比较效果研究的内涵和外延及其用于中医临床评价的可行性分析

doi:10.3736/jcim20120403

Abstract

Comparative effectiveness research (CER) is well developed in international medical research. This article analyzes the basic connotations of CER from five aspects, including selection of objective, positioning of target population, comparison of intervention scheme, identification of contrast condition and analysis of therapeutic effects. The inclusiveness and advanced nature of CER were revealed by comparing with modern medical research methods, such as evidence-based medicine, patient-important outcome and randomized controlled trials. Based on the superiority of CER, the feasibility of applying CER in clinical evaluation of traditional Chinese medicine is explored. CER should be combined with the holistic concept, syndrome differentiation and individuality-concerned treatment so as to facilitate its development in research of traditional Chinese medicine in China.

Key words: comparative effectiveness research, traditional Chinese medicine, validation studies as topic, clinical trial

Hong-bo Cao, Hong-cai Shang . Connotations and extensions of comparative effectiveness research and feasibility analysis for clinical evaluation in traditional Chinese medicine. Journal of Chinese Integrative Medicine, 2012, 10(4): 369-374.

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URL: http://www.jcimjournal.com/EN/10.3736/jcim20120403

http://www.jcimjournal.com/EN/Y2012/V10/I4/369

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References 13

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Comparative aspect	Evidence-based medicine	Comparative effectiveness research
Same points
Theoretical origin	Clinical epidemiology	Clinical epidemiology
Base point	The best current evidence	In line with actual clinical evidence
Information sharing	A theoretical basis for comparative effectiveness research	Evidence optimization for evidence-based medicine
Different points
Research objective	To provide the best medical care demand	Integration of medical resources
Research perspective	Emphasis on evidence of internal validity	Emphasis on evidence of actual external validity
Maturity	Relatively mature	Method should be improved

Connotations and extensions of comparative effectiveness research and feasibility analysis for clinical evaluation in traditional Chinese medicine

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