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Journal of Chinese Integrative Medicine ›› 2006, Vol. 4 ›› Issue (2): 117-119.doi: 10.3736/jcim20060203

Special Issue: Traditional Chinese Medicine

• Editorial • Previous Articles     Next Articles

Methodological thoughts about research of standardized clinical protocols of traditional Chinese medicine

Ai-ping Lv1, Qing-lin Zha2, Zhi-bin Zhang3   

  1. 1. Institute of Basic Theory, China Academy of Traditional Chinese Medicine, Beijing 100700, China
    2. National Center of Pharmaceutical Engineering Research, Jiangxi College of Traditional Chinese Medicine, Nanchang, Jiangxi Province 330006, China
    3. History and Philology Institute of Traditional Chinese Medicine, China Academy of Traditional Chinese Medicine, Beijing 100700, China
  • Online:2006-03-20 Published:2006-03-15

The treatment of tradit ional Chinese medicine ( TCM) has been proved effective in clinical practice for thousands of years. To standardize the clinical protocols of TCM is absolutely necessary for enhancing the research quality of TCM and expanding the international influence of TCM. The standardization research on clinical protocols of TCM should be based on the basic theory of TCM and in the light of good clinical practice (GCP) principles. The clinical criteria for both diagnosis and efficacy evaluation of disease are also needed. To include all symptoms, tongue manifestations and pulse presentations into case report form, and to compare the differences in these clinical parameters between effective and non-effective cases by multivariate analysis may be helpful to find more specific indications for therapeutic protocol of TCM. Furthermore, It is suggested that two or more clinical trials on one therapeutic protocol are needed to identify its accurate indications.

Key words: Therapeutics (TCM), Benchmarking, Clinical protocols

CLC Number: 

  • R242
[1] 吕爱平 . 中药现代化发展新要求——应重视中药适应症和中药药效评价的研究[J]. 首都医药, 2003,10(3):27-30
doi: 10.3969/j.issn.1005-8257.2003.03.017
[2] 吕爱平, 李捎, 王永炎 . 从主观症状的客观规律探索中医证候分类的科学基础[J]. 中医杂志, 2005,46(1):4-6
[3] Li S, Lu AP, Zhang L , et al. Anti-Helicobacter pylori immunoglobulin G(IgG) and IgA antibody responses and the value of clinical presentations in diagnosis of H. pylori infection in patients with precancerous lesions[J]. World J Gastroenterol, 2003,9(4):755-758
[4] Lu AP, Zhang SS, Zha QL , et al. Correlation between the CD4, CD8 cell infiltration in gastric mucosa, Helicobacter pylori infection and symptoms in patients with chronic gastritis[J]. World J Gastroenterol, 2005,11(16):2486-2490
[5] 吕爱平, 陈可冀 . 疾病的证候分类研究思路[J]. 中国中西医结合杂志, 2005,25(9):843-845
doi: 10.7661/CJIM.2005.9.843
[6] 查青林, 林色奇, 吕爱平 . 多元统计分析在中医证候研究中的应用探析[J]. 江西中医学院学报, 2004,16(6):79-80
doi: 10.3969/j.issn.1005-9431.2004.06.037
[7] 何羿婷, 查青林, 闫小萍 , 等. 类风湿性关节炎主观症状因子分析及其与疗效的关系[J]. 中国中西医结合杂志, 2005,25(12):1076-1081
[8] 吕爱平, 何羿婷, 查青林 , 等. 类风湿性关节炎症状与疗效关系的回归分析[J]. 中西医结合学报, 2005,3(6):432-437
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