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Journal of Chinese Integrative Medicine ›› 2012, Vol. 10 ›› Issue (2): 117-127.doi: 10.3736/jcim20120201

• Review •     Next Articles

A recent update in research on the antihepatotoxic potential of medicinal plants

Dhiman Anju1(),Nanda Arun1,Ahmad Sayeed2,3   

  1. 1. Department of Pharmaceutical Sciences, Maharshi Dayanand University, Rohtak 124001, Haryana, India
    2. Bioactive Natural Product Laboratory, Department of Pharmacognosy and Phytochemistry, Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India
    3. Division of Kidney Diseases and Hypertension, Feinstein Institute for Medical Research, New York 11021, USA
  • Received:2011-08-18 Accepted:2011-11-03 Online:2012-02-20 Published:2018-10-09

Hepatic damage is a global metabolic and epidemic disease, affecting essential biochemical activities in almost every age group. Conventional drugs used in the treatment of liver disorders are often inadequate. Also, the spectrum of liver abnormalities caused by allopathic drugs is found to be broad. In view of severely undesirable side effects of synthetic agents, it is necessary to search for alternative drugs for the treatment of liver diseases to replace the currently used drugs, which are of doubtful efficacy and safety. Therefore, there is growing focus to follow systematic research methodology and to evaluate scientific basis for the traditional herbal medicines that are claimed to possess hepatoprotective activities. Use of herbal drugs in the treatment of liver diseases has a long tradition, especially in Eastern medicine and can be traced back as far as 2100 B.C. in ancient China (Xia Dynasty) and India (Vedic period), but evidence for efficacy is sparse. The current study is aimed at providing an overview of clinical and experimental studies carried out on the most effective and commonly used hepatoprotective plants and their beneficial aspects.

Key words: plants, medicinal, plant extracts, hepatoprotective agents, review

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