Osteoarthritis,Knee,Acupuncture point injection,Placental extracts,Pain,Swelling,Productive time," /> Osteoarthritis,Knee,Acupuncture point injection,Placental extracts,Pain,Swelling,Productive time,"/> Therapeutic effect of acupuncture point injection with placental extract in knee osteoarthritis
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Journal of Integrative Medicine ›› 2017, Vol. 15 ›› Issue (2): 135-141.doi: 10.1016/S2095-4964(17)60316-9

Special Issue: Acupuncture & Moxibustion

• Research Article • Previous Articles     Next Articles

Therapeutic effect of acupuncture point injection with placental extract in knee osteoarthritis

Kyeong Mee Parka, Tae Hwan Chob   

  1. a Inno Oriental Clinic, Daejon 34014, South Korea 
    b Cho Orthopaedic Clinic, Seoul 06643, South Korea
  • Received:2016-09-28 Accepted:2016-11-14 Online:2017-03-15 Published:2017-03-15
  • Contact: Kyeong Mee Park; E-mail: kmpark02@empas.com


This study evaluated the effectiveness of acupuncture point injection (API) with placental extract on pain reduction and joint function in patients with knee osteoarthritis (OA).


Fifty-two patients with knee OA, with an average age of 64, and having a symptom duration of more than 3 months were studied in this report. Placental extract was injected weekly into acupuncture point ST35, BL23, BL24 and BL25 for 5 weeks; 8 mL of placental extract into ST35 on the affected side, and 1 mL of placental extract to BL23, BL24 and BL25 bilaterally.


After a five-week treatment of API with placental extract, pain was substantially decreased in patients of all Kellgren-Lawrence (KL) grades. Improvement of knee joint swelling was also apparent. Decrease of pain and joint swelling improved daily working productive time among patients of all KL grades.


Study results imply that API with placental extract is a potentially useful therapy to control pain and maintain joint functions in knee OA patients.

Key words: Osteoarthritis, Knee, Acupuncture point injection, Placental extracts, Pain, Swelling, Productive time

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