Search JIM Advanced Search

Journal of Chinese Integrative Medicine ›› 2007, Vol. 5 ›› Issue (2): 122-125.doi: 10.3736/jcim20070203

Special Issue: Traditional Chinese Medicine

• Commentary • Previous Articles     Next Articles

Breast cancer pathogenesis of stagnation of phlegm, poison and blood stasis: rationale and clinical application in traditional Chinese medicine

Sheng Liu1, Yong-qiang Hua1, Zhen-ping Sun1, Song Tan2, De-ming Lu1   

  1. 1. Department of Breast Surgery, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China
    2. Department of Oncology, Yantai Hospital of Traditional Chinese Medicine, Yantai, Shandong Province 265705, China
  • Online:2007-03-31 Published:2007-03-15

Breast cancer is called ''Ruyan'' in literature of traditional Chinese medicine. We synthesized the ancient and contemporary discussions and raised the theory that ''Duxie'' (poisonous pathogenic factor) is the etiological factor and pathologic product through the whole course of breast cancer. ''Liuyin Fudu'' (latent poison of six exogenous pathogenic factors) and ''Qiqing Yudu'' (stagnant poison of seven emotions) are the main etiological factors affecting the breast cancer occurrence. ''Aidu Neisheng'' (internal product of cancer poison) is the essential change in breast cancer occurrence. ''Tandu Yujie'' (stagnation of phlegm, poison and blood stasis) is the essential pathogenesis of the breast cancer's development. ''Yudu Weiqing'' (vestigial poison) is the main pathogenesis of breast cancer after operation. ''Yudu Pangcuan'' (vestigial poison invasion elsewhere) is the key pathogenesis of recurrence and metastasis after operation. ''Sanjie Jiedu'' (dispersing accumulation and detoxification) is an important therapeutic principle in breast cancer's treatment after operation. The ''Tandu-Yujie'' pathogenesis theory and ''Sanjie Jiedu'' therapeutic principle developed the theory about breast cancer in traditional Chinese medicine, and have some clinical application value.

Key words: breast cancer, pathogenesis, traditional Chinese medicine

CLC Number: 

  • R226
[1] 姜良铎, 张文生 . 从毒论治初探[J]. 北京中医药大学学报, 1998,21(5):2-3
Jiang LD, Zhang WS . Discussion of treatment based on poisonous pathogenic factors[J]. Beijing Zhong Yi Yao Da Xue Xue Bao, 1998,21(5):2-3
[2] 王文萍, 姜良铎, 刘明 . 肿瘤转移“痰毒流注”病机假说的研究思路[J]. 辽宁中医杂志, 2002,29(3):137-138
Wang WP, Jiang LD, Liu M . Research methods of ''Tandu Liuzhu'' pathogenesis hypojournal in tumor metastasis[J]. Liaoning Zhong Yi Za Zhi, 2002,29(3):137-138
[3] 张健, 张淑贤, 王沛 . 中医传舍理论与肿瘤转移[J]. 中国中医基础医学杂志, 1999,5(6):4-6
Zhang J, Zhang SX, Wang P . The traditional Chinese medicine doctrine of ''Chuanshe'' and tumor metastasis[J]. Zhongguo Zhong Yi Ji Chu Yi Xue Za Zhi, 1999,5(6):4-6
[4] 李俊玉 . 癌毒的病因病机及临证治法的概念探析[J]. 江西中医药, 2005,36(8):14-15
Li JY . Discussion on the ''Aidu'' definition of etiopathogenesis and pathogenesis and its treatment in clinical practice[J]. Jiangxi Zhong Yi Yao, 2005,36(8):14-15
[5] 吴雪卿, 阙华发, 何春梅 . 陆德铭教授治疗乳腺癌远处转移37例[J]. 上海中医药大学学报, 2000,14(1):24-26
Wu XQ, Que HF, He CM . 37 cases of remote metastasis of mammary carcinoma treated by Prof. Lu De-ming[J]. Shanghai Zhong Yi Yao Da Xue Xue Bao, 2000,14(1):24-26
[6] 陈前军, 司徒红林, 周劬志 , 等. 乳宁Ⅱ号抗乳腺癌短期复发转移的临床研究[J]. 现代中西医结合杂志, 2002,11(16):1546-1548
Cheng QJ, Situ HL, Zhou QZ , et al. Clinical research on prevention of short-term recidivation and metastasis of breast cancer by Runing Ⅱ[J]. Xian Dai Zhong Xi Yi Jie He Za Zhi, 2002,11(16):1546-1548
[7] 赵连臣, 贾喜花, 唐汉钧 . 乳宁Ⅱ号对乳腺癌术后患者生活质量影响的临床观察[J]. 中医药学刊, 2006,24(5):956-957
Zhao LC, Jia XH, Tang HJ . Clinical observation on life quality of the patients treated by Runing Ⅱ after operation of mammary cancer[J]. Zhong Yi Yao Xue Kan, 2006,24(5):956-957
[8] 秦海洸 . 唐汉钧教授治疗乳腺癌辨证思路与用药经验[J]. 中西医结合学报, 2004,2(4):297-298
Qin HG . Professor Tang Han-jun's thinking in syndrome differentiation and experience in treating breast cancer[J]. Zhong Xi Yi Jie He Xue Bao, 2004,2(4):297-298
[9] 唐汉钧, 高尚璞, 郑勇 , 等. 中医药治疗乳腺癌术后患者288例临床观察[J]. 上海中医药大学学报, 2002,16(3):23-25
Tang HJ, Gao SP, Zheng Y , et al. Clinical observation of 288 cases treated by Chinese medicine after surgery of mammary cancer[J]. Shanghai Zhong Yi Yao Da Xue Xue Bao, 2002,16(3):23-25
[10] 司徒红林, 林毅, 陈前军 , 等. 中药癌复康对乳腺癌术后化疗患者生存质量的影响[J]. 广州中医药大学学报, 2005,22(1):26-29
Situ HL, Lin Y, Chen QJ , et al. Effect of Aifukang on quality of life of breast cancer patients treated with chemotherapy after operation[J]. Guangzhou Zhong Yi Yao Da Xue Xue Bao, 2005,22(1):26-29
[11] 欧阳华强, 黄雯霞, 刘鲁明 , 等. 消瘕方治疗乳腺癌术后110例的临床观察[J]. 上海中医药杂志, 2006,40(6):50-51
Ouyang HQ, Huang WX, Liu LM , et al. Clinical observation of ''Xiaojia Decoction'' in treating postoperative mammary carcinoma in 110 cases[J]. Shanghai Zhong Yi Yao Za Zhi, 2006,40(6):50-51
[1] Sherman Gu, Arthur Yin Fan. Controversial conclusions from two randomized controlled trials for acupuncture's effects on polycystic ovary syndrome or in vitro fertilization support. Journal of Integrative Medicine, 2020, 18(2): 89-91.
[2] Xue-qing Yu, Shu-guang Yang, Yang Xie, Jian-sheng Li. Traditional Chinese medicine in the treatment of idiopathic pulmonary fibrosis based on syndrome differentiation: Study protocol of exploratory trial. Journal of Integrative Medicine, 2020, 18(2): 163-168.
[3] Chang-quan Ling. Traditional Chinese medicine is a resource for drug discovery against 2019 novel coronavirus (SARS-CoV-2). Journal of Integrative Medicine, 2020, 18(2): 87-88.
[4] Wen Qiang Lee, Jeremy Teoh, Pei Zheng Kenneth Lee, Zhi Xiong Gerard Low, Xueling Sim, Foong Fong Mary Chong, Norbert Ludwig Wagner. Factors influencing communication of traditional Chinese medicine use between patients and doctors: a multisite cross-sectional study. Journal of Integrative Medicine, 2019, 17(6): 396-403.
[5] Charles Dalcanale Tesser, Ari Ojeda Ocampo Moré, Melissa Costa Santos, Emiliana Domingues Cunha da Silva, Fátima Terezinha Pelachini Farias, Lúcio José Botelho. Auriculotherapy in primary health care: A large-scale educational experience in Brazil. Journal of Integrative Medicine, 2019, 17(4): 302-309.
[6] Mikhail Teppone. Medicine has always been “Modern” and “Scientific” from ancient times to the present day. Journal of Integrative Medicine, 2019, 17(4): 229-237.
[7] Rachael Farrington, Ian F.Musgrave, Roger W.Byard. Evidence for the efficacy and safety of herbal weight loss preparations. Journal of Integrative Medicine, 2019, 17(2): 87-92.
[8] Carlos R. Oliveira, Daniel G. Spindola, Daniel M. Garcia, Adolfo Erustes, Alexandre Bechara, Caroline Palmeira-dos-Santos, Soraya S. Smaili, Gustavo J.S. Pereira, André Hinsberger, Ezequiel P. Viriato, Maria Cristina Marcucci, Alexandra C.H.F. Sawaya, Samantha L. Tomaz, Elaine G. Rodrigues, Claudia Bincoletto. Medicinal properties of Angelica archangelica root extract: Cytotoxicity in breast cancer cells and its protective effects against in vivo tumor development. Journal of Integrative Medicine, 2019, 17(2): 132-140.
[9] Fung-Kei Cheng. An overview of the contribution of acupuncture to thyroid disorders. Journal of Integrative Medicine, 2018, 16(6): 375-383.
[10] Chang-quan Ling, Jia Fan, Hong-sheng Lin, Feng Shen, Zhen-ye Xu, Li-zhu Lin, Shu-kui Qin, Wei-ping Zhou, Xiao-feng Zhai, Bai Li, Qing-hui Zhou, on behalf of the Chinese Integrative Therapy of Primary Liver Cancer Working Group. Clinical practice guidelines for the treatment of primary liver cancer with integrative traditional Chinese and Western medicine. Journal of Integrative Medicine, 2018, 16(4): 236-248.
[11] Lizhou Liu, Simone Petrich, Blair McLaren, Lyndell Kelly, G. David Baxter. An integrative Tai Chi program for patients with breast cancer undergoing cancer therapy: Study protocol for a randomized controlled feasibility study. Journal of Integrative Medicine, 2018, 16(2): 99-105.
[12] Gloria Gronowicz, Eric R. Secor Jr., John R. Flynn, Liisa T. Kuhn. Human biofield therapy does not affect tumor size but modulates immune responses in a mouse model for breast cancer. Journal of Integrative Medicine, 2016, 14(5): 389-399.
[13] Qing Ji, Yun-quan Luo, Wen-hai Wang, Xuan Liu, Qi Li, Shi-bing Su. Research advances in traditional Chinese medicine syndromes in cancer patients. Journal of Integrative Medicine, 2016, 14(1): 12-21.
[14] Bing He, Ge Zhang, Ai-ping Lu. Integrative network analysis: Bridging the gap between Western medicine and traditional Chinese medicine. Journal of Integrative Medicine, 2015, 13(3): 133-135.
[15] Zhao-guo Li, Xi-ru Liu. Comparative study on WHO Western Pacific Region and World Federation of Chinese Medicine Societies international standard terminologies on traditional medicine: Diseases of Paediatrics (Part 3). Journal of Integrative Medicine, 2015, 13(3): 201-204.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] Hai-feng Wei, Bai-liu Ya, Ling Zhao, Cui-fei Ye, Li Zhang, Lin Li. Evaluation of tongue manifestation of blood stasis syndrome and its relationship with blood rheological disorder in a rat model of transient brain ischemia. Journal of Chinese Integrative Medicine, 2008, 6(1): 73-76
[2] Ning-qun Wang, Liang-duo Jiang, Zong-xing Li. Research progress in asthma-related quality of life. Journal of Chinese Integrative Medicine, 2008, 6(1): 93-97
[3] Daniel Weber, Janelle M Wheat, Geoffrey M Currie. Inflammation and cancer: Tumor initiation, progression and metastasis,and Chinese botanical medicines. Journal of Chinese Integrative Medicine, 2010, 8(11): 1006-1013
[4] Hong Liu , Guo-liang Zhang, Li Shen , Zhen Zeng, Bao-luo Zhou, Cheng-hai Liu, Guang Nie . Application and evaluation of a pseudotyped virus assay for screening herbs for anti-H5Nl avian influenza virus. Journal of Chinese Integrative Medicine, 2010, 8(11): 1036-1040
[5] Jing-yuan Mao, Chang-xiao Liu, Heng-he Wang, Guang-li Wei , Zhen-peng Zhang, Jie Xing, Wang Xian liang , Ying-fei Bi . Effects of Shenmai Injection on serum concentration and pharmacokinetics of digoxin in dogs with heart failure. Journal of Chinese Integrative Medicine, 2010, 8(11): 1070-1074
[6] Liang-ping Hu , Xiao-lei Bao, Xue Guan. Statistical inference and experimental design of univariate qualitative data of single-group design. Journal of Chinese Integrative Medicine, 2010, 8(11): 1085-1089
[7] Gui Yu, Jie Wang. Thinking on building the network cardiovasology of Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(11): 1206-1210
[8] Dong-tao Li, Jian Wang , Hong-yang Jiang , Feng-lei Shi , Fu-yu Li , Ji-hong Liu , Yong-mei Cheng , Nan Yan , Ai-hua Hu, Mei-zeng Zhang , Jie Li, Ling-bo Wei , Rong-qin Jiang. Quantitative evaluation of the degrees of traditional Chinese medicine qualitative syndromes of osteoporosis. Journal of Chinese Integrative Medicine, 2012, 10(11): 1254-1262
[9] Yang Chen, Jian-hua Huang, You Ning, Zi-yin Shen. Icariin and its pharmaceutical efficacy: Research progress of molecular mechanism. Journal of Chinese Integrative Medicine, 2011, 9(11): 1179-1184
[10] Xiang-yu Kong, Yuan Hao, Tai-xiang Wu, Yan-ming Xie. Adverse drug reactions or adverse events of Chaihu Injection: A systematic review. Journal of Chinese Integrative Medicine, 2010, 8(12): 1124-1132