in a group of pregnant women in Tehran. J Med Plants, 2012,11(41):22-33
[20] Tabatabaee M . Use of herbal medicine among pregnant women referring to Valiasr Hospital in Kazeroon, Fars, South of Iran. J Med Plants, 2011,10(37):96-108
[21] Saydah SH, Eberhardt MS . Use of complementary and alternative medicine among adults with chronic diseases: United States 2002. J Altern Complement Med, 2006,12(8):805-812
doi: 10.1089/acm.2006.12.805
[22] Chang HY, Wallis M, Tiralongo E . Use of complementary and alternative medicine among people living with diabetes: literature review. J Adv Nurs, 2007,58(4):307-319
[23] Bell RA, Suerken CK, Grzywacz JG, Lang W, Quandt SA, Arcury TA . Complementary and alternative medicine use among adults with diabetes in the United States. Altern Ther Health Med, 2006,12(5):16-22
doi: 10.1016/j.jep.2006.03.031 pmid: 17017751
[24] Shojaii A, Dabaghian FH, Goushegir A, Fard MA . Antidiabetic plants of Iran. Acta Med Iran, 2011,49(10):637-642
pmid: 22071637
[25] Zarshenas MM, Khademian S, Moein M . Diabetes and related remedies in medieval Persian medicine. Indian J Endocrinol Metab, 2014,18(2):142-149
doi: 10.4103/2230-8210.129103 pmid: 3987262
[26] Rashidi AA, Mirhashemi SM, Taghizadeh M, Sarkhail P . Iranian medicinal plants for diabetes mellitus: a systematic review. Pak J Biol Sci, 2013,16(9):401-411
doi: 10.3923/pjbs.2013.401.411 pmid: 24498803
[27] Heydari M, Homayouni K, Hashempur MH, Shams M . Topical Citrullus colocynthis in painful diabetic neuropathy: a double-blind randomized placebo-controlled clinical trial. J Diabetes. 2015 Mar 20.
[28] Yeh GY, Eisenberg DM, Kaptchuk TJ, Phillips RS . Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care, 2003,26(4):1277-1294
doi: 10.2337/diacare.26.4.1277 pmid: 12663610
[29] Ching SM, Zakaria ZA, Paimin F, Jalalian M. Complementary alternative medicine use among patients with type 2 diabetes mellitus in the primary care setting: a cross-sectional study in Malaysia. BMC Complement Altern Med, 2013,13: 148
doi: 10.1186/1472-6882-13-148
[30] Ceylan S, Hamzaoğlu O, Kömürcü S, Beyan C, Yalçin A . Survey of the use of complementary and alternative medicine among Turkish cancer patients. Complement Ther Med, 2002,10(2):94-99
doi: 10.1054/ctim.2002.0527
[31] Barner JC, Bohman TM, Brown CM, Richards KM . Use of complementary and alternative medicine for treatment among African-Americans: a multivariate analysis. Res Social Adm Pharm, 2010,6(3):196-208
doi: 10.1016/j.sapharm.2009.08.001
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